FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010991888> ?p ?o ?g. }

• W2010991888 endingPage "126" @default.
• W2010991888 startingPage "121" @default.
• W2010991888 abstract "Background The best therapeutic strategy for patients with double-vessel coronary artery disease and proximal left anterior descending artery involvement (2VD + pLAD) is not clear. Objectives To compare the survival experience of a cohort of cardiac catheterization patients with 2VD + pLAD based on chosen therapeutic strategy (medical management versus percutaneous coronary intervention [PCI] versus coronary artery bypass graft surgery [CABG]). Methods The authors identified and studied a total of 603 patients with 2VD + pLAD from all patients who underwent diagnostic coronary angiography in Alberta between January 1997 and May 1999. The primary end point was five-year survival from index catheterization for each of the treatment groups and from time of revascularization when the two revascularization strategies were compared. Results Risk-adjusted hazard ratios (HR) comparing cumulative five-year survival rates of patients treated medically, or with PCI or CABG indicated a survival benefit for patients treated with CABG (HR 0.24, 95% CI 0.11 to 0.54; P < 0.001) and PCI (HR 0.43, 95% CI 0.24 to 0.77; P = 0.003) compared with medical management. Meanwhile, a risk-adjusted comparison of revascularization strategies suggested a possible trend toward higher mortality for PCI-treated patients versus CABG-treated patients (HR 1.56, 95% CI 0.65 to 3.72; P=0.125). Conclusions The results of this registry-based observational study suggest a survival benefit from revascularization compared with medical management in patients with 2VD + pLAD. Furthermore, the authors found a trend toward better survival in CABG-treated patients compared with PCI-treated patients. The best therapeutic strategy for patients with double-vessel coronary artery disease and proximal left anterior descending artery involvement (2VD + pLAD) is not clear. To compare the survival experience of a cohort of cardiac catheterization patients with 2VD + pLAD based on chosen therapeutic strategy (medical management versus percutaneous coronary intervention [PCI] versus coronary artery bypass graft surgery [CABG]). The authors identified and studied a total of 603 patients with 2VD + pLAD from all patients who underwent diagnostic coronary angiography in Alberta between January 1997 and May 1999. The primary end point was five-year survival from index catheterization for each of the treatment groups and from time of revascularization when the two revascularization strategies were compared. Risk-adjusted hazard ratios (HR) comparing cumulative five-year survival rates of patients treated medically, or with PCI or CABG indicated a survival benefit for patients treated with CABG (HR 0.24, 95% CI 0.11 to 0.54; P < 0.001) and PCI (HR 0.43, 95% CI 0.24 to 0.77; P = 0.003) compared with medical management. Meanwhile, a risk-adjusted comparison of revascularization strategies suggested a possible trend toward higher mortality for PCI-treated patients versus CABG-treated patients (HR 1.56, 95% CI 0.65 to 3.72; P=0.125). The results of this registry-based observational study suggest a survival benefit from revascularization compared with medical management in patients with 2VD + pLAD. Furthermore, the authors found a trend toward better survival in CABG-treated patients compared with PCI-treated patients." @default.
• W2010991888 created "2016-06-24" @default.
• W2010991888 creator A5002299088 @default.
• W2010991888 creator A5004002184 @default.
• W2010991888 creator A5027674437 @default.
• W2010991888 creator A5079057011 @default.
• W2010991888 creator A5080646995 @default.
• W2010991888 creator A5081088313 @default.
• W2010991888 date "2008-02-01" @default.
• W2010991888 modified "2023-09-26" @default.
• W2010991888 title "Outcomes of revascularization strategies for two-vessel coronary artery disease involving the proximal left anterior descending artery in an era of improved pharmacotherapy and stenting" @default.
• W2010991888 cites W10134696 @default.
• W2010991888 cites W119225588 @default.
• W2010991888 cites W172706899 @default.
• W2010991888 cites W1978989918 @default.
• W2010991888 cites W2008612953 @default.
• W2010991888 cites W2010038681 @default.
• W2010991888 cites W2010514959 @default.
• W2010991888 cites W2012069705 @default.
• W2010991888 cites W2016243977 @default.
• W2010991888 cites W2023234743 @default.
• W2010991888 cites W2052806549 @default.
• W2010991888 cites W2053327848 @default.
• W2010991888 cites W2056503854 @default.
• W2010991888 cites W2083069953 @default.
