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• W2010976166 abstract "A 70% ethanol extract of the branches of Hippophae rhamnoides exhibited remarkable antitumor activity in an in vivo two-stage carcinogenesis test in mice using 7,12-dimethylbenz[a]anthracene as an initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as a promoter. From the active fraction of the 70% ethanol extract, three phenolic compounds, (+)-catechin (1), (+)-gallocatechin (2), and (-)-epigallocatechin (3) and a tritepenoid, ursolic acid (4) were isolated and identified. These compounds were evaluated for their inhibitory effects on TPA-induced inflammation (1 microg/ear) in mice. Within the tested compounds, 3 and 4 showed marked anti-inflammatory effects, with a 50% inhibitory dose of 1.7 and 0.2 mumol/ear." @default.
• W2010976166 created "2016-06-24" @default.
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• W2010976166 date "2009-04-01" @default.
• W2010976166 modified "2023-10-16" @default.
• W2010976166 title "Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides" @default.
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• W2010976166 doi "https://doi.org/10.1016/j.fitote.2009.01.006" @default.
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