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• W2011120838 abstract "Objectives: To define the patterns and causes of hearing decline associated to Turner’s syndrome (TS).Methods: An observational study with three cohorts was designed: 31 TS patients, 15 women with other congenital hypogonadims (OCH) and 41 healthy age-matched women taking contraception. Microotoscopy, standard pure-tone audiometry brain auditory evoked potentials (BAEP) were performed to study hearing function.Results: Up to 87% of TS subjects suffered from some degree of hearing loss (HL) in the audiograms, compared with 20% OCH and 27% controls. Sensorineural hearing loss (SNHL) was the most frequent type of hypoacusia found in TS group. BAEP study demonstrated that 61% of TS women showed HL compared to 20% in OCH patients. No significant differences in latencies, amplitudes, and interpeaks of waves I, III and V were found between TS and OCH, nor when compared to reference population. Worse results were observed among the oldest TS patients, those with pure monosomy or isochromosome, and those with a history of recurrent otitis.Conclusions: More than a half of TS females presented HL. SNHL is the most frequent pattern among middle-aged women with TS. Old age, karyotype and recurrent otitis are predisposition factors to produce HL, while oestrogens play a minor role." @default.
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• W2011120838 date "2013-11-20" @default.
• W2011120838 modified "2023-10-16" @default.
• W2011120838 title "Hearing loss in adult women with Turner’s syndrome and other congenital hypogonadisms" @default.
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• W2011120838 doi "https://doi.org/10.3109/09513590.2013.856002" @default.
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