FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011193809> ?p ?o ?g. }

• W2011193809 abstract "Abstract The uptake of 125 I- 5 -iodo-2′-deoxy-uridine ( 125 IUdR) by lymphoma cells is inhibited in lethally irradiated hosts incompatible for Hh (hemopoietic-histocompatibility) loci. In the course of attempts to reproduce this phenomenon in vitro , a soluble factor (uptake inhibiting factor, or UIF) was found in the supernatant of cultured ( 16 hr, 37°C ) spleen cells. UIF was produced by non-stimulated splenocytes of various strains of conventional and athymic (nude) mice and rats and by various tumor lines as well. UIF was found to be non-strain, non-species and non-tissue specific, since it was capable of inhibiting the 125 IUdR uptake of mouse, hamster and human tumor cells of various tissue origins. Lethal irradiation, silica or IDF (immunodepressive factor) treatment of donor mice, or irradiation or treatment with actinomycin D of spleen cells in vitro , did not prevent UIF production by such cells. On the other hand 5 -fluoro- 2 ′-deoxy-uridine (FUdR) reduced UIF production by 50% . UIF was found to be relatively resistant to heat and proteolytic enzymes in vitro . In addition UIF was capable of cytostatic or cytotoxic effects on tumor cells in tissue culture. UIF-like activity was found also in the plasma of tumor bearing mice. The biological role of UIF seems to be uncertain. Nevertheless it could interfere markedly with in vitro assays involving cell proliferation monitored by DNA-precursor uptake." @default.
• W2011193809 created "2016-06-24" @default.
• W2011193809 creator A5001694732 @default.
• W2011193809 creator A5024871281 @default.
• W2011193809 creator A5028738361 @default.
• W2011193809 creator A5038291889 @default.
• W2011193809 creator A5062973091 @default.
• W2011193809 creator A5040662610 @default.
• W2011193809 date "1978-04-01" @default.
• W2011193809 modified "2023-09-26" @default.
• W2011193809 title "Soluble factors produced by normal or tumor cells, inhibiting the uptake of 5-iodo-2′-deoxy-uridine by cancer cells in vitro" @default.
• W2011193809 cites W1492426570 @default.
• W2011193809 cites W1497436334 @default.
• W2011193809 cites W1504147323 @default.
• W2011193809 cites W1555094581 @default.
• W2011193809 cites W1555958467 @default.
• W2011193809 cites W1585501713 @default.
• W2011193809 cites W1595585329 @default.
• W2011193809 cites W1862720865 @default.
• W2011193809 cites W1963501945 @default.
• W2011193809 cites W1978488066 @default.
• W2011193809 cites W1990035666 @default.
• W2011193809 cites W1992919859 @default.
• W2011193809 cites W2009544186 @default.
• W2011193809 cites W2019341074 @default.
• W2011193809 cites W2021205978 @default.
• W2011193809 cites W2021377565 @default.
• W2011193809 cites W2025687870 @default.
• W2011193809 cites W2025806242 @default.
• W2011193809 cites W2038183641 @default.
• W2011193809 cites W2043566608 @default.
• W2011193809 cites W2052124211 @default.
• W2011193809 cites W2056875663 @default.
• W2011193809 cites W2061199929 @default.
• W2011193809 cites W2066270846 @default.
• W2011193809 cites W2069410334 @default.
• W2011193809 cites W2070297871 @default.
• W2011193809 cites W2076306272 @default.
• W2011193809 cites W2087141021 @default.
• W2011193809 cites W2149087076 @default.
• W2011193809 cites W2167534802 @default.
• W2011193809 cites W2411949419 @default.
• W2011193809 cites W2412875703 @default.
• W2011193809 cites W2432858736 @default.
• W2011193809 doi "https://doi.org/10.1016/0014-2964(78)90214-1" @default.
• W2011193809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/648563" @default.
• W2011193809 hasPublicationYear "1978" @default.
• W2011193809 type Work @default.
• W2011193809 sameAs 2011193809 @default.
• W2011193809 citedByCount "2" @default.
• W2011193809 crossrefType "journal-article" @default.
• W2011193809 hasAuthorship W2011193809A5001694732 @default.
• W2011193809 hasAuthorship W2011193809A5024871281 @default.
• W2011193809 hasAuthorship W2011193809A5028738361 @default.
• W2011193809 hasAuthorship W2011193809A5038291889 @default.
• W2011193809 hasAuthorship W2011193809A5040662610 @default.
• W2011193809 hasAuthorship W2011193809A5062973091 @default.
• W2011193809 hasConcept C104317684 @default.
• W2011193809 hasConcept C121608353 @default.
• W2011193809 hasConcept C153911025 @default.
• W2011193809 hasConcept C154317977 @default.
• W2011193809 hasConcept C189976730 @default.
• W2011193809 hasConcept C202751555 @default.
• W2011193809 hasConcept C2778575167 @default.
• W2011193809 hasConcept C2781259782 @default.
• W2011193809 hasConcept C502942594 @default.
• W2011193809 hasConcept C54355233 @default.
• W2011193809 hasConcept C55493867 @default.
• W2011193809 hasConcept C67705224 @default.
• W2011193809 hasConcept C81885089 @default.
• W2011193809 hasConcept C86803240 @default.
• W2011193809 hasConcept C90703135 @default.
• W2011193809 hasConcept C96232424 @default.
• W2011193809 hasConceptScore W2011193809C104317684 @default.
• W2011193809 hasConceptScore W2011193809C121608353 @default.
• W2011193809 hasConceptScore W2011193809C153911025 @default.
• W2011193809 hasConceptScore W2011193809C154317977 @default.
• W2011193809 hasConceptScore W2011193809C189976730 @default.
• W2011193809 hasConceptScore W2011193809C202751555 @default.
• W2011193809 hasConceptScore W2011193809C2778575167 @default.
• W2011193809 hasConceptScore W2011193809C2781259782 @default.
• W2011193809 hasConceptScore W2011193809C502942594 @default.
• W2011193809 hasConceptScore W2011193809C54355233 @default.
• W2011193809 hasConceptScore W2011193809C55493867 @default.
• W2011193809 hasConceptScore W2011193809C67705224 @default.
• W2011193809 hasConceptScore W2011193809C81885089 @default.
• W2011193809 hasConceptScore W2011193809C86803240 @default.
• W2011193809 hasConceptScore W2011193809C90703135 @default.
• W2011193809 hasConceptScore W2011193809C96232424 @default.
• W2011193809 hasLocation W20111938091 @default.
• W2011193809 hasLocation W20111938092 @default.
• W2011193809 hasOpenAccess W2011193809 @default.
• W2011193809 hasPrimaryLocation W20111938091 @default.
• W2011193809 hasRelatedWork W2344637265 @default.
• W2011193809 hasRelatedWork W2378785636 @default.
• W2011193809 hasRelatedWork W2578744092 @default.
• W2011193809 hasRelatedWork W2783732652 @default.
• W2011193809 hasRelatedWork W2792929645 @default.
• W2011193809 hasRelatedWork W2974647127 @default.
• W2011193809 hasRelatedWork W3049178086 @default.

• next