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• W2010893722 abstract "Significance We report a novel linear mixed-linkage (1→3)(1→4)-β-glucan produced by the bacterium Sinorhizobium meliloti upon raising cyclic diguanylate (c-di-GMP) intracellular levels. This unique bacterial polysaccharide resembles (1→3)(1→4)-β-glucans found in cereals and certain lichens but has a distinctive primary structure. Genes, proteins, and regulatory pathways for producing this new polymer are described. Our findings open the possibility of using bacteria to produce (1→3)(1→4)-β-glucans, which are receiving increasing interest as bioactive compounds, and provide new elements to disclose molecular mechanisms of c-di-GMP regulation as well as for investigating the evolution, activity, and specificity of glycosyl transferases." @default.
• W2010893722 created "2016-06-24" @default.
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• W2010893722 date "2015-02-03" @default.
• W2010893722 modified "2023-10-17" @default.
• W2010893722 title "Novel mixed-linkage β-glucan activated by c-di-GMP in <i>Sinorhizobium meliloti</i>" @default.
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• W2010893722 doi "https://doi.org/10.1073/pnas.1421748112" @default.
• W2010893722 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4343143" @default.
• W2010893722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25650430" @default.
• W2010893722 hasPublicationYear "2015" @default.
• W2010893722 type Work @default.
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