Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011105083> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2011105083 endingPage "295" @default.
- W2011105083 startingPage "291" @default.
- W2011105083 abstract "Boc-Tyr(SO3)-Nle-Gly-Trp-Nle-Asp-2-phenylether ester (CCK-JMV-180) has been reported to be a CCK-based heptipeptide with novel in vitro properties. Based on studies conducted in rat and mouse pancreatic acini, it has been proposed that the compound acts as an agonist the high-affinity site and an antagonist at the low-affinity site in the rat, but as an agonist at both sites in the mouse. In the present study, we examined the effects of CCK-JMV-180 on locomotor activity in the rat and on intake of a liquid diet in the rat and mouse. Although CCK-JMV-180 slightly reduced activity on its own in the rat, it completely reversed the suppression produced by coadministration of CCK-8. In rat feeding studies, CCK-JMV-180 failed to suppress intakes of a liquid diet, but was able to antagonize the anorectic effects of CCK-8. In contrast, in the mouse CCK-JMV-180 potently suppressed intakes on its own, and this effect was blocked by pretreatment with the selective CCK-A receptor antagonist, A-70104. The results of these studies suggest that similar receptor mechanisms are involved in CCK's ability to inhibit food intake in vivo and its effects on pancreatic function in vitro." @default.
- W2011105083 created "2016-06-24" @default.
- W2011105083 creator A5020642706 @default.
- W2011105083 creator A5086075511 @default.
- W2011105083 date "1992-06-01" @default.
- W2011105083 modified "2023-10-11" @default.
- W2011105083 title "Differential effects of CCK-JMV-180 on food intake in rats and mice" @default.
- W2011105083 cites W1544601757 @default.
- W2011105083 cites W1600119213 @default.
- W2011105083 cites W1998664134 @default.
- W2011105083 cites W2028374142 @default.
- W2011105083 cites W2036130808 @default.
- W2011105083 cites W2052006481 @default.
- W2011105083 cites W2068208278 @default.
- W2011105083 cites W2093053031 @default.
- W2011105083 doi "https://doi.org/10.1016/0091-3057(92)90529-o" @default.
- W2011105083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1631182" @default.
- W2011105083 hasPublicationYear "1992" @default.
- W2011105083 type Work @default.
- W2011105083 sameAs 2011105083 @default.
- W2011105083 citedByCount "22" @default.
- W2011105083 countsByYear W20111050832014 @default.
- W2011105083 countsByYear W20111050832018 @default.
- W2011105083 crossrefType "journal-article" @default.
- W2011105083 hasAuthorship W2011105083A5020642706 @default.
- W2011105083 hasAuthorship W2011105083A5086075511 @default.
- W2011105083 hasConcept C126322002 @default.
- W2011105083 hasConcept C134018914 @default.
- W2011105083 hasConcept C150903083 @default.
- W2011105083 hasConcept C170493617 @default.
- W2011105083 hasConcept C185592680 @default.
- W2011105083 hasConcept C202751555 @default.
- W2011105083 hasConcept C207001950 @default.
- W2011105083 hasConcept C2776885963 @default.
- W2011105083 hasConcept C2777369949 @default.
- W2011105083 hasConcept C2777593968 @default.
- W2011105083 hasConcept C2778938600 @default.
- W2011105083 hasConcept C3018685816 @default.
- W2011105083 hasConcept C55493867 @default.
- W2011105083 hasConcept C71924100 @default.
- W2011105083 hasConcept C86803240 @default.
- W2011105083 hasConceptScore W2011105083C126322002 @default.
- W2011105083 hasConceptScore W2011105083C134018914 @default.
- W2011105083 hasConceptScore W2011105083C150903083 @default.
- W2011105083 hasConceptScore W2011105083C170493617 @default.
- W2011105083 hasConceptScore W2011105083C185592680 @default.
- W2011105083 hasConceptScore W2011105083C202751555 @default.
- W2011105083 hasConceptScore W2011105083C207001950 @default.
- W2011105083 hasConceptScore W2011105083C2776885963 @default.
- W2011105083 hasConceptScore W2011105083C2777369949 @default.
- W2011105083 hasConceptScore W2011105083C2777593968 @default.
- W2011105083 hasConceptScore W2011105083C2778938600 @default.
- W2011105083 hasConceptScore W2011105083C3018685816 @default.
- W2011105083 hasConceptScore W2011105083C55493867 @default.
- W2011105083 hasConceptScore W2011105083C71924100 @default.
- W2011105083 hasConceptScore W2011105083C86803240 @default.
- W2011105083 hasIssue "2" @default.
- W2011105083 hasLocation W20111050831 @default.
- W2011105083 hasLocation W20111050832 @default.
- W2011105083 hasOpenAccess W2011105083 @default.
- W2011105083 hasPrimaryLocation W20111050831 @default.
- W2011105083 hasRelatedWork W1973688049 @default.
- W2011105083 hasRelatedWork W1987539780 @default.
- W2011105083 hasRelatedWork W2021975014 @default.
- W2011105083 hasRelatedWork W2030455127 @default.
- W2011105083 hasRelatedWork W2033181528 @default.
- W2011105083 hasRelatedWork W2079941274 @default.
- W2011105083 hasRelatedWork W2094787469 @default.
- W2011105083 hasRelatedWork W2114161702 @default.
- W2011105083 hasRelatedWork W2125471807 @default.
- W2011105083 hasRelatedWork W2127462656 @default.
- W2011105083 hasVolume "42" @default.
- W2011105083 isParatext "false" @default.
- W2011105083 isRetracted "false" @default.
- W2011105083 magId "2011105083" @default.
- W2011105083 workType "article" @default.