FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011101818> ?p ?o ?g. }

• W2011101818 endingPage "138" @default.
• W2011101818 startingPage "131" @default.
• W2011101818 abstract "Background: Odontogenic infections are polymicrobial. This study explores the in vitro killing activity by concentrations similar to those found in crevicular fluid of tinidazole in combination with amoxicillin/clavulanic acid, clindamycin and levofloxacin against four groups of high-density mixed inocula of anaerobes (Prevotella buccae, Fusobacterium nucleatum, and Veillonella spp.) and facultative (Capnocytophaga spp. and Streptococcus spp.) isolates of periodontal pathogens. Methods: Killing curves were assessed under strict anaerobic conditions with antibiotics alone and in combination with tinidazole at concentrations similar to those achieved in crevicular fluid against ∼107 colony forming units (CFU)/ml inoculum (1:1:1:1:1 proportion of the five bacterial isolates) of the four bacterial groups. Group 1 did not include β-lactamase–producing strains; groups 2, 3, and 4 included one, two, and three β-lactamase–producing strains, respectively. Results: In single-drug experiments, at 48 hours, tinidazole alone did not show significant killing of the entire bacterial population, whereas reductions in the initial inocula ≥2.09 log10 CFU/ml with clindamycin, ≥3.26 log10 CFU/ml with amoxicillin/clavulanic acid, and ≥3.83 log10 CFU/ml with levofloxacin were obtained. When combined with tinidazole, reductions were significantly higher for all antibiotics: ≥5.28 log10 CFU/ml with clindamycin, ≥4.78 log10 CFU/ml with amoxicillin/clavulanic acid, and ≥6.17 log10 CFU/ml with levofloxacin. Conclusion: In addition to its high activity against anaerobic periodontal pathogens, tinidazole offered synergism with other antibiotics against the large strict anaerobic subpopulation and the small facultative subpopulation of a high-density mixed inocula of odontogenic pathogens under strict anaerobic conditions, similar to those of odontogenic infections." @default.
• W2011101818 created "2016-06-24" @default.
• W2011101818 creator A5002387045 @default.
• W2011101818 creator A5009272939 @default.
• W2011101818 creator A5016129510 @default.
• W2011101818 creator A5046150579 @default.
• W2011101818 creator A5046495453 @default.
• W2011101818 creator A5055388187 @default.
• W2011101818 creator A5059884537 @default.
• W2011101818 creator A5077448608 @default.
• W2011101818 creator A5081432813 @default.
• W2011101818 creator A5086064346 @default.
• W2011101818 date "2010-01-01" @default.
• W2011101818 modified "2023-10-18" @default.
• W2011101818 title "In Vitro Killing Activity of Crevicular Concentrations of Tinidazole Plus Common Oral Antibiotics Against High-Density Mixed Inocula of Periodontal Pathogens in Strict Anaerobic Conditions" @default.
• W2011101818 cites W1978547466 @default.
• W2011101818 cites W1995293528 @default.
• W2011101818 cites W2005635462 @default.
• W2011101818 cites W2013366826 @default.
• W2011101818 cites W2019803048 @default.
• W2011101818 cites W2020271088 @default.
• W2011101818 cites W2034697164 @default.
• W2011101818 cites W2035773591 @default.
• W2011101818 cites W2115022097 @default.
• W2011101818 cites W2127886138 @default.
• W2011101818 cites W2147095844 @default.
• W2011101818 cites W2153261438 @default.
• W2011101818 doi "https://doi.org/10.1902/jop.2009.090409" @default.
• W2011101818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20059425" @default.
• W2011101818 hasPublicationYear "2010" @default.
• W2011101818 type Work @default.
• W2011101818 sameAs 2011101818 @default.
• W2011101818 citedByCount "2" @default.
• W2011101818 countsByYear W20111018182013 @default.
• W2011101818 countsByYear W20111018182020 @default.
• W2011101818 crossrefType "journal-article" @default.
