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- W2011024194 abstract "High plasma concentrations of neuropeptide Y (NPY) were found in a patient with bilateral adrenal phaeochromocytomas and medullary thyroid carcinoma associated with MEN IIa (32 pmol/l, normal <3.5 pmol/l). Both adrenal tumours contained and secreted NPY. Manipulation at operation produced a remarkable increase in plasma NPY concentrations (peak =1631 pmol/l) coinciding with increases in plasma levels of catecholamines and arterial pressure. NPY was also shown to be present in thyroid tumour tissue: the concentration of NPY in tumour was 50-fold higher (0.9 nmol/g vs 0.004 nmol/g) than in adjacent normal thyroid tissue. It is possible that NPY from some phaeochromocytomas may contribute to hypertension during surgery." @default.
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- W2011024194 date "1987-01-01" @default.
- W2011024194 modified "2023-10-16" @default.
- W2011024194 title "NEUROPEPTIDE Y IN MULTIPLE ENDOCRINE NEOPLASIA: RELEASE DURING SURGERY FOR PHAEOCHROMOCYTOMA" @default.
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- W2011024194 doi "https://doi.org/10.1111/j.1365-2265.1987.tb03641.x" @default.
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