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- W2010994024 abstract "Addition of millimolar amounts of a weak base (pyridines) dramatically accelerates the reaction with peroxyl radicals of two biologically relevant uracil derivatives, 5-hydroxyuracil (HU) and 5-hydroxy-6-methyluracil (HMU). This is due to the formation of small amounts of the deprotonated form (pKa = 8.1−8.5 in water), which reacts with peroxyl radicals much faster than the parent undissociated form, via formal H-atom transfer from the OH in the 5 position." @default.
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- W2010994024 date "2010-08-26" @default.
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- W2010994024 title "Base-Promoted Reaction of 5-Hydroxyuracil Derivatives with Peroxyl Radicals" @default.
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- W2010994024 doi "https://doi.org/10.1021/ol1017245" @default.
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