Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011107439> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2011107439 endingPage "503" @default.
- W2011107439 startingPage "497" @default.
- W2011107439 abstract "Oscillatory afterpotentials in cardiac tissues are believed to result from an activation of calcium-operated cation channels of mixed selectivity (sodium, potassium), or perturbation of an electrogenic sodium-calcium exchange carrier, by an oscillatory release of calcium from sarcoplasmic reticulum. In the present experiments, the presence and properties of ouabain-induced oscillatory afterpotentials were examined in young (3-day-old) embryonic chick hearts, both fresh and organ cultured for 6-14 days. The hearts did not differentiate in organ culture, and the cells retained slowly rising spontaneous action potentials. To induce the oscillatory afterpotentials, automaticity was suppressed by elevating extracellular K+ ion concentration from 4 mM to 6 mM, and the preparations were electrically stimulated at a rate of 0.5 Hz. Stable oscillatory afterpotentials were induced with 1.3-7.5 microM ouabain. The oscillatory afterpotential amplitude was increased when the stimulation rate was increased to 3 and 4 Hz. The oscillatory afterpotentials were potentiated when extracellular Ca++ ion concentration was increased to 3.6 mM or by the addition of barium (0.1 mM). Low extracellular Na+ ion concentration (40-121 mM), strontium (4 mM), magnesium (2-4 mM), and manganese (1-4 mM) significantly depressed the oscillatory afterpotentials. These properties of the oscillatory afterpotentials are similar to those described for adult mammalian ventricular muscles and Purkinje fibers. Our results suggest that young embryonic chick hearts (which lack fast sodium channels and, instead, have slow sodium channels) possess the calcium-operated mixed cation channels at a very early developmental stage if the oscillatory afterpotentials result from the activation of the mixed cation channels by intracellular calcium." @default.
- W2011107439 created "2016-06-24" @default.
- W2011107439 creator A5045290366 @default.
- W2011107439 creator A5075739260 @default.
- W2011107439 date "1984-10-01" @default.
- W2011107439 modified "2023-09-28" @default.
- W2011107439 title "Properties of oscillatory afterpotentials in young embryonic chick hearts." @default.
- W2011107439 cites W1967677067 @default.
- W2011107439 cites W1976088296 @default.
- W2011107439 cites W1978819017 @default.
- W2011107439 cites W1982913074 @default.
- W2011107439 cites W1987623233 @default.
- W2011107439 cites W1987894568 @default.
- W2011107439 cites W1997540939 @default.
- W2011107439 cites W2004454757 @default.
- W2011107439 cites W2019917327 @default.
- W2011107439 cites W2038820619 @default.
- W2011107439 cites W2044579960 @default.
- W2011107439 cites W2050831484 @default.
- W2011107439 cites W2066542196 @default.
- W2011107439 cites W2070181871 @default.
- W2011107439 cites W2080692788 @default.
- W2011107439 cites W2089123851 @default.
- W2011107439 cites W2097867934 @default.
- W2011107439 cites W2098234794 @default.
- W2011107439 cites W2117594247 @default.
- W2011107439 cites W2121804197 @default.
- W2011107439 cites W2127867283 @default.
- W2011107439 cites W2151550074 @default.
- W2011107439 cites W2154679454 @default.
- W2011107439 cites W2155587357 @default.
- W2011107439 cites W2166932524 @default.
- W2011107439 cites W2171250612 @default.
- W2011107439 cites W2181632133 @default.
- W2011107439 cites W2188721957 @default.
- W2011107439 cites W2885043399 @default.
- W2011107439 cites W2896272918 @default.
- W2011107439 cites W2054796074 @default.
- W2011107439 doi "https://doi.org/10.1161/01.res.55.4.497" @default.
- W2011107439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6090036" @default.
- W2011107439 hasPublicationYear "1984" @default.
- W2011107439 type Work @default.
- W2011107439 sameAs 2011107439 @default.
- W2011107439 citedByCount "10" @default.
- W2011107439 crossrefType "journal-article" @default.
- W2011107439 hasAuthorship W2011107439A5045290366 @default.
- W2011107439 hasAuthorship W2011107439A5075739260 @default.
- W2011107439 hasBestOaLocation W20111074391 @default.
- W2011107439 hasConcept C105702510 @default.
- W2011107439 hasConcept C12554922 @default.
- W2011107439 hasConcept C126322002 @default.
- W2011107439 hasConcept C158617107 @default.
- W2011107439 hasConcept C178790620 @default.
- W2011107439 hasConcept C185592680 @default.
- W2011107439 hasConcept C2779133857 @default.
- W2011107439 hasConcept C28406088 @default.
- W2011107439 hasConcept C517785266 @default.
- W2011107439 hasConcept C519063684 @default.
- W2011107439 hasConcept C537181965 @default.
- W2011107439 hasConcept C55493867 @default.
- W2011107439 hasConcept C71924100 @default.
- W2011107439 hasConcept C86803240 @default.
- W2011107439 hasConceptScore W2011107439C105702510 @default.
- W2011107439 hasConceptScore W2011107439C12554922 @default.
- W2011107439 hasConceptScore W2011107439C126322002 @default.
- W2011107439 hasConceptScore W2011107439C158617107 @default.
- W2011107439 hasConceptScore W2011107439C178790620 @default.
- W2011107439 hasConceptScore W2011107439C185592680 @default.
- W2011107439 hasConceptScore W2011107439C2779133857 @default.
- W2011107439 hasConceptScore W2011107439C28406088 @default.
- W2011107439 hasConceptScore W2011107439C517785266 @default.
- W2011107439 hasConceptScore W2011107439C519063684 @default.
- W2011107439 hasConceptScore W2011107439C537181965 @default.
- W2011107439 hasConceptScore W2011107439C55493867 @default.
- W2011107439 hasConceptScore W2011107439C71924100 @default.
- W2011107439 hasConceptScore W2011107439C86803240 @default.
- W2011107439 hasIssue "4" @default.
- W2011107439 hasLocation W20111074391 @default.
- W2011107439 hasLocation W20111074392 @default.
- W2011107439 hasOpenAccess W2011107439 @default.
- W2011107439 hasPrimaryLocation W20111074391 @default.
- W2011107439 hasRelatedWork W125401218 @default.
- W2011107439 hasRelatedWork W1469370412 @default.
- W2011107439 hasRelatedWork W1965391744 @default.
- W2011107439 hasRelatedWork W2024094716 @default.
- W2011107439 hasRelatedWork W2056008951 @default.
- W2011107439 hasRelatedWork W2111321714 @default.
- W2011107439 hasRelatedWork W2155281951 @default.
- W2011107439 hasRelatedWork W2312051945 @default.
- W2011107439 hasRelatedWork W2338294127 @default.
- W2011107439 hasRelatedWork W2012374663 @default.
- W2011107439 hasVolume "55" @default.
- W2011107439 isParatext "false" @default.
- W2011107439 isRetracted "false" @default.
- W2011107439 magId "2011107439" @default.
- W2011107439 workType "article" @default.