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• W2011182234 abstract "This study focused on the expression pattern and clinical significance of B7-H3 expression in human acute leukemia.We systematically analyzed 134 patients with acute myeloid leukemia (101 cases) and acute lymphocytic leukemia (33 cases) by flow cytometry.The frequency of B7-H3(+) cases was 44.8% in total. The B7-H3 expression rate differed from 0% to 74.8% in individual cases. The correlation between B7-H3 expression and traditional prognostic factors, such as age and gender, the white blood cell count was not confirmed. However, B7-H3 had a significant higher expression in CD34(+) cases and high risk karyotypes.Owing to the expression of B7-H3 being statistically relevant in predicting disease progression and a shorter life survival, our results demonstrated that B7-H3 expression in acute leukemia predicts an unfavorable outcome." @default.
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• W2011182234 date "2014-08-16" @default.
• W2011182234 modified "2023-10-16" @default.
• W2011182234 title "Expression of costimulatory molecule B7-H3 and its prognostic implications in human acute leukemia" @default.
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• W2011182234 doi "https://doi.org/10.1179/1607845414y.0000000186" @default.
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