Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010994022> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2010994022 endingPage "59" @default.
- W2010994022 startingPage "56" @default.
- W2010994022 abstract "OBJECTIVE: To study HLA-DR genotypes and to analyze the relationship between HLA-DR genotypes, antineutrophil cytoplasmic antibodies (ANCA) and clinical classification of ulcerative colitis (UC) in Chinese patients. METHODS: Eighty UC patients and 123 healthy subjects were enrolled in the study. Serum ANCA was detected by using indirect immunofluorescence and HLA-DR was genotyped by using the polymerase chain reaction with sequence-specific primers (PCR-SSCP). RESULTS: The positive rate of ANCA in UC patients was 55%, but 0.0% in the controls. The HLA-DR2 and DR15 positive rates in the UC patients were 58.8 and 40%, respectively, which were significantly greater than 30.1 and 17.9% in the controls (P < 0.05). In the UC patients, the DR15-positive rate was significantly higher, but the DR16-positive rate was significantly lower in the ANCA-positive group than in the ANCA-negative group (52.3 vs 25.0%; 9.1 vs 30.6%, P < 0.05). The HLA-DR2 and DR15-positive rates in chronic persistent UC patients were significantly greater than those in the incipient or chronic recrudescent type of UC (84.2 vs 50.0 or 51.4%; 63.2 vs 29.2 or 35.1%, P < 0.05). CONCLUSIONS: In Chinese UC patients, the positive rates of HLA-DR2 and ANCA were significantly higher compared with healthy controls. The increase in the DR2-positive rate was associated with the increase in the DR15-positive rate in ANCA-positive UC patients, and was associated with the increase in the DR16 gene positive rate in ANCA-negative UC patients. In general, HLA-DR genotypes are related to the clinical classification of ulcerative colitis." @default.
- W2010994022 created "2016-06-24" @default.
- W2010994022 creator A5006738333 @default.
- W2010994022 creator A5028433094 @default.
- W2010994022 creator A5046174998 @default.
- W2010994022 creator A5059225203 @default.
- W2010994022 creator A5081031764 @default.
- W2010994022 creator A5087644493 @default.
- W2010994022 date "2002-06-01" @default.
- W2010994022 modified "2023-10-16" @default.
- W2010994022 title "HLA-DR genotypes in Chinese patients with ulcerative colitis" @default.
- W2010994022 cites W1968067289 @default.
- W2010994022 cites W1979404393 @default.
- W2010994022 cites W2012552017 @default.
- W2010994022 cites W2018433894 @default.
- W2010994022 cites W2019300181 @default.
- W2010994022 cites W2022806776 @default.
- W2010994022 cites W2031035500 @default.
- W2010994022 cites W2044439333 @default.
- W2010994022 cites W2059341107 @default.
- W2010994022 cites W2077925418 @default.
- W2010994022 cites W2090383694 @default.
- W2010994022 cites W2110321953 @default.
- W2010994022 cites W2111437358 @default.
- W2010994022 cites W2129812187 @default.
- W2010994022 cites W2142252231 @default.
- W2010994022 cites W2144798387 @default.
- W2010994022 cites W2152567941 @default.
- W2010994022 cites W2153836040 @default.
- W2010994022 doi "https://doi.org/10.1046/j.1443-9573.2002.00075.x" @default.
- W2010994022 hasPublicationYear "2002" @default.
- W2010994022 type Work @default.
- W2010994022 sameAs 2010994022 @default.
- W2010994022 citedByCount "0" @default.
- W2010994022 crossrefType "journal-article" @default.
- W2010994022 hasAuthorship W2010994022A5006738333 @default.
- W2010994022 hasAuthorship W2010994022A5028433094 @default.
- W2010994022 hasAuthorship W2010994022A5046174998 @default.
- W2010994022 hasAuthorship W2010994022A5059225203 @default.
- W2010994022 hasAuthorship W2010994022A5081031764 @default.
- W2010994022 hasAuthorship W2010994022A5087644493 @default.
- W2010994022 hasConcept C104317684 @default.
- W2010994022 hasConcept C126322002 @default.
- W2010994022 hasConcept C135763542 @default.
- W2010994022 hasConcept C24040308 @default.
- W2010994022 hasConcept C2776015282 @default.
- W2010994022 hasConcept C2779134260 @default.
- W2010994022 hasConcept C2780479503 @default.
- W2010994022 hasConcept C55493867 @default.
- W2010994022 hasConcept C71924100 @default.
- W2010994022 hasConcept C86803240 @default.
- W2010994022 hasConcept C90924648 @default.
- W2010994022 hasConceptScore W2010994022C104317684 @default.
- W2010994022 hasConceptScore W2010994022C126322002 @default.
- W2010994022 hasConceptScore W2010994022C135763542 @default.
- W2010994022 hasConceptScore W2010994022C24040308 @default.
- W2010994022 hasConceptScore W2010994022C2776015282 @default.
- W2010994022 hasConceptScore W2010994022C2779134260 @default.
- W2010994022 hasConceptScore W2010994022C2780479503 @default.
- W2010994022 hasConceptScore W2010994022C55493867 @default.
- W2010994022 hasConceptScore W2010994022C71924100 @default.
- W2010994022 hasConceptScore W2010994022C86803240 @default.
- W2010994022 hasConceptScore W2010994022C90924648 @default.
- W2010994022 hasIssue "2" @default.
- W2010994022 hasLocation W20109940221 @default.
- W2010994022 hasOpenAccess W2010994022 @default.
- W2010994022 hasPrimaryLocation W20109940221 @default.
- W2010994022 hasRelatedWork W2003837031 @default.
- W2010994022 hasRelatedWork W2025048290 @default.
- W2010994022 hasRelatedWork W2039392337 @default.
- W2010994022 hasRelatedWork W2146736387 @default.
- W2010994022 hasRelatedWork W2267462133 @default.
- W2010994022 hasRelatedWork W2464962541 @default.
- W2010994022 hasRelatedWork W2475104063 @default.
- W2010994022 hasRelatedWork W2896381073 @default.
- W2010994022 hasRelatedWork W3029739737 @default.
- W2010994022 hasRelatedWork W4254196334 @default.
- W2010994022 hasVolume "3" @default.
- W2010994022 isParatext "false" @default.
- W2010994022 isRetracted "false" @default.
- W2010994022 magId "2010994022" @default.
- W2010994022 workType "article" @default.