FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010882816> ?p ?o ?g. }

• W2010882816 endingPage "154" @default.
• W2010882816 startingPage "150" @default.
• W2010882816 abstract "1 . 5-Hydroxytryptamine (5-HT) is intimately associated with central sympathetic and somatic control of the lower urinary tract. The sympathetic and somatic innervation of the lower urinary tract is conveyed through efferent axons of the hypogastric and pudendal nerves, respectively. 2 . The present study examined the effects of 2,5-dimethoxy-4-iodophenylisopropylamine (DOI), a 5-HT2 receptor subtype-selective agonist, on evoked potentials recorded from the central ends of the hypogastric and pudendal nerves in response to electrical stimulation of afferent fibres in the pelvic and pudendal nerves, respectively. Various spinalization paradigms were employed to localize the site of action. All cats were pretreated with xylamidine (1 mg kg−1), a peripherally-restricted 5-HT2 receptor antagonist. 3 . In acute spinal cats, DOI (0.01–3 mg kg−1, i.v.) reliably produced dose-dependent increases in the pudendal nerve reflex (to 228±31% of control). These increases were reversed by the 5-HT2 receptor-selective antagonist, LY53857 (0.3-3 mg kg−1, i.v.). On the other hand, in spinally-intact cats, DOI produced no significant changes in the pudendal reflex. However, within minutes of spinalization of DOI-pretreated cats, a marked increase (to 221±16% of control) in the pudendal reflex was observed which could be reversed by LY53857. No significant effects were observed on hypogastric reflexes in either acute spinal or spinally-intact cats following DOI administration. No effects were seen in either spinally-intact or acute spinal animals when LY53857 was administered as the initial drug. 4 . These results indicate that activation of spinal 5-HT2 receptors facilitates pudendal reflexes. In spinally-intact cats, it is hypothesized that DOI activates supraspinal pathways that mediate inhibition of the pudendal reflexes and counteracts the facilitatory effects of spinal 5-HT2 receptor activation." @default.
• W2010882816 created "2016-06-24" @default.
• W2010882816 creator A5003845584 @default.
• W2010882816 creator A5028654330 @default.
• W2010882816 date "1996-05-01" @default.
• W2010882816 modified "2023-10-16" @default.
• W2010882816 title "Spinal 5-HT2 receptor-mediated facilitation of pudendal nerve reflexes in the anaesthetized cat" @default.
• W2010882816 cites W1854111987 @default.
• W2010882816 cites W1979649259 @default.
• W2010882816 cites W1980067374 @default.
• W2010882816 cites W1985799577 @default.
• W2010882816 cites W1992645144 @default.
• W2010882816 cites W1993948323 @default.
• W2010882816 cites W1994301479 @default.
• W2010882816 cites W1994393960 @default.
• W2010882816 cites W2000380515 @default.
• W2010882816 cites W2005438152 @default.
• W2010882816 cites W2020251603 @default.
• W2010882816 cites W2023745986 @default.
• W2010882816 cites W2024742290 @default.
• W2010882816 cites W2028276329 @default.
• W2010882816 cites W2029009093 @default.
• W2010882816 cites W2035665118 @default.
• W2010882816 cites W2044210336 @default.
• W2010882816 cites W2056707790 @default.
• W2010882816 cites W2058653235 @default.
• W2010882816 cites W2073416662 @default.
• W2010882816 cites W2075042560 @default.
• W2010882816 cites W2077041840 @default.
• W2010882816 cites W2077319280 @default.
• W2010882816 cites W2080221012 @default.
• W2010882816 cites W2090618990 @default.
• W2010882816 cites W2094175418 @default.
• W2010882816 cites W2103792310 @default.
• W2010882816 cites W2127428215 @default.
• W2010882816 cites W2153853866 @default.
• W2010882816 cites W2210360753 @default.
• W2010882816 cites W2227342223 @default.
• W2010882816 cites W2229422221 @default.
• W2010882816 cites W2263088773 @default.
• W2010882816 cites W2266270042 @default.
• W2010882816 cites W2281263761 @default.
• W2010882816 cites W2401207431 @default.
• W2010882816 cites W2887369747 @default.
• W2010882816 doi "https://doi.org/10.1111/j.1476-5381.1996.tb15378.x" @default.
• W2010882816 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1909481" @default.
• W2010882816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8733588" @default.
• W2010882816 hasPublicationYear "1996" @default.
• W2010882816 type Work @default.
• W2010882816 sameAs 2010882816 @default.
• W2010882816 citedByCount "86" @default.
• W2010882816 countsByYear W20108828162012 @default.
• W2010882816 countsByYear W20108828162014 @default.
• W2010882816 countsByYear W20108828162017 @default.
• W2010882816 countsByYear W20108828162018 @default.
• W2010882816 countsByYear W20108828162019 @default.
• W2010882816 countsByYear W20108828162020 @default.
• W2010882816 countsByYear W20108828162021 @default.
• W2010882816 countsByYear W20108828162023 @default.
• W2010882816 crossrefType "journal-article" @default.
• W2010882816 hasAuthorship W2010882816A5003845584 @default.
• W2010882816 hasAuthorship W2010882816A5028654330 @default.
• W2010882816 hasBestOaLocation W20108828161 @default.
• W2010882816 hasConcept C118552586 @default.
• W2010882816 hasConcept C126322002 @default.
• W2010882816 hasConcept C134018914 @default.
• W2010882816 hasConcept C170493617 @default.
• W2010882816 hasConcept C24998067 @default.
• W2010882816 hasConcept C2778938600 @default.
• W2010882816 hasConcept C2779013793 @default.
• W2010882816 hasConcept C2779904517 @default.
• W2010882816 hasConcept C2780682423 @default.
• W2010882816 hasConcept C2780775167 @default.
• W2010882816 hasConcept C42219234 @default.
• W2010882816 hasConcept C71924100 @default.
• W2010882816 hasConcept C83974742 @default.
• W2010882816 hasConceptScore W2010882816C118552586 @default.
• W2010882816 hasConceptScore W2010882816C126322002 @default.
• W2010882816 hasConceptScore W2010882816C134018914 @default.
• W2010882816 hasConceptScore W2010882816C170493617 @default.
• W2010882816 hasConceptScore W2010882816C24998067 @default.
• W2010882816 hasConceptScore W2010882816C2778938600 @default.
• W2010882816 hasConceptScore W2010882816C2779013793 @default.
• W2010882816 hasConceptScore W2010882816C2779904517 @default.
• W2010882816 hasConceptScore W2010882816C2780682423 @default.
• W2010882816 hasConceptScore W2010882816C2780775167 @default.
• W2010882816 hasConceptScore W2010882816C42219234 @default.
• W2010882816 hasConceptScore W2010882816C71924100 @default.
• W2010882816 hasConceptScore W2010882816C83974742 @default.
• W2010882816 hasIssue "1" @default.
• W2010882816 hasLocation W20108828161 @default.
• W2010882816 hasLocation W20108828162 @default.
• W2010882816 hasLocation W20108828163 @default.
• W2010882816 hasLocation W20108828164 @default.
• W2010882816 hasOpenAccess W2010882816 @default.
• W2010882816 hasPrimaryLocation W20108828161 @default.
• W2010882816 hasRelatedWork W2022857271 @default.
• W2010882816 hasRelatedWork W2030983661 @default.

• next