Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011293372> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2011293372 endingPage "7" @default.
- W2011293372 startingPage "55" @default.
- W2011293372 abstract "Our previous studies demonstrated that estrogen (E2) prevents the development of disuse atrophy of the femur in tail-suspended rats. To elucidate the mechanisms of this E2 action, we investigated the effects of E2 on the expression of alkaline phosphatase (ALP, a marker for bone formation) and tartrate-resistant acid phosphatase (TRAP, a marker for bone resorption) in the femur of ovariectomized and tail-suspended rats. One group of ovariectomized rats received estradiol dipropionate (OVX-E2), and the other the vehicle alone (OVX). Each group was subjected to tail-suspension. After 1, 3, 5 or 7 days of suspension, ALP and TRAP mRNA levels were determined by Northern blot analysis. The ALP mRNA level was not altered by suspension in the OVX group, but it gradually increased in the OVX-E2 group, the highest level being observed at day 5 of suspension. In contrast, TRAP mRNA significantly increased at days 5 and 7 in the OVX group, while it is decreased significantly from day 3 to 7 in the OVX-E2 group. These results indicate that E2 prevents disuse atrophy of the femur in an ovariectomized and tail-suspended rat model by stimulating bone formation and by inhibiting bone resorption." @default.
- W2011293372 created "2016-06-24" @default.
- W2011293372 creator A5016437457 @default.
- W2011293372 creator A5018403874 @default.
- W2011293372 creator A5024856356 @default.
- W2011293372 creator A5030162924 @default.
- W2011293372 creator A5043701711 @default.
- W2011293372 creator A5067991157 @default.
- W2011293372 date "2001-12-01" @default.
- W2011293372 modified "2023-09-23" @default.
- W2011293372 title "Changes in mRNA levels of alkaline phosphatase and tartrate-resistant acid phosphatase in femur of ovariectomized rats: effects of estrogen and unloading." @default.
- W2011293372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12353533" @default.
- W2011293372 hasPublicationYear "2001" @default.
- W2011293372 type Work @default.
- W2011293372 sameAs 2011293372 @default.
- W2011293372 citedByCount "3" @default.
- W2011293372 countsByYear W20112933722018 @default.
- W2011293372 crossrefType "journal-article" @default.
- W2011293372 hasAuthorship W2011293372A5016437457 @default.
- W2011293372 hasAuthorship W2011293372A5018403874 @default.
- W2011293372 hasAuthorship W2011293372A5024856356 @default.
- W2011293372 hasAuthorship W2011293372A5030162924 @default.
- W2011293372 hasAuthorship W2011293372A5043701711 @default.
- W2011293372 hasAuthorship W2011293372A5067991157 @default.
- W2011293372 hasConcept C126322002 @default.
- W2011293372 hasConcept C134018914 @default.
- W2011293372 hasConcept C146562846 @default.
- W2011293372 hasConcept C151730666 @default.
- W2011293372 hasConcept C160160445 @default.
- W2011293372 hasConcept C180675623 @default.
- W2011293372 hasConcept C181199279 @default.
- W2011293372 hasConcept C185592680 @default.
- W2011293372 hasConcept C21547065 @default.
- W2011293372 hasConcept C2776541429 @default.
- W2011293372 hasConcept C2776886416 @default.
- W2011293372 hasConcept C2777164284 @default.
- W2011293372 hasConcept C2780554211 @default.
- W2011293372 hasConcept C55493867 @default.
- W2011293372 hasConcept C673006 @default.
- W2011293372 hasConcept C71924100 @default.
- W2011293372 hasConcept C8264082 @default.
- W2011293372 hasConcept C86803240 @default.
- W2011293372 hasConceptScore W2011293372C126322002 @default.
- W2011293372 hasConceptScore W2011293372C134018914 @default.
- W2011293372 hasConceptScore W2011293372C146562846 @default.
- W2011293372 hasConceptScore W2011293372C151730666 @default.
- W2011293372 hasConceptScore W2011293372C160160445 @default.
- W2011293372 hasConceptScore W2011293372C180675623 @default.
- W2011293372 hasConceptScore W2011293372C181199279 @default.
- W2011293372 hasConceptScore W2011293372C185592680 @default.
- W2011293372 hasConceptScore W2011293372C21547065 @default.
- W2011293372 hasConceptScore W2011293372C2776541429 @default.
- W2011293372 hasConceptScore W2011293372C2776886416 @default.
- W2011293372 hasConceptScore W2011293372C2777164284 @default.
- W2011293372 hasConceptScore W2011293372C2780554211 @default.
- W2011293372 hasConceptScore W2011293372C55493867 @default.
- W2011293372 hasConceptScore W2011293372C673006 @default.
- W2011293372 hasConceptScore W2011293372C71924100 @default.
- W2011293372 hasConceptScore W2011293372C8264082 @default.
- W2011293372 hasConceptScore W2011293372C86803240 @default.
- W2011293372 hasIssue "2" @default.
- W2011293372 hasLocation W20112933721 @default.
- W2011293372 hasOpenAccess W2011293372 @default.
- W2011293372 hasPrimaryLocation W20112933721 @default.
- W2011293372 hasRelatedWork W1912315874 @default.
- W2011293372 hasRelatedWork W2011293372 @default.
- W2011293372 hasRelatedWork W2037154438 @default.
- W2011293372 hasRelatedWork W2045496512 @default.
- W2011293372 hasRelatedWork W2074405142 @default.
- W2011293372 hasRelatedWork W2078431602 @default.
- W2011293372 hasRelatedWork W2367679007 @default.
- W2011293372 hasRelatedWork W2370567452 @default.
- W2011293372 hasRelatedWork W2378600321 @default.
- W2011293372 hasRelatedWork W2392163602 @default.
- W2011293372 hasVolume "45" @default.
- W2011293372 isParatext "false" @default.
- W2011293372 isRetracted "false" @default.
- W2011293372 magId "2011293372" @default.
- W2011293372 workType "article" @default.