FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011284865> ?p ?o ?g. }

• W2011284865 endingPage "1086" @default.
• W2011284865 startingPage "1081" @default.
• W2011284865 abstract "BackgroundSentinel node biopsy (SNB) was initially conceived as excision of the first station axillary lymph node(s) (LN) identified by radioactive and/or blue dye uptake. The definition was subsequently enlarged to also include palpable lymph nodes in the vicinity of sentinel node(s) (SN). We reasoned that the excision of this combination of nodes might be best achieved by sampling the lower axilla.MethodsEach patient underwent low axillary sampling (LAS) and identification of SN in the excised specimen followed by complete axillary lymph node dissection (ALND). LAS was defined as excision of all fibrofatty tissue overlying the second digitation of serratus anterior below the intercostobrachial nerve and was carried out following a pre-operative injection of radioactive colloid and an intra-operative injection of blue dye. Blue and/or hot nodes (B&/HN) in the dissected tissue and remaining axilla, along with any palpable nodes within the sampled tissue, were defined as SN. The primary endpoint of the study was to compare false negative rates (FNR) of SN with that of LAS in predicting axillary LN status (NCT00128362).FindingsThe study was performed between March 2004 and December 2011 in 478 women with clinically node negative axilla. On histopathological evaluation the median tumor size was 2.5 cm and axillary nodal metastases were found in 34.1% of patients. The FNR of SNB (12.7%, 95% CI 8.1–19.4) and LAS (10.5%, 95% CI 6.6–16.2) were not significantly different (p = 0.56). The FNR of B&/HN alone, without palpable nodes, (29.0%, 95% CI 22.5–36.6) was significantly inferior to those of SNB (p = 0.0007) and LAS (p = 0.0003).InterpretationLAS is as accurate as SNB in predicting axillary LN status in women with clinically node negative operable breast cancer. Confining SNB procedure to excision of B&/HN, significantly increases the risk of leaving behind metastatic lymph nodes in the axilla. LAS is an effective and low cost procedure that minimizes axillary surgery and can be implemented widely.Registry Name: Clinicaltrials.gov.Registration Number: NCT00128362." @default.
• W2011284865 created "2016-06-24" @default.
• W2011284865 creator A5022310549 @default.
• W2011284865 creator A5037076092 @default.
• W2011284865 creator A5048611916 @default.
• W2011284865 creator A5050720436 @default.
• W2011284865 creator A5066365621 @default.
• W2011284865 creator A5066523060 @default.
• W2011284865 creator A5066582496 @default.
• W2011284865 creator A5067497872 @default.
• W2011284865 creator A5076171969 @default.
• W2011284865 creator A5088925041 @default.
• W2011284865 date "2013-12-01" @default.
• W2011284865 modified "2023-10-16" @default.
• W2011284865 title "Sentinel node biopsy versus low axillary sampling in women with clinically node negative operable breast cancer" @default.
• W2011284865 cites W1513547972 @default.
• W2011284865 cites W1973822018 @default.
• W2011284865 cites W1991110333 @default.
• W2011284865 cites W1999931009 @default.
• W2011284865 cites W2011108157 @default.
• W2011284865 cites W2019217329 @default.
• W2011284865 cites W2030083804 @default.
• W2011284865 cites W2033991697 @default.
• W2011284865 cites W2037376566 @default.
• W2011284865 cites W2065438886 @default.
• W2011284865 cites W2071665160 @default.
• W2011284865 cites W2085837462 @default.
• W2011284865 cites W2086899550 @default.
• W2011284865 cites W2094948207 @default.
• W2011284865 cites W2108782463 @default.
• W2011284865 cites W2112516937 @default.
• W2011284865 cites W2115527491 @default.
• W2011284865 cites W2128289832 @default.
• W2011284865 cites W2131719808 @default.
• W2011284865 cites W2142875113 @default.
• W2011284865 cites W2158349354 @default.
• W2011284865 cites W2163834939 @default.
• W2011284865 cites W2335018892 @default.
• W2011284865 cites W4229656641 @default.
• W2011284865 cites W4230358054 @default.
• W2011284865 doi "https://doi.org/10.1016/j.breast.2013.06.006" @default.
• W2011284865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23948301" @default.
• W2011284865 hasPublicationYear "2013" @default.
• W2011284865 type Work @default.
• W2011284865 sameAs 2011284865 @default.
• W2011284865 citedByCount "29" @default.
• W2011284865 countsByYear W20112848652014 @default.
• W2011284865 countsByYear W20112848652015 @default.
• W2011284865 countsByYear W20112848652016 @default.
• W2011284865 countsByYear W20112848652017 @default.
• W2011284865 countsByYear W20112848652018 @default.
• W2011284865 countsByYear W20112848652019 @default.
• W2011284865 countsByYear W20112848652020 @default.
• W2011284865 countsByYear W20112848652021 @default.
• W2011284865 countsByYear W20112848652022 @default.
• W2011284865 countsByYear W20112848652023 @default.
• W2011284865 crossrefType "journal-article" @default.
• W2011284865 hasAuthorship W2011284865A5022310549 @default.
• W2011284865 hasAuthorship W2011284865A5037076092 @default.
• W2011284865 hasAuthorship W2011284865A5048611916 @default.
• W2011284865 hasAuthorship W2011284865A5050720436 @default.
• W2011284865 hasAuthorship W2011284865A5066365621 @default.
• W2011284865 hasAuthorship W2011284865A5066523060 @default.
• W2011284865 hasAuthorship W2011284865A5066582496 @default.
• W2011284865 hasAuthorship W2011284865A5067497872 @default.
• W2011284865 hasAuthorship W2011284865A5076171969 @default.
• W2011284865 hasAuthorship W2011284865A5088925041 @default.
• W2011284865 hasBestOaLocation W20112848651 @default.
• W2011284865 hasConcept C106131492 @default.
• W2011284865 hasConcept C121608353 @default.
• W2011284865 hasConcept C126322002 @default.
• W2011284865 hasConcept C126838900 @default.
• W2011284865 hasConcept C140779682 @default.
• W2011284865 hasConcept C141071460 @default.
• W2011284865 hasConcept C142724271 @default.
• W2011284865 hasConcept C179671157 @default.
• W2011284865 hasConcept C2775934546 @default.
• W2011284865 hasConcept C2776608951 @default.
• W2011284865 hasConcept C2779720271 @default.
• W2011284865 hasConcept C2780212769 @default.
• W2011284865 hasConcept C2780849966 @default.
• W2011284865 hasConcept C2908949552 @default.
• W2011284865 hasConcept C2909835446 @default.
• W2011284865 hasConcept C31972630 @default.
• W2011284865 hasConcept C41008148 @default.
• W2011284865 hasConcept C530470458 @default.
• W2011284865 hasConcept C71924100 @default.
• W2011284865 hasConceptScore W2011284865C106131492 @default.
• W2011284865 hasConceptScore W2011284865C121608353 @default.
• W2011284865 hasConceptScore W2011284865C126322002 @default.
• W2011284865 hasConceptScore W2011284865C126838900 @default.
• W2011284865 hasConceptScore W2011284865C140779682 @default.
• W2011284865 hasConceptScore W2011284865C141071460 @default.
• W2011284865 hasConceptScore W2011284865C142724271 @default.
• W2011284865 hasConceptScore W2011284865C179671157 @default.
• W2011284865 hasConceptScore W2011284865C2775934546 @default.
• W2011284865 hasConceptScore W2011284865C2776608951 @default.
• W2011284865 hasConceptScore W2011284865C2779720271 @default.

• next