FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011200941> ?p ?o ?g. }

• W2011200941 endingPage "443" @default.
• W2011200941 startingPage "437" @default.
• W2011200941 abstract "The effect of valeryl salicylate (VS), an inhibitor of cyclooxygenase-1 (COX-1), was evaluated in arachidonic acid or croton oil-induced ear oedema and carrageenan-induced paw oedema in mice. Ear oedema was induced by topical administration of arachidonic acid (2mg per ear; 20 microliters) or croton oil (1mg per ear; 20 microliters) to the inner surface of the left ear and the change in the ear's thickness was measured with a precision micrometer (Fisher, USA). VS significantly inhibited the arachidonic acid ear oedema after lh at doses of 1.5-45 micrograms per ear; however, only at the dose of 45 micrograms per ear was it able to significantly reduce the croton oil-induced oedema at 6h. Paw oedema was induced by the injection of 25 microliters of 1% carrageenan into the plantar aponeurosis of the right hind paw. The oedema was evaluated at 0.5, 1, 2, 4, 24, 48 and 72h. Previously in our experiments, we observed two peaks in paw oedema formation: one at 2h, in the early phase (0-4h), and the other, occurring at 48h after carrageenan injection, in the late phase (24-72h). The pre-treatment with VS significantly reduced the paw oedema at 2h, the same effect observed with celecoxib and indomethacin treatments. At 24h, VS did not inhibit oedema but significantly increased it mainly at 48h after carrageenan injection. These results showed that VS was pharmacologically active in these models and suggest that COX-1 may participate in the early and late phases of inflammation in the models studied." @default.
• W2011200941 created "2016-06-24" @default.
• W2011200941 creator A5007160105 @default.
• W2011200941 creator A5018701176 @default.
• W2011200941 creator A5055413476 @default.
• W2011200941 creator A5090907797 @default.
• W2011200941 date "2003-11-01" @default.
• W2011200941 modified "2023-10-14" @default.
• W2011200941 title "Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice" @default.
• W2011200941 cites W1490609633 @default.
• W2011200941 cites W1494920110 @default.
• W2011200941 cites W1561747056 @default.
• W2011200941 cites W157848199 @default.
• W2011200941 cites W1597379943 @default.
• W2011200941 cites W1860085360 @default.
• W2011200941 cites W1895256094 @default.
• W2011200941 cites W1970652854 @default.
• W2011200941 cites W1984127074 @default.
• W2011200941 cites W1997364548 @default.
• W2011200941 cites W2001214229 @default.
• W2011200941 cites W2003719859 @default.
• W2011200941 cites W2008574207 @default.
• W2011200941 cites W2014664456 @default.
• W2011200941 cites W2015568023 @default.
• W2011200941 cites W2025325421 @default.
• W2011200941 cites W2033448529 @default.
• W2011200941 cites W2036488915 @default.
• W2011200941 cites W2038792169 @default.
• W2011200941 cites W2040040765 @default.
• W2011200941 cites W2043069609 @default.
• W2011200941 cites W2044986343 @default.
• W2011200941 cites W2050214050 @default.
• W2011200941 cites W2064145076 @default.
• W2011200941 cites W2070386995 @default.
• W2011200941 cites W2083748640 @default.
• W2011200941 cites W2089923844 @default.
• W2011200941 cites W2102368544 @default.
• W2011200941 cites W2111144017 @default.
• W2011200941 cites W2139031861 @default.
• W2011200941 cites W2753836698 @default.
• W2011200941 doi "https://doi.org/10.1016/s1043-6618(03)00188-9" @default.
• W2011200941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12967587" @default.
• W2011200941 hasPublicationYear "2003" @default.
• W2011200941 type Work @default.
• W2011200941 sameAs 2011200941 @default.
• W2011200941 citedByCount "22" @default.
• W2011200941 countsByYear W20112009412012 @default.
• W2011200941 countsByYear W20112009412013 @default.
• W2011200941 countsByYear W20112009412014 @default.
• W2011200941 countsByYear W20112009412015 @default.
• W2011200941 countsByYear W20112009412016 @default.
• W2011200941 crossrefType "journal-article" @default.
• W2011200941 hasAuthorship W2011200941A5007160105 @default.
• W2011200941 hasAuthorship W2011200941A5018701176 @default.
• W2011200941 hasAuthorship W2011200941A5055413476 @default.
• W2011200941 hasAuthorship W2011200941A5090907797 @default.
• W2011200941 hasConcept C126322002 @default.
• W2011200941 hasConcept C181199279 @default.
• W2011200941 hasConcept C185592680 @default.
• W2011200941 hasConcept C203014093 @default.
• W2011200941 hasConcept C2776914184 @default.
• W2011200941 hasConcept C2778078955 @default.
• W2011200941 hasConcept C2778942509 @default.
• W2011200941 hasConcept C2779689624 @default.
• W2011200941 hasConcept C2780664492 @default.
• W2011200941 hasConcept C2780886150 @default.
• W2011200941 hasConcept C2781227287 @default.
• W2011200941 hasConcept C42219234 @default.
• W2011200941 hasConcept C55493867 @default.
• W2011200941 hasConcept C71924100 @default.
• W2011200941 hasConcept C98274493 @default.
• W2011200941 hasConceptScore W2011200941C126322002 @default.
• W2011200941 hasConceptScore W2011200941C181199279 @default.
• W2011200941 hasConceptScore W2011200941C185592680 @default.
• W2011200941 hasConceptScore W2011200941C203014093 @default.
• W2011200941 hasConceptScore W2011200941C2776914184 @default.
• W2011200941 hasConceptScore W2011200941C2778078955 @default.
• W2011200941 hasConceptScore W2011200941C2778942509 @default.
• W2011200941 hasConceptScore W2011200941C2779689624 @default.
• W2011200941 hasConceptScore W2011200941C2780664492 @default.
• W2011200941 hasConceptScore W2011200941C2780886150 @default.
• W2011200941 hasConceptScore W2011200941C2781227287 @default.
• W2011200941 hasConceptScore W2011200941C42219234 @default.
• W2011200941 hasConceptScore W2011200941C55493867 @default.
• W2011200941 hasConceptScore W2011200941C71924100 @default.
• W2011200941 hasConceptScore W2011200941C98274493 @default.
• W2011200941 hasIssue "5" @default.
• W2011200941 hasLocation W20112009411 @default.
• W2011200941 hasLocation W20112009412 @default.
• W2011200941 hasOpenAccess W2011200941 @default.
• W2011200941 hasPrimaryLocation W20112009411 @default.
• W2011200941 hasRelatedWork W1724438491 @default.
• W2011200941 hasRelatedWork W1860085360 @default.
• W2011200941 hasRelatedWork W2011200941 @default.
• W2011200941 hasRelatedWork W2024978551 @default.
• W2011200941 hasRelatedWork W2025263696 @default.
• W2011200941 hasRelatedWork W2047353740 @default.
• W2011200941 hasRelatedWork W2059947409 @default.

• next