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- W2011025511 abstract "Annals of the New York Academy of SciencesVolume 723, Issue 1 p. 229-238 Intracellular Ca2+ Transients during Open Heart Surgery: Hypothermic versus Normothermic Cardioplegic Arrest a RICHARD M. ENGELMAN, RICHARD M. ENGELMAN Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorXUEKUN K. LIU, XUEKUN K. LIU Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorJOHN A. ROUSOU, JOHN A. ROUSOU Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorJOSEPH E. FLACK, JOSEPH E. FLACK III Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorDAVID W. DEATON, DAVID W. DEATON Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorDIPAK K. DAS, DIPAK K. DAS Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this author RICHARD M. ENGELMAN, RICHARD M. ENGELMAN Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorXUEKUN K. LIU, XUEKUN K. LIU Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorJOHN A. ROUSOU, JOHN A. ROUSOU Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorJOSEPH E. FLACK, JOSEPH E. FLACK III Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorDAVID W. DEATON, DAVID W. DEATON Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this authorDIPAK K. DAS, DIPAK K. DAS Department of Surgery, Baystate Medical Center, Springfeld, Massachusetts 01199 Cardiovascular Division, Department of Surgery, University of Connecticut Health Center Farmington, Connecticut 06030-1110Search for more papers by this author First published: June 1994 https://doi.org/10.1111/j.1749-6632.1994.tb36729.xCitations: 3 a This work supported by National Institutes of Health Grants HL22559 and HL34360. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Pridjian, A. K., S. Levitsky, I. Krukenkamp, N. A. Silverman & H. Feinberg. 1987. 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Surg. 101: 269– 274. 23 Rousou, J. A., R. M. Engelman, J. E. Flack, D. W. Deaton, X. Liu & D. K. Das. 1991. Comparison of normothermic vs. hypothermic cardioplegia in patients undergoing coronary artery bypass grafting. Surg. Forum 42: 237– 239. 24 Clark, R. E., P. D. Christlieb, A. E. Henry, J. D. Tischer, J. R. Nora, J. R. Williamson & B. E. Sobel. 1979. Nifedipine: a myocardial protective agent. Am. J. Cardiol. 44: 825– 831. 25 Nayler, W. G., R. Ferrari & A. Williams. 1980. Protective effect of pretreatment with verapamil, nifedipine and propranolol on mitochondrial function in the ischemic and reperfused myocardium. Am. J. Cardiol. 46: 242– 248. 26 Watta, J. A., L. J. Maiorano & P. C. Maiorano. 1985. Protection by verapamil of globally ischemic rat hearts: energy preservation, a partial explanation. J. Mol. Cell Cardiol. 17: 797– 804. 27 Bourdillon, P. D. & P. A. Poole-Wilson. 1982. The effects of verapamil, quiescence, and cardioplegia on calcium exchange and mechanical function in ischemic rabbit myocardium. Circ. Res. 50: 360– 368. 28 Morban, E., Y. Koretsune, M. Corretti, V. P. Chacko & H. Kusuoka. 1989. Calcium and its role in myocardial cell injury during ischemia and reperfusion. Circulation 80(Suppl. IV): 17– 22. 29 Mohabir, R., H.-C. Lee, R. W. Kurz & W. T. Clusin. 1991. Effects of ischemia and hypercarbic acidosis on myocyte calcium transients, contraction, and pHi in perfused rabbit hearts. Circ. Res. 69: 1525– 1537. 30 Kihara, Y., W. Grossman & J. P. Morgan. 