FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010900583> ?p ?o ?g. }

• W2010900583 endingPage "111" @default.
• W2010900583 startingPage "103" @default.
• W2010900583 abstract "Infection may result in early abnormalities in respiratory movement, and the mechanism may involve central and peripheral factors. Peripheral mechanisms include lung injury and alterations in electrolytes and body temperature, but the central mechanisms remain unclear. In the present study, brainstem slices harvested from rats were stimulated with lipopolysaccharide at different doses. Central respiratory activities as demonstrated by electrophysiological activity of the hypoglossal rootlets were examined and the mechanisms were investigated by inhibiting nitric oxide synthase and ATP-sensitive potassium channels. As a result, 0.5 µg/ml lipopolysaccharide mainly caused inhibitory responses in both the frequency and the output intensity, while 5 µg/ml lipopolysaccharide caused an early frequency increase followed by delayed decreases in both the frequency and the output intensity. At both concentrations the inhibitory responses were fully reversed by inhibition of nitric oxide synthase with Nω-nitro-L-arginine methyl ester hydrochloride (20 µM), and by inhibition of ATP- sensitive potassium channels with glybenclamide (100 µM). These results show that direct lipopolysaccharide challenge altered central respiratory activity in dose- and time- related manners. Nitric oxide synthase and ATP-sensitive potassium channels may be involved in the respiratory changes." @default.
• W2010900583 created "2016-06-24" @default.
• W2010900583 creator A5040809336 @default.
• W2010900583 creator A5043022302 @default.
• W2010900583 creator A5045827227 @default.
• W2010900583 creator A5060893289 @default.
• W2010900583 creator A5069673018 @default.
• W2010900583 creator A5077399736 @default.
• W2010900583 creator A5084856814 @default.
• W2010900583 creator A5088534495 @default.
• W2010900583 date "2012-01-01" @default.
• W2010900583 modified "2023-09-30" @default.
• W2010900583 title "Nitric Oxide and ATP-Sensitive Potassium Channels Mediate Lipopolysaccharide-Induced Depression of Central Respiratory-Like Activity in Brain Slices" @default.
• W2010900583 cites W101885949 @default.
• W2010900583 cites W1581189903 @default.
• W2010900583 cites W1966095368 @default.
• W2010900583 cites W1967657525 @default.
• W2010900583 cites W1975423347 @default.
• W2010900583 cites W1978219247 @default.
• W2010900583 cites W1978768928 @default.
• W2010900583 cites W1986740857 @default.
• W2010900583 cites W2001946056 @default.
• W2010900583 cites W2010801051 @default.
• W2010900583 cites W2012615827 @default.
• W2010900583 cites W2026640844 @default.
• W2010900583 cites W2037688283 @default.
• W2010900583 cites W2040528401 @default.
• W2010900583 cites W2045247260 @default.
• W2010900583 cites W2056955125 @default.
• W2010900583 cites W2065678433 @default.
• W2010900583 cites W2071134312 @default.
• W2010900583 cites W2072878678 @default.
• W2010900583 cites W2072932535 @default.
• W2010900583 cites W2078711199 @default.
• W2010900583 cites W2079983009 @default.
• W2010900583 cites W2083678177 @default.
• W2010900583 cites W2087203965 @default.
• W2010900583 cites W208845662 @default.
• W2010900583 cites W2092111445 @default.
• W2010900583 cites W2132494190 @default.
• W2010900583 cites W2134075323 @default.
• W2010900583 cites W2143937527 @default.
• W2010900583 cites W2150553711 @default.
• W2010900583 cites W2153495810 @default.
• W2010900583 doi "https://doi.org/10.1159/000330841" @default.
• W2010900583 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22327245" @default.
• W2010900583 hasPublicationYear "2012" @default.
• W2010900583 type Work @default.
• W2010900583 sameAs 2010900583 @default.
• W2010900583 citedByCount "7" @default.
• W2010900583 countsByYear W20109005832019 @default.
• W2010900583 countsByYear W20109005832020 @default.
• W2010900583 countsByYear W20109005832022 @default.
• W2010900583 countsByYear W20109005832023 @default.
• W2010900583 crossrefType "journal-article" @default.
• W2010900583 hasAuthorship W2010900583A5040809336 @default.
• W2010900583 hasAuthorship W2010900583A5043022302 @default.
• W2010900583 hasAuthorship W2010900583A5045827227 @default.
• W2010900583 hasAuthorship W2010900583A5060893289 @default.
• W2010900583 hasAuthorship W2010900583A5069673018 @default.
• W2010900583 hasAuthorship W2010900583A5077399736 @default.
• W2010900583 hasAuthorship W2010900583A5084856814 @default.
• W2010900583 hasAuthorship W2010900583A5088534495 @default.
• W2010900583 hasBestOaLocation W20109005831 @default.
• W2010900583 hasConcept C126322002 @default.
• W2010900583 hasConcept C134018914 @default.
• W2010900583 hasConcept C17077164 @default.
• W2010900583 hasConcept C185592680 @default.
• W2010900583 hasConcept C2777622882 @default.
• W2010900583 hasConcept C2778754761 @default.
• W2010900583 hasConcept C42219234 @default.
• W2010900583 hasConcept C519581460 @default.
• W2010900583 hasConcept C534529494 @default.
• W2010900583 hasConcept C551621295 @default.
• W2010900583 hasConcept C71924100 @default.
• W2010900583 hasConcept C83743174 @default.
• W2010900583 hasConcept C86803240 @default.
• W2010900583 hasConcept C98274493 @default.
• W2010900583 hasConceptScore W2010900583C126322002 @default.
• W2010900583 hasConceptScore W2010900583C134018914 @default.
• W2010900583 hasConceptScore W2010900583C17077164 @default.
• W2010900583 hasConceptScore W2010900583C185592680 @default.
• W2010900583 hasConceptScore W2010900583C2777622882 @default.
• W2010900583 hasConceptScore W2010900583C2778754761 @default.
• W2010900583 hasConceptScore W2010900583C42219234 @default.
• W2010900583 hasConceptScore W2010900583C519581460 @default.
• W2010900583 hasConceptScore W2010900583C534529494 @default.
• W2010900583 hasConceptScore W2010900583C551621295 @default.
• W2010900583 hasConceptScore W2010900583C71924100 @default.
• W2010900583 hasConceptScore W2010900583C83743174 @default.
• W2010900583 hasConceptScore W2010900583C86803240 @default.
• W2010900583 hasConceptScore W2010900583C98274493 @default.
• W2010900583 hasIssue "2" @default.
• W2010900583 hasLocation W20109005831 @default.
• W2010900583 hasLocation W20109005832 @default.
• W2010900583 hasOpenAccess W2010900583 @default.
• W2010900583 hasPrimaryLocation W20109005831 @default.
• W2010900583 hasRelatedWork W1585358533 @default.

• next