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• W2011032485 abstract "Objective and Background:This study was undertaken to elucidate the relationship between the change of QRS duration with pacing and LV systolic function in paced patients. Biventricular pacing may lead to functional improvement in selected patients with congestive heart failure. This beneficial effect has been associated with a narrowing of the QRS complex during biventricular pacing that may correct discoordinate contraction caused by intraventricular conduction delay. Based on the assumption that QRS width itself may be closely related with LV systolic function, we evaluated the relationship between QRS duration and left ventricular ejection fraction in paced patients. Materials and Methods:The study subjects were pacemaker dependent patients at least a one year after receiving permanent pacemaker. Those patients with a history, or symptoms and signs suggestive of congestive heart failure, significant valvular heart diseases, diabetes mellitus, or underlying bundle branch block prior to pacemaker implantation were excluded. The total numbers of subjects were 50 and their mean age was 63.9 years. Thirty-seven patients received VVI pacemakers and 13 patients dual-chamber pacemakers. Left ventricular ejection fraction was measured by transthoracic echo-cardiography. For QRS width analysis, we used the 12 surface ECGs that were recorded immediately before permanent pacemaker implantation and at the time of measuring the echocardiographic left ventricular ejection fraction during the follow-up period (mean F-U period;55.7±37.5 months). A digitizer (Summasketch III, Summagraphics) was used for measuring the QRS duration. An average of 3 measurements were used to determine QRS duration. The QRS width variables were QRSd;QRS duration of pre-implantation, pQRSd;QRS duration of post-implantation, maxpQRSD;maximal post-implantation QRS duration, DQRSd;difference of QRS duration between preand post-implantation, maxDQRSd;maximum difference of QRS duration between preand post-implantation. Results:The QRSd was 88.0±9.4 msec and did not show any significant correlation with LV EF (r=-0.208, p=0.147). Whereas, pQRSd prolonged to 160.0±2.3 msec showed significant negative correlation with LV EF (r=-0.545, p<0.001). Each of the maxpQRSd (184.0±23.5 msec), DQRSd (72.0±20.5 msec), and maxDQRSd (107.7±23.3 msec) measurements also showed a negative correlation with LV EF respectively (;r=-0.516 & p<0.001, r=-0.500 & p<0.001, r=-0.513 & p<0.001). A similar correlation was also present in subgroup analysis for only the VVI patients. However, the analysis 논문접수일:2000년 7월 10일 심사완료일:2001년 3월 15일 교신저자:이만영, 인천광역시 부평구 부평동 665 가톨릭대학교 의과대학 부속 성모자애병원 내과학교실 전화:(032) 510-5500·전송:(032) 510-5683 E-mail:LEE5679957@netsgo.com" @default.
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• W2011032485 date "2001-01-01" @default.
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• W2011032485 title "The Relationship between QRS duration and LV systolic function in Paced Patients" @default.
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