FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011128550> ?p ?o ?g. }

• W2011128550 endingPage "23" @default.
• W2011128550 startingPage "16" @default.
• W2011128550 abstract "A soil isolate designated 90-F-45-14, belonging to Bacillus thuringiensis serovar dakota (H15), was examined for characterization of in vitro cytotoxicity, associated with parasporal inclusion proteins, against human cells. When activated with proteolytic processing, inclusion proteins of the isolate 90-F-45-14 exhibited a moderate cytotoxicity against the human uterus cervix cancer cells (HeLa) with an EC(50) value of 60.8 microg ml(-1), while showing extremely high activities on the human leukaemic T cells (MOLT-4) and the normal T cells with EC(50) values of 0.27 and 0.20 microg ml(-1), respectively. Anti-leukaemic cell activity of the 90-F-45-14 proteins was eight to nine times greater than that of the B. thuringiensis serovar israelensis proteins containing the Cyt1 protein, a broad-spectrum cytolysin. The cytopathy by the 90-F-45-14 proteins was characterized by marked cell-ballooning, while the israelensis proteins induced early breakdown of the cells due to cytolysis. Inclusions of the isolate consisted of five major polypeptides of 170, 103, 73, 40 and 32 kDa. A 100% homology was observed in the sequence of 15 N-terminal amino acids between the proteins of 170 and 103 kDa. There was no N-terminal sequence homology between 90-F-45-14 proteins and the existing Cry/Cyt proteins of B. thuringiensis. Proteolytic processing by proteinase K yielded several proteins with molecular masses ranging from 40 to 28 kDa." @default.
• W2011128550 created "2016-06-24" @default.
• W2011128550 creator A5001438600 @default.
• W2011128550 creator A5005685892 @default.
• W2011128550 creator A5020000898 @default.
• W2011128550 creator A5021722377 @default.
• W2011128550 creator A5023384774 @default.
• W2011128550 creator A5057882129 @default.
• W2011128550 creator A5067822646 @default.
• W2011128550 creator A5078636853 @default.
• W2011128550 date "2000-07-01" @default.
• W2011128550 modified "2023-09-24" @default.
• W2011128550 title "In vitro cytotoxicity of non-Cyt inclusion proteins of a Bacillus thuringiensis isolate against human cells, including cancer cells" @default.
• W2011128550 cites W1515878708 @default.
• W2011128550 cites W1526560480 @default.
• W2011128550 cites W1775749144 @default.
• W2011128550 cites W1934642468 @default.
• W2011128550 cites W1981014117 @default.
• W2011128550 cites W1981211647 @default.
• W2011128550 cites W1987007767 @default.
• W2011128550 cites W2000130094 @default.
• W2011128550 cites W2013261570 @default.
• W2011128550 cites W2029552699 @default.
• W2011128550 cites W2050267428 @default.
• W2011128550 cites W2059625761 @default.
• W2011128550 cites W2068040746 @default.
• W2011128550 cites W2068076835 @default.
• W2011128550 cites W2076386119 @default.
• W2011128550 cites W2089867775 @default.
• W2011128550 cites W2089919869 @default.
• W2011128550 cites W2100837269 @default.
• W2011128550 cites W2107847732 @default.
• W2011128550 cites W2148358473 @default.
• W2011128550 cites W2164699464 @default.
• W2011128550 cites W2171314806 @default.
• W2011128550 cites W327643136 @default.
• W2011128550 cites W4232503798 @default.
• W2011128550 doi "https://doi.org/10.1046/j.1365-2672.2000.01087.x" @default.
• W2011128550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10945774" @default.
• W2011128550 hasPublicationYear "2000" @default.
• W2011128550 type Work @default.
• W2011128550 sameAs 2011128550 @default.
• W2011128550 citedByCount "27" @default.
• W2011128550 countsByYear W20111285502013 @default.
• W2011128550 countsByYear W20111285502014 @default.
• W2011128550 countsByYear W20111285502017 @default.
• W2011128550 countsByYear W20111285502019 @default.
• W2011128550 countsByYear W20111285502020 @default.
• W2011128550 crossrefType "journal-article" @default.
• W2011128550 hasAuthorship W2011128550A5001438600 @default.
• W2011128550 hasAuthorship W2011128550A5005685892 @default.
• W2011128550 hasAuthorship W2011128550A5020000898 @default.
• W2011128550 hasAuthorship W2011128550A5021722377 @default.
• W2011128550 hasAuthorship W2011128550A5023384774 @default.
• W2011128550 hasAuthorship W2011128550A5057882129 @default.
• W2011128550 hasAuthorship W2011128550A5067822646 @default.
• W2011128550 hasAuthorship W2011128550A5078636853 @default.
• W2011128550 hasConcept C104317684 @default.
• W2011128550 hasConcept C109316439 @default.
• W2011128550 hasConcept C153911025 @default.
• W2011128550 hasConcept C202751555 @default.
• W2011128550 hasConcept C203750385 @default.
• W2011128550 hasConcept C2777366897 @default.
• W2011128550 hasConcept C2779035793 @default.
• W2011128550 hasConcept C523546767 @default.
• W2011128550 hasConcept C54355233 @default.
• W2011128550 hasConcept C547475151 @default.
• W2011128550 hasConcept C55493867 @default.
• W2011128550 hasConcept C60987743 @default.
• W2011128550 hasConcept C73588182 @default.
• W2011128550 hasConcept C80595800 @default.
• W2011128550 hasConcept C86803240 @default.
• W2011128550 hasConcept C89423630 @default.
• W2011128550 hasConceptScore W2011128550C104317684 @default.
• W2011128550 hasConceptScore W2011128550C109316439 @default.
• W2011128550 hasConceptScore W2011128550C153911025 @default.
• W2011128550 hasConceptScore W2011128550C202751555 @default.
• W2011128550 hasConceptScore W2011128550C203750385 @default.
• W2011128550 hasConceptScore W2011128550C2777366897 @default.
• W2011128550 hasConceptScore W2011128550C2779035793 @default.
• W2011128550 hasConceptScore W2011128550C523546767 @default.
• W2011128550 hasConceptScore W2011128550C54355233 @default.
• W2011128550 hasConceptScore W2011128550C547475151 @default.
• W2011128550 hasConceptScore W2011128550C55493867 @default.
• W2011128550 hasConceptScore W2011128550C60987743 @default.
• W2011128550 hasConceptScore W2011128550C73588182 @default.
• W2011128550 hasConceptScore W2011128550C80595800 @default.
• W2011128550 hasConceptScore W2011128550C86803240 @default.
• W2011128550 hasConceptScore W2011128550C89423630 @default.
• W2011128550 hasIssue "1" @default.
• W2011128550 hasLocation W20111285501 @default.
• W2011128550 hasLocation W20111285502 @default.
• W2011128550 hasOpenAccess W2011128550 @default.
• W2011128550 hasPrimaryLocation W20111285501 @default.
• W2011128550 hasRelatedWork W1986415591 @default.
• W2011128550 hasRelatedWork W2006416824 @default.
• W2011128550 hasRelatedWork W2011128550 @default.
• W2011128550 hasRelatedWork W2108371323 @default.

• next