Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011163384> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2011163384 endingPage "286" @default.
- W2011163384 startingPage "278" @default.
- W2011163384 abstract "This study was performed to examine if the cytokines interleukin-1 (IL-1), interleukin-6 (IL-6) or tumor necrosis factor (TNF) are released from the gastric mucosa during acute mucosal damage, and if the generation of these cytokines is affected by indomethacin. Cat stomachs were exposed to 2 M NaCl for 10 min followed by luminal perfusion at pH 1. Gastric mucosal blood flow was determined by radioactive microspheres, portal vein blood flow by transit-time flowmetry, and H+ back diffusion/secretion by pH-stat titration. Concentrations of active cytokines and of histamine in aortic and portal vein blood were measured by bioassay and RIA, respectively. Active IL-6, but not IL-1 and TNF, is released from the gastric mucosa during acute mucosal damage by 2 M NaCl and acid back diffusion. Indomethacin increased mucosal injury and enhanced the TNF generation but reduced the release of IL-6 from the gastric mucosa. We conclude that IL-1 and TNF probably do not play an important modulating role during acute gastric mucosal damage. The generation of IL-6 may, however, contribute to mucosal protection." @default.
- W2011163384 created "2016-06-24" @default.
- W2011163384 creator A5004471600 @default.
- W2011163384 creator A5046633770 @default.
- W2011163384 creator A5058012748 @default.
- W2011163384 date "1996-01-01" @default.
- W2011163384 modified "2023-09-28" @default.
- W2011163384 title "Release of Cytokines Associated with Gastric Mucosal Injury" @default.
- W2011163384 doi "https://doi.org/10.1159/000129467" @default.
- W2011163384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8813652" @default.
- W2011163384 hasPublicationYear "1996" @default.
- W2011163384 type Work @default.
- W2011163384 sameAs 2011163384 @default.
- W2011163384 citedByCount "15" @default.
- W2011163384 countsByYear W20111633842013 @default.
- W2011163384 countsByYear W20111633842014 @default.
- W2011163384 countsByYear W20111633842016 @default.
- W2011163384 countsByYear W20111633842018 @default.
- W2011163384 countsByYear W20111633842021 @default.
- W2011163384 crossrefType "journal-article" @default.
- W2011163384 hasAuthorship W2011163384A5004471600 @default.
- W2011163384 hasAuthorship W2011163384A5046633770 @default.
- W2011163384 hasAuthorship W2011163384A5058012748 @default.
- W2011163384 hasConcept C1122143 @default.
- W2011163384 hasConcept C126322002 @default.
- W2011163384 hasConcept C142724271 @default.
- W2011163384 hasConcept C146957229 @default.
- W2011163384 hasConcept C17991360 @default.
- W2011163384 hasConcept C2778690821 @default.
- W2011163384 hasConcept C2779422922 @default.
- W2011163384 hasConcept C2781443798 @default.
- W2011163384 hasConcept C71924100 @default.
- W2011163384 hasConcept C74172505 @default.
- W2011163384 hasConceptScore W2011163384C1122143 @default.
- W2011163384 hasConceptScore W2011163384C126322002 @default.
- W2011163384 hasConceptScore W2011163384C142724271 @default.
- W2011163384 hasConceptScore W2011163384C146957229 @default.
- W2011163384 hasConceptScore W2011163384C17991360 @default.
- W2011163384 hasConceptScore W2011163384C2778690821 @default.
- W2011163384 hasConceptScore W2011163384C2779422922 @default.
- W2011163384 hasConceptScore W2011163384C2781443798 @default.
- W2011163384 hasConceptScore W2011163384C71924100 @default.
- W2011163384 hasConceptScore W2011163384C74172505 @default.
- W2011163384 hasIssue "4" @default.
- W2011163384 hasLocation W20111633841 @default.
- W2011163384 hasLocation W20111633842 @default.
- W2011163384 hasOpenAccess W2011163384 @default.
- W2011163384 hasPrimaryLocation W20111633841 @default.
- W2011163384 hasRelatedWork W2003284009 @default.
- W2011163384 hasRelatedWork W2003952808 @default.
- W2011163384 hasRelatedWork W2051048471 @default.
- W2011163384 hasRelatedWork W2059268968 @default.
- W2011163384 hasRelatedWork W2069284309 @default.
- W2011163384 hasRelatedWork W2097636587 @default.
- W2011163384 hasRelatedWork W2262573558 @default.
- W2011163384 hasRelatedWork W2308820726 @default.
- W2011163384 hasRelatedWork W2474380429 @default.
- W2011163384 hasRelatedWork W2056390088 @default.
- W2011163384 hasVolume "28" @default.
- W2011163384 isParatext "false" @default.
- W2011163384 isRetracted "false" @default.
- W2011163384 magId "2011163384" @default.
- W2011163384 workType "article" @default.