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- W2011207579 abstract "A new and simple chemodosimetric probe L11 is utilized for the selective detection of biothiols in the presence of other relevant amino acids under physiological conditions (pH = 7.4). This eventually led to a turn-off luminescence response due to an effective photoinduced electron transfer based signaling mechanism. A comparison of the results of the fluorescence kinetic analysis and 1H NMR studies of the reaction between thiol and L11 or the analogous compound L22 revealed the role of intramolecular hydrogen bonding in activating the imine functionality towards nucleophilic addition. Such an example is not common in contemporary literature. Conventional MTT assay studies revealed that this probe (L11) has low cytotoxicity. Results of the cell imaging studies revealed that this probe was cell membrane permeable and could detect the intracellular distribution of biothiols within living HeLa cells. Furthermore, our studies with human blood plasma demonstrated the possibility of using this reagent for the quantitative optical detection of total biothiols in biological fluid. Such an example for the detection of biothiols in real biological samples is rare in the contemporary literature. These results clearly demonstrate the possibility of using this reagent in medicinal biology and diagnostic applications." @default.
- W2011207579 created "2016-06-24" @default.
- W2011207579 creator A5007586751 @default.
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- W2011207579 creator A5034129326 @default.
- W2011207579 creator A5052489930 @default.
- W2011207579 creator A5064890126 @default.
- W2011207579 date "2013-01-01" @default.
- W2011207579 modified "2023-10-16" @default.
- W2011207579 title "Designing a thiol specific fluorescent probe for possible use as a reagent for intracellular detection and estimation in blood serum: kinetic analysis to probe the role of intramolecular hydrogen bonding" @default.
- W2011207579 cites W14175241 @default.
- W2011207579 cites W1523726718 @default.
- W2011207579 cites W1601416041 @default.
- W2011207579 cites W1707275181 @default.
- W2011207579 cites W1954829482 @default.
- W2011207579 cites W1969354917 @default.
- W2011207579 cites W1970007512 @default.
- W2011207579 cites W1971341023 @default.
- W2011207579 cites W1972270814 @default.
- W2011207579 cites W1975634744 @default.
- W2011207579 cites W1980729827 @default.
- W2011207579 cites W1984743870 @default.
- W2011207579 cites W1985953764 @default.
- W2011207579 cites W1990412045 @default.
- W2011207579 cites W1991690458 @default.
- W2011207579 cites W1991845708 @default.
- W2011207579 cites W1992377286 @default.
- W2011207579 cites W1993012939 @default.
- W2011207579 cites W1993325306 @default.
- W2011207579 cites W1993570389 @default.
- W2011207579 cites W1995625520 @default.
- W2011207579 cites W1996815936 @default.
- W2011207579 cites W1998395915 @default.
- W2011207579 cites W1998408986 @default.
- W2011207579 cites W1999100689 @default.
- W2011207579 cites W2000088683 @default.
- W2011207579 cites W2003313796 @default.
- W2011207579 cites W2009031512 @default.
- W2011207579 cites W2010143106 @default.
- W2011207579 cites W2010816694 @default.
- W2011207579 cites W2012848498 @default.
- W2011207579 cites W2016601005 @default.
- W2011207579 cites W2021835855 @default.
- W2011207579 cites W2021905990 @default.
- W2011207579 cites W2023084496 @default.
- W2011207579 cites W2025607545 @default.
- W2011207579 cites W2025976054 @default.
- W2011207579 cites W2030771589 @default.
- W2011207579 cites W2038365734 @default.
- W2011207579 cites W2040349635 @default.
- W2011207579 cites W2042249621 @default.
- W2011207579 cites W2043912977 @default.
- W2011207579 cites W2045153676 @default.
- W2011207579 cites W2047654966 @default.
- W2011207579 cites W2049990145 @default.
- W2011207579 cites W2051240141 @default.
- W2011207579 cites W2052588755 @default.
- W2011207579 cites W2052614637 @default.
- W2011207579 cites W2055046703 @default.
- W2011207579 cites W2056313120 @default.
- W2011207579 cites W2057226312 @default.
- W2011207579 cites W2058890593 @default.
- W2011207579 cites W2061607602 @default.
- W2011207579 cites W2064041862 @default.
- W2011207579 cites W2065773831 @default.
- W2011207579 cites W2067202732 @default.
- W2011207579 cites W2070606479 @default.
- W2011207579 cites W2070805541 @default.
- W2011207579 cites W2071325560 @default.
- W2011207579 cites W2072502124 @default.
- W2011207579 cites W2073345152 @default.
- W2011207579 cites W2073588636 @default.
- W2011207579 cites W2079507386 @default.
- W2011207579 cites W2080680703 @default.
- W2011207579 cites W2087495651 @default.
- W2011207579 cites W2087762173 @default.
- W2011207579 cites W2089146883 @default.
- W2011207579 cites W2091485486 @default.
- W2011207579 cites W2091564187 @default.
- W2011207579 cites W2094016251 @default.
- W2011207579 cites W2094430384 @default.
- W2011207579 cites W2099107808 @default.
- W2011207579 cites W2101239377 @default.
- W2011207579 cites W2108264134 @default.
- W2011207579 cites W2108317418 @default.
- W2011207579 cites W2108484297 @default.
- W2011207579 cites W2110783613 @default.
- W2011207579 cites W2111066407 @default.
- W2011207579 cites W2114740251 @default.
- W2011207579 cites W2115135910 @default.
- W2011207579 cites W2122272939 @default.
- W2011207579 cites W2124820170 @default.
- W2011207579 cites W2137001034 @default.
- W2011207579 cites W2137697952 @default.
- W2011207579 cites W2143909617 @default.
- W2011207579 cites W2148700883 @default.
- W2011207579 cites W2149734247 @default.