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- W2011043085 abstract "Many organic compounds containing selenium have shown anticancer effects and some have been used in chemoprevention of cancers and other diseases. Though Se-containing amino acids are generally used for these purposes, the natural nucleosides may also be used as Se-carriers for these important applications. Therefore, we describe here the convenient synthesis of the new 3′-MeSe-thymidine nucleoside and the other uridine and thymidine derivatives modified with MeSe at the 2′ and 5′ positions, and report their anti-tumor activity against prostate cancer cell lines. Our work demonstrates for the first time anticancer activity of the methylseleno nucleosides." @default.
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- W2011043085 date "2009-01-05" @default.
- W2011043085 modified "2023-10-10" @default.
- W2011043085 title "Facile Synthesis and Anti-Tumor Cell Activity of Se-Containing Nucleosides" @default.
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- W2011043085 doi "https://doi.org/10.1080/15257770802581765" @default.
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