Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011111212> ?p ?o ?g. }
- W2011111212 endingPage "1468" @default.
- W2011111212 startingPage "1459" @default.
- W2011111212 abstract "OBJECTIVE: To review the management of the older person after myocardial infarction (MI). DATA SOURCES: A computer-assisted search of the English language literature (MEDLINE database) followed by a manual search of the bibliographies of pertinent articles. STUDY SELECTION: Studies on the management of persons after MI were screened for review. Studies in persons older than 60 years and recent studies were emphasized. DATA EXTRACTION: Pertinent data were extracted from the reviewed articles. Emphasis was on studies involving older persons. Relevant articles were reviewed in depth. DATA SYNTHESIS: Available data about therapy of persons after MI, including control of risk factors, use of aspirin and beta-blockers, and indications for use of angiotensin-converting enzyme inhibitors, long-term anticoagulant therapy, nitrates, calcium channel blockers, hormone replacement therapy, antiarrhythmic drugs, the automatic implantable cardioverter-defibrillator, and revascularization, with emphasis on studies involving older persons, were summarized. CONCLUSIONS: Risk factors for coronary artery disease should be controlled after MI in older persons. A serum low-density lipoprotein (LDL) cholesterol > 125 mg/dL after MI should be treated with lipid-lowering drug therapy to decrease the serum LDL cholesterol to < 100 mg/dL. Aspirin in a dose of 160 mg to 325 mg daily should be given indefinitely. Indications for long-term anticoagulant therapy with warfarin after MI to maintain an international normalized ratio between 2.0 and 3.0 include secondary prevention of MI in persons unable to tolerate daily aspirin, persistent atrial fibrillation, and left ventricular thrombus. Beta-blockers should be given indefinitely. Angiotensin-converting enzyme inhibitors should be given to persons who have congestive heart failure, an anterior MI, or a left ventricular ejection fraction ≤ 40%. Calcium channel blockers should not be used unless there is persistent angina pectoris despite beta-blockers and nitrates. Antiarrhythmic drugs other than beta-blockers should not be used. An automatic implantable cardioverter-defibrillator should be used in persons who have a history of ventricular fibrillation or serious sustained ventricular tachycardia or who are at very high risk for developing sudden cardiac death. Until data from the Heart Estrogen/Progestin Replacement Study are available, use of an estrogen/progestin regimen is recommended in the treatment of postmenopausal women after MI unless they are at increased risk for developing breast cancer. The two indications for revascularization in older persons after MI are prolongation of life and relief of unacceptable symptoms despite optimal medical management." @default.
- W2011111212 created "2016-06-24" @default.
- W2011111212 creator A5091070572 @default.
- W2011111212 date "1998-11-01" @default.
- W2011111212 modified "2023-10-15" @default.
- W2011111212 title "Management of Older Persons After Myocardial Infarction" @default.
- W2011111212 cites W1971501808 @default.
- W2011111212 cites W1972981120 @default.
- W2011111212 cites W1973139683 @default.
- W2011111212 cites W1974022871 @default.
- W2011111212 cites W1981759659 @default.
- W2011111212 cites W1981895083 @default.
- W2011111212 cites W1983107066 @default.
- W2011111212 cites W1984595407 @default.
- W2011111212 cites W1993822698 @default.
- W2011111212 cites W1994217394 @default.
- W2011111212 cites W1994640924 @default.
- W2011111212 cites W1994729171 @default.
- W2011111212 cites W1995547316 @default.
- W2011111212 cites W1999010325 @default.
- W2011111212 cites W2008833860 @default.
- W2011111212 cites W2011831250 @default.
- W2011111212 cites W2013328893 @default.
- W2011111212 cites W2013562944 @default.
- W2011111212 cites W2016216732 @default.
- W2011111212 cites W2036123834 @default.
- W2011111212 cites W2041553203 @default.
- W2011111212 cites W2044066871 @default.
- W2011111212 cites W2046383587 @default.
- W2011111212 cites W2046981726 @default.
- W2011111212 cites W2048625978 @default.
- W2011111212 cites W2048939683 @default.
- W2011111212 cites W2050730890 @default.
- W2011111212 cites W2052242574 @default.
- W2011111212 cites W2054566345 @default.
- W2011111212 cites W2059356295 @default.
- W2011111212 cites W2060768152 @default.
- W2011111212 cites W2061245702 @default.
- W2011111212 cites W2066298250 @default.
- W2011111212 cites W2068895834 @default.
- W2011111212 cites W2072361968 @default.
- W2011111212 cites W2075022145 @default.
- W2011111212 cites W2075061564 @default.
- W2011111212 cites W2075130101 @default.
- W2011111212 cites W2080297195 @default.
- W2011111212 cites W2083625183 @default.
- W2011111212 cites W2086003060 @default.
- W2011111212 cites W2088021184 @default.
- W2011111212 cites W2088171954 @default.
- W2011111212 cites W2088545325 @default.
- W2011111212 cites W2088661095 @default.
- W2011111212 cites W2088864406 @default.
- W2011111212 cites W2090674352 @default.
- W2011111212 cites W2092805838 @default.
- W2011111212 cites W2094152303 @default.
- W2011111212 cites W2109205562 @default.
- W2011111212 cites W2109740912 @default.
- W2011111212 cites W2111243875 @default.
- W2011111212 cites W2112829244 @default.
- W2011111212 cites W2113083707 @default.
- W2011111212 cites W2114634962 @default.
- W2011111212 cites W2119369921 @default.
- W2011111212 cites W2120937760 @default.
- W2011111212 cites W2120955256 @default.
- W2011111212 cites W2128036159 @default.
- W2011111212 cites W2135566843 @default.
- W2011111212 cites W2141789110 @default.
- W2011111212 cites W2143518969 @default.
- W2011111212 cites W2144238512 @default.
- W2011111212 cites W2144631770 @default.
- W2011111212 cites W2145144040 @default.
- W2011111212 cites W2167759667 @default.
- W2011111212 cites W2169982013 @default.
- W2011111212 cites W2172282913 @default.
- W2011111212 cites W2269745365 @default.
- W2011111212 cites W2312388685 @default.
- W2011111212 cites W2314394525 @default.
- W2011111212 cites W2320382602 @default.
- W2011111212 cites W2322095705 @default.
- W2011111212 cites W2323549932 @default.
- W2011111212 cites W2323738871 @default.
- W2011111212 cites W2326354230 @default.
- W2011111212 cites W2326508838 @default.
- W2011111212 cites W2332349182 @default.
- W2011111212 cites W2333702587 @default.
- W2011111212 cites W2336475481 @default.
- W2011111212 cites W2616111235 @default.
- W2011111212 cites W2727581825 @default.
- W2011111212 cites W3022929210 @default.
- W2011111212 cites W4230087422 @default.
- W2011111212 cites W4231217206 @default.
- W2011111212 cites W4231250029 @default.
- W2011111212 cites W4239471829 @default.
- W2011111212 cites W4240955162 @default.
- W2011111212 cites W4242869084 @default.
- W2011111212 cites W4244341064 @default.
- W2011111212 cites W4249101651 @default.
- W2011111212 cites W4252376983 @default.