FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011052895> ?p ?o ?g. }

• W2011052895 endingPage "258" @default.
• W2011052895 startingPage "253" @default.
• W2011052895 abstract "We assessed changes in gene expression of hypertrophied liver after portal vein ligation (PL) in a test group of rats compared to a control group, which had the same size liver but no PL.The portal veins of the left and median lobes in the test group were ligated in an initial operation. Four days after the PL, the liver volume of the posterior caudate lobe (5%) increased two-fold and comprised 10% of the liver. A 90% hepatectomy was then performed, leaving only the hypertrophied posterior caudate lobe, and leaving the normal anterior and posterior caudate lobes (10%) in the control (sham) group. A comparison of the expression profiles between two groups was performed using cDNA microarrays and the hepatic ATP level was measured.The survival rate for the PL group was significantly higher than for the sham group at 4 days after the hepatectomy (56.3% and 26.7%, P < 0.05). Gene expression of cyclin D1, proliferating cell nuclear antigen, cyclin A and B was upregulated, and the cyclin-dependent kinase inhibitor was downregulated. Increases were observed in: (i) pyruvate dehydrogenase, the tricarboxylic acid cycle cycle regulator, (ii) acyl-CoA dehydrogenase, the oxidation regulator, and (iii) cytochrome oxidases, the oxidative phosphorylation regulator. Hepatic ATP concentration after hepatectomy was better maintained in the PL group than in the sham group (0.48 +/- 0.01 micromol/ml vs. 0.33 +/- 0.01 micromol/ml, P < 0.05).The regenerating liver increased tolerance for extended hepatectomy compared to normal liver. It is believed that this is because the induced rapid regeneration of the remaining liver after hepatectomy increases ATP metabolism." @default.
• W2011052895 created "2016-06-24" @default.
• W2011052895 creator A5003445573 @default.
• W2011052895 creator A5011672031 @default.
• W2011052895 creator A5013015875 @default.
• W2011052895 creator A5015408047 @default.
• W2011052895 creator A5016104984 @default.
• W2011052895 creator A5034453977 @default.
• W2011052895 creator A5068173878 @default.
• W2011052895 creator A5069641755 @default.
• W2011052895 creator A5085779904 @default.
• W2011052895 creator A5087348287 @default.
• W2011052895 date "2004-06-01" @default.
• W2011052895 modified "2023-09-26" @default.
• W2011052895 title "Gene expression profile analysis of regenerating liver after portal vein ligation in rats by a cDNA microarray system" @default.
• W2011052895 cites W1977780753 @default.
• W2011052895 cites W1991656250 @default.
• W2011052895 cites W2007821552 @default.
• W2011052895 cites W2013985215 @default.
• W2011052895 cites W2015451463 @default.
• W2011052895 cites W2023155436 @default.
• W2011052895 cites W2031083076 @default.
• W2011052895 cites W2031846075 @default.
• W2011052895 cites W2040193092 @default.
• W2011052895 cites W2047796164 @default.
• W2011052895 cites W2057749403 @default.
• W2011052895 cites W2085593164 @default.
• W2011052895 cites W2155530972 @default.
• W2011052895 cites W238668910 @default.
• W2011052895 cites W3025972925 @default.
• W2011052895 cites W4233631036 @default.
• W2011052895 doi "https://doi.org/10.1111/j.1478-3231.2004.0912.x" @default.
• W2011052895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15189277" @default.
• W2011052895 hasPublicationYear "2004" @default.
• W2011052895 type Work @default.
• W2011052895 sameAs 2011052895 @default.
• W2011052895 citedByCount "17" @default.
• W2011052895 countsByYear W20110528952013 @default.
• W2011052895 countsByYear W20110528952015 @default.
• W2011052895 countsByYear W20110528952016 @default.
• W2011052895 countsByYear W20110528952020 @default.
• W2011052895 countsByYear W20110528952021 @default.
• W2011052895 crossrefType "journal-article" @default.
• W2011052895 hasAuthorship W2011052895A5003445573 @default.
• W2011052895 hasAuthorship W2011052895A5011672031 @default.
• W2011052895 hasAuthorship W2011052895A5013015875 @default.
• W2011052895 hasAuthorship W2011052895A5015408047 @default.
• W2011052895 hasAuthorship W2011052895A5016104984 @default.
• W2011052895 hasAuthorship W2011052895A5034453977 @default.
• W2011052895 hasAuthorship W2011052895A5068173878 @default.
• W2011052895 hasAuthorship W2011052895A5069641755 @default.
• W2011052895 hasAuthorship W2011052895A5085779904 @default.
• W2011052895 hasAuthorship W2011052895A5087348287 @default.
• W2011052895 hasConcept C104317684 @default.
• W2011052895 hasConcept C121608353 @default.
• W2011052895 hasConcept C126322002 @default.
• W2011052895 hasConcept C134018914 @default.
• W2011052895 hasConcept C141071460 @default.
• W2011052895 hasConcept C150194340 @default.
• W2011052895 hasConcept C153911025 @default.
• W2011052895 hasConcept C159110652 @default.
• W2011052895 hasConcept C171056886 @default.
• W2011052895 hasConcept C199835354 @default.
• W2011052895 hasConcept C202751555 @default.
• W2011052895 hasConcept C204232928 @default.
• W2011052895 hasConcept C2776200302 @default.
• W2011052895 hasConcept C2776795407 @default.
• W2011052895 hasConcept C2776909242 @default.
• W2011052895 hasConcept C29537977 @default.
• W2011052895 hasConcept C34688535 @default.
• W2011052895 hasConcept C55493867 @default.
• W2011052895 hasConcept C71924100 @default.
• W2011052895 hasConcept C86803240 @default.
• W2011052895 hasConcept C95444343 @default.
• W2011052895 hasConceptScore W2011052895C104317684 @default.
• W2011052895 hasConceptScore W2011052895C121608353 @default.
• W2011052895 hasConceptScore W2011052895C126322002 @default.
• W2011052895 hasConceptScore W2011052895C134018914 @default.
• W2011052895 hasConceptScore W2011052895C141071460 @default.
• W2011052895 hasConceptScore W2011052895C150194340 @default.
• W2011052895 hasConceptScore W2011052895C153911025 @default.
• W2011052895 hasConceptScore W2011052895C159110652 @default.
• W2011052895 hasConceptScore W2011052895C171056886 @default.
• W2011052895 hasConceptScore W2011052895C199835354 @default.
• W2011052895 hasConceptScore W2011052895C202751555 @default.
• W2011052895 hasConceptScore W2011052895C204232928 @default.
• W2011052895 hasConceptScore W2011052895C2776200302 @default.
• W2011052895 hasConceptScore W2011052895C2776795407 @default.
• W2011052895 hasConceptScore W2011052895C2776909242 @default.
• W2011052895 hasConceptScore W2011052895C29537977 @default.
• W2011052895 hasConceptScore W2011052895C34688535 @default.
• W2011052895 hasConceptScore W2011052895C55493867 @default.
• W2011052895 hasConceptScore W2011052895C71924100 @default.
• W2011052895 hasConceptScore W2011052895C86803240 @default.
• W2011052895 hasConceptScore W2011052895C95444343 @default.
• W2011052895 hasIssue "3" @default.
• W2011052895 hasLocation W20110528951 @default.
• W2011052895 hasLocation W20110528952 @default.

• next