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- W2010928841 endingPage "4781" @default.
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- W2010928841 abstract "ABSTRACT Actinobacillus pleuropneumoniae , the causative agent of porcine pleuropneumonia, contains a periplasmic Cu- and Zn-cofactored superoxide dismutase ([Cu,Zn]-SOD, or SodC) which has the potential, realized in other pathogens, to promote bacterial survival during infection by dismutating host-defense-derived superoxide. Here we describe the construction of a site-specific, [Cu,Zn]-SOD-deficient A. pleuropneumoniae serotype 1 mutant and show that although the mutant is highly sensitive to the microbicidal action of superoxide in vitro, it remains fully virulent in experimental pulmonary infection in pigs." @default.
- W2010928841 created "2016-06-24" @default.
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- W2010928841 date "2000-08-01" @default.
- W2010928841 modified "2023-10-11" @default.
- W2010928841 title "[Cu,Zn]-Superoxide Dismutase Mutants of the Swine Pathogen <i>Actinobacillus pleuropneumoniae</i> Are Unattenuated in Infections of the Natural Host" @default.
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- W2010928841 doi "https://doi.org/10.1128/iai.68.8.4778-4781.2000" @default.
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