1989. Direct measurement of changes in intracellular calcium transients during hypoxia, ischemia, and reperfusion of intact mammalian heart. Circ. Res. 65: 1029– 1044. 31 Liu, X., R. M. Engelman, Z. Wei, D. Bagchi, J. A. Rousou, D. Nath & D. K. Das. 1993. Attenuation of myocardial reperrusion injury by reducing intracellular calcium overloading with dihydropyridines. Biochem. Pharmacol. 5: 1333– 1341. 32 Kalfin, R., N. Maulik, R. M. Engelman, G. A. Cordis, K. Milenov, L. Kasakov, & D. K. Das. 1994. Protective role of intracoronary vasoactive intestinal pepride in ischemic and reperfused myocardium. J. Pharmacol. Exp. Therap. 268: 952– 958. 33 Kato, Y., H. Otani, K. Tanaka, Y. Saito, M. Fukunaka & H. Imamura. 1991. Effect of cardioplegic preservation on intracellular calcium transients. Ann. Thoracic Surg. 52: 979– 986. 34 Jacob, R., E. Murphy & M. Lieberman. 1987. Free calcium in isolated chick embryo heart cell measured using quin 2 and fura-2. Am. J. Physiol. 253: C337– C342. 35 Fukumoto, K., H. Takenaka, T. Onitsuka, Y. Koga & M. Hamada. 1991. Effect of hypothermic ischemia and reperfusion on calcium transport by myocardial sarcolemma and sarcoplasmic reticulum. J. Mol. Cell Cardiol. 23: 525– 535. 36 Liu, X., R. M. Engelman, Z. Wei, N. Maulik, J. A. Rousou, J. E. Flack Iii, D. W. Deaton & D. K. Das. 1993. Postischemic deterioration of sarcoplasmic reticulum: warm versus cold blood cardioplegia. Ann. Thoracic Surg. 56: 1154– 1159. 37 Robinson, L. A. & D. L. Harwood. 1991. Lowering the calcium concentration in St. Thomas Hospital cardioplegic solution improves protection during hypothermic ischemia. J. Thoracic Cardiovasc. Surg. 101: 314– 325. 38 Shattock, M. J. & D. M. Bers. 1987. Inotropic response to hypothermia and the temperature-dependence of ryanodine action in isolated rabbit and rat ventricular muscle: implications for excitation-contraction coupling. Circ. Res. 61: 761– 771. 39 Langer, G. A. & A. J. Brady. 1968. The effects of temperature upon contraction and ionic exchange in rabbit ventricular myocardium: relation to control of active state. J. Gen. Physiol. 52: 682– 713. 40 Park, Y. S. & S. K. Hong. 1976. Properties of toad skin Na-K-ATPase with special reference to effect of temperature. Am. J. Physiol. 231: 356– 363. 41 Yamamoto, F., A. S. Manning, M. V. Braimbridge & D. J. Hearse. 1983. Calcium antagonists and myocardial protection: diltiazem during cardioplegic arrest. Thorac. Cardiovasc. Surg. 31: 369– 375. 42 Atkinson, J. B., C. B. Huddleston, R. L. Prager, K. Rybicka, V. A. Starnes & R. Virmani. 1988. The effect of verapamil cardioplegia in myocardial ultrastructure. Am. J. Candiovasc. Pathol. 2: 69– 77. 43 Piper, H. M., P. Koch & P. G. Spieckermann. 1985. Temperature dependence of verapamil action. Basic Res. Cardiol. 10(Suppl. 1): 123– 128. 44 Langer, G. A. 1992. Calcium and the heart: exchange at the tissue, cell, and organelle levels. FASEB J. 6: 893– 902. 45 Nayler, W. G. & J. S. Elz. 1986. Reperfusion injury: laboratory artifact or clinical dilemma Circulation 74: 215– 221. 46 Liu, X. K., R. M. Engelman, J. Iyengar, G. A. Cordis & D. K. Das. 1991. Amiloride enhances postischemic ventricular recovery during cardioplegic arrest. A possible role of Na+-Ca2+ exchange. Ann. N.Y. Acad. Sci. 639: 471– 474. Citing Literature Volume723, Issue1Cellular, Biochemical, and Molecular Aspects of Reperfusion InjuryJune 1994Pages 229-238 ReferencesRelatedInformation" @default.
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