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- W2011054462 abstract "The role of regulatory T cell populations within the CNS in the regulation of CNS-autoimmunity is controversial. We show that during recovery from relapsing remitting experimental autoimmune encephalomyelitis, regulatory T cells accumulate within the CNS that express high levels of CD62L. These CD62L(high) Treg cells express increased amounts of CTLA-4, ICOS and TGF-β and are more potent than CD62L(low) Treg cells in suppressing proliferation and inducing apoptosis in effector T cells. CD62L(high) Treg cells thus represent a population of Treg cells that display superior immunosuppressive properties and accumulate in the CNS during recovery from CNS-autoimmunity." @default.
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- W2011054462 date "2011-01-01" @default.
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- W2011054462 title "CD62Lhigh Treg cells with superior immunosuppressive properties accumulate within the CNS during remissions of EAE" @default.
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- W2011054462 doi "https://doi.org/10.1016/j.bbi.2010.09.004" @default.
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