• W2010991888 cites W2087931190 @default.
• W2010991888 cites W2099273265 @default.
• W2010991888 cites W2110493603 @default.
• W2010991888 cites W2112968496 @default.
• W2010991888 cites W2125462816 @default.
• W2010991888 cites W2128344210 @default.
• W2010991888 cites W2133694538 @default.
• W2010991888 cites W2133875784 @default.
• W2010991888 cites W2145983531 @default.
• W2010991888 cites W2283618120 @default.
• W2010991888 cites W2315638360 @default.
• W2010991888 cites W2340389018 @default.
• W2010991888 cites W2415048463 @default.
• W2010991888 cites W4249549775 @default.
• W2010991888 doi "https://doi.org/10.1016/s0828-282x(08)70567-1" @default.
• W2010991888 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2644566" @default.
• W2010991888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18273485" @default.
• W2010991888 hasPublicationYear "2008" @default.
• W2010991888 type Work @default.
• W2010991888 sameAs 2010991888 @default.
• W2010991888 citedByCount "1" @default.
• W2010991888 crossrefType "journal-article" @default.
• W2010991888 hasAuthorship W2010991888A5002299088 @default.
• W2010991888 hasAuthorship W2010991888A5004002184 @default.
• W2010991888 hasAuthorship W2010991888A5027674437 @default.
• W2010991888 hasAuthorship W2010991888A5079057011 @default.
• W2010991888 hasAuthorship W2010991888A5080646995 @default.
• W2010991888 hasAuthorship W2010991888A5081088313 @default.
• W2010991888 hasBestOaLocation W20109918882 @default.
• W2010991888 hasConcept C126322002 @default.
• W2010991888 hasConcept C141071460 @default.
• W2010991888 hasConcept C164705383 @default.
• W2010991888 hasConcept C168563851 @default.
• W2010991888 hasConcept C203092338 @default.
• W2010991888 hasConcept C207103383 @default.
• W2010991888 hasConcept C2776820930 @default.
• W2010991888 hasConcept C2777385415 @default.
• W2010991888 hasConcept C2778213512 @default.
• W2010991888 hasConcept C2779464278 @default.
• W2010991888 hasConcept C2780400711 @default.
• W2010991888 hasConcept C44249647 @default.
• W2010991888 hasConcept C45393284 @default.
• W2010991888 hasConcept C500558357 @default.
• W2010991888 hasConcept C71924100 @default.
• W2010991888 hasConceptScore W2010991888C126322002 @default.
• W2010991888 hasConceptScore W2010991888C141071460 @default.
• W2010991888 hasConceptScore W2010991888C164705383 @default.
• W2010991888 hasConceptScore W2010991888C168563851 @default.
• W2010991888 hasConceptScore W2010991888C203092338 @default.
• W2010991888 hasConceptScore W2010991888C207103383 @default.
• W2010991888 hasConceptScore W2010991888C2776820930 @default.
• W2010991888 hasConceptScore W2010991888C2777385415 @default.
• W2010991888 hasConceptScore W2010991888C2778213512 @default.
• W2010991888 hasConceptScore W2010991888C2779464278 @default.
• W2010991888 hasConceptScore W2010991888C2780400711 @default.
• W2010991888 hasConceptScore W2010991888C44249647 @default.
• W2010991888 hasConceptScore W2010991888C45393284 @default.
• W2010991888 hasConceptScore W2010991888C500558357 @default.
• W2010991888 hasConceptScore W2010991888C71924100 @default.
• W2010991888 hasIssue "2" @default.
• W2010991888 hasLocation W20109918881 @default.
• W2010991888 hasLocation W20109918882 @default.
• W2010991888 hasLocation W20109918883 @default.
• W2010991888 hasLocation W20109918884 @default.
• W2010991888 hasOpenAccess W2010991888 @default.
• W2010991888 hasPrimaryLocation W20109918881 @default.
• W2010991888 hasRelatedWork W1977637730 @default.
• W2010991888 hasRelatedWork W1996525101 @default.
• W2010991888 hasRelatedWork W2002781300 @default.
• W2010991888 hasRelatedWork W2037123758 @default.
• W2010991888 hasRelatedWork W2110999745 @default.
• W2010991888 hasRelatedWork W2145553842 @default.
• W2010991888 hasRelatedWork W2279559078 @default.

• next