• W2011101818 hasAuthorship W2011101818A5002387045 @default.
• W2011101818 hasAuthorship W2011101818A5009272939 @default.
• W2011101818 hasAuthorship W2011101818A5016129510 @default.
• W2011101818 hasAuthorship W2011101818A5046150579 @default.
• W2011101818 hasAuthorship W2011101818A5046495453 @default.
• W2011101818 hasAuthorship W2011101818A5055388187 @default.
• W2011101818 hasAuthorship W2011101818A5059884537 @default.
• W2011101818 hasAuthorship W2011101818A5077448608 @default.
• W2011101818 hasAuthorship W2011101818A5081432813 @default.
• W2011101818 hasAuthorship W2011101818A5086064346 @default.
• W2011101818 hasConcept C185592680 @default.
• W2011101818 hasConcept C2777349128 @default.
• W2011101818 hasConcept C2777396551 @default.
• W2011101818 hasConcept C2777458120 @default.
• W2011101818 hasConcept C2778168646 @default.
• W2011101818 hasConcept C2778276568 @default.
• W2011101818 hasConcept C2778753313 @default.
• W2011101818 hasConcept C2779454058 @default.
• W2011101818 hasConcept C2779708577 @default.
• W2011101818 hasConcept C2780183776 @default.
• W2011101818 hasConcept C2780246119 @default.
• W2011101818 hasConcept C2780626017 @default.
• W2011101818 hasConcept C2780960513 @default.
• W2011101818 hasConcept C2781276175 @default.
• W2011101818 hasConcept C2908647359 @default.
• W2011101818 hasConcept C2992397963 @default.
• W2011101818 hasConcept C42407357 @default.
• W2011101818 hasConcept C501593827 @default.
• W2011101818 hasConcept C5140985 @default.
• W2011101818 hasConcept C523546767 @default.
• W2011101818 hasConcept C54355233 @default.
• W2011101818 hasConcept C71924100 @default.
• W2011101818 hasConcept C86803240 @default.
• W2011101818 hasConcept C89423630 @default.
• W2011101818 hasConcept C99454951 @default.
• W2011101818 hasConceptScore W2011101818C185592680 @default.
• W2011101818 hasConceptScore W2011101818C2777349128 @default.
• W2011101818 hasConceptScore W2011101818C2777396551 @default.
• W2011101818 hasConceptScore W2011101818C2777458120 @default.
• W2011101818 hasConceptScore W2011101818C2778168646 @default.
• W2011101818 hasConceptScore W2011101818C2778276568 @default.
• W2011101818 hasConceptScore W2011101818C2778753313 @default.
• W2011101818 hasConceptScore W2011101818C2779454058 @default.
• W2011101818 hasConceptScore W2011101818C2779708577 @default.
• W2011101818 hasConceptScore W2011101818C2780183776 @default.
• W2011101818 hasConceptScore W2011101818C2780246119 @default.
• W2011101818 hasConceptScore W2011101818C2780626017 @default.
• W2011101818 hasConceptScore W2011101818C2780960513 @default.
• W2011101818 hasConceptScore W2011101818C2781276175 @default.
• W2011101818 hasConceptScore W2011101818C2908647359 @default.
• W2011101818 hasConceptScore W2011101818C2992397963 @default.
• W2011101818 hasConceptScore W2011101818C42407357 @default.
• W2011101818 hasConceptScore W2011101818C501593827 @default.
• W2011101818 hasConceptScore W2011101818C5140985 @default.
• W2011101818 hasConceptScore W2011101818C523546767 @default.
• W2011101818 hasConceptScore W2011101818C54355233 @default.
• W2011101818 hasConceptScore W2011101818C71924100 @default.
• W2011101818 hasConceptScore W2011101818C86803240 @default.
• W2011101818 hasConceptScore W2011101818C89423630 @default.
• W2011101818 hasConceptScore W2011101818C99454951 @default.
• W2011101818 hasIssue "1" @default.
• W2011101818 hasLocation W20111018181 @default.

• next