FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011296790> ?p ?o ?g. }

• W2011296790 endingPage "2256" @default.
• W2011296790 startingPage "2250" @default.
• W2011296790 abstract "In our previous study, fluoride ([AlF4]−) disturbed ER-to-Golgi transport through the activation of ER-resident heterotrimeric G protein (ER-G protein). Therefore, ER-G protein may be implicated in ER-to-Golgi transport at the early stage prior to coat protein assembly. Sar1 translocation onto the endoplasmic reticulum (ER) membrane is suppressed by non-selective protein kinase inhibitor H89, suggesting the participation of H89-sensitive kinase in this process. To investigate the involvement of ER-G protein in ER-to-Golgi transport, the effect of Gi protein activator (mastoparan 7) was examined on Sar1 translocation onto the ER in a cell-free system consisting of microsome membrane and cytosol. Sar1 translocation onto the microsome membrane was induced by addition of GTPγS in the cell-free system. Translocation of Sar1 by GTPγS was suppressed significantly by both H89 and mastoparan 7. Mastoparan 7 suppressed the translocation of Sar1 onto the microsome membrane with dosage dependency, but mastoparan 17, the inactive analog of mastoparan 7, had no effect on Sar1 translocation. The suppressive effect of mastoparan 7 was recovered by treatment with pertussis toxin (IAP). Moreover, Gi2 protein was detected on the microsome membrane by western blotting for heterotrimeric Gi proteins. These results indicate that ER-Gi2 protein modulated Sar1 translocation onto the ER, suggesting that ER-resident Gi2 protein is an important negative regulator of vesicular transport at the early stage of vesicle formation before coat protein assembly on the ER. J. Cell. Biochem. 112: 2250–2256, 2011. © 2011 Wiley-Liss, Inc." @default.
• W2011296790 created "2016-06-24" @default.
• W2011296790 creator A5008012179 @default.
• W2011296790 creator A5023722445 @default.
• W2011296790 creator A5026192129 @default.
• W2011296790 creator A5057986577 @default.
• W2011296790 creator A5076947828 @default.
• W2011296790 creator A5081897972 @default.
• W2011296790 creator A5085258127 @default.
• W2011296790 date "2011-08-18" @default.
• W2011296790 modified "2023-09-26" @default.
• W2011296790 title "ER-resident Gi2protein controls sar1 translocation onto the ER during budding of transport vesicles" @default.
• W2011296790 cites W1498793897 @default.
• W2011296790 cites W1971476311 @default.
• W2011296790 cites W1978506057 @default.
• W2011296790 cites W1984005757 @default.
• W2011296790 cites W1985700603 @default.
• W2011296790 cites W1989092000 @default.
• W2011296790 cites W1989321171 @default.
• W2011296790 cites W1990034450 @default.
• W2011296790 cites W2000491758 @default.
• W2011296790 cites W2003123776 @default.
• W2011296790 cites W2008013667 @default.
• W2011296790 cites W2014578258 @default.
• W2011296790 cites W2016417523 @default.
• W2011296790 cites W2017451004 @default.
• W2011296790 cites W2020212296 @default.
• W2011296790 cites W2020269189 @default.
• W2011296790 cites W2029152767 @default.
• W2011296790 cites W2031750572 @default.
• W2011296790 cites W2034205721 @default.
• W2011296790 cites W2035124140 @default.
• W2011296790 cites W2037026086 @default.
• W2011296790 cites W2053279473 @default.
• W2011296790 cites W2055770178 @default.
• W2011296790 cites W2064916160 @default.
• W2011296790 cites W2065365365 @default.
• W2011296790 cites W2067480948 @default.
• W2011296790 cites W2070696414 @default.
• W2011296790 cites W2071896628 @default.
• W2011296790 cites W2072269883 @default.
• W2011296790 cites W2076519323 @default.
• W2011296790 cites W2086284430 @default.
• W2011296790 cites W2093102610 @default.
• W2011296790 cites W2097020042 @default.
• W2011296790 cites W2098880330 @default.
• W2011296790 cites W2104360518 @default.
• W2011296790 cites W2106141363 @default.
• W2011296790 cites W2110927520 @default.
• W2011296790 cites W2112456230 @default.
• W2011296790 cites W2123090385 @default.
• W2011296790 cites W2131441008 @default.
• W2011296790 cites W2132901311 @default.
• W2011296790 cites W2151942681 @default.
• W2011296790 cites W2155378301 @default.
• W2011296790 doi "https://doi.org/10.1002/jcb.23142" @default.
• W2011296790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21480366" @default.
• W2011296790 hasPublicationYear "2011" @default.
• W2011296790 type Work @default.
• W2011296790 sameAs 2011296790 @default.
• W2011296790 citedByCount "4" @default.
• W2011296790 countsByYear W20112967902012 @default.
• W2011296790 countsByYear W20112967902017 @default.
• W2011296790 crossrefType "journal-article" @default.
• W2011296790 hasAuthorship W2011296790A5008012179 @default.
• W2011296790 hasAuthorship W2011296790A5023722445 @default.
• W2011296790 hasAuthorship W2011296790A5026192129 @default.
• W2011296790 hasAuthorship W2011296790A5057986577 @default.
• W2011296790 hasAuthorship W2011296790A5076947828 @default.
• W2011296790 hasAuthorship W2011296790A5081897972 @default.
• W2011296790 hasAuthorship W2011296790A5085258127 @default.
• W2011296790 hasConcept C104317684 @default.
• W2011296790 hasConcept C119062480 @default.
• W2011296790 hasConcept C11960822 @default.
• W2011296790 hasConcept C130316041 @default.
• W2011296790 hasConcept C138626823 @default.
• W2011296790 hasConcept C139407321 @default.
• W2011296790 hasConcept C158617107 @default.
• W2011296790 hasConcept C167019083 @default.
• W2011296790 hasConcept C185592680 @default.
• W2011296790 hasConcept C2778492296 @default.
• W2011296790 hasConcept C41625074 @default.
• W2011296790 hasConcept C46617944 @default.
• W2011296790 hasConcept C55493867 @default.
• W2011296790 hasConcept C57581600 @default.
• W2011296790 hasConcept C62478195 @default.
• W2011296790 hasConcept C6492254 @default.
• W2011296790 hasConcept C80631254 @default.
• W2011296790 hasConcept C86803240 @default.
• W2011296790 hasConcept C95444343 @default.
• W2011296790 hasConcept C97029542 @default.
• W2011296790 hasConceptScore W2011296790C104317684 @default.
• W2011296790 hasConceptScore W2011296790C119062480 @default.
• W2011296790 hasConceptScore W2011296790C11960822 @default.
• W2011296790 hasConceptScore W2011296790C130316041 @default.
• W2011296790 hasConceptScore W2011296790C138626823 @default.
• W2011296790 hasConceptScore W2011296790C139407321 @default.
• W2011296790 hasConceptScore W2011296790C158617107 @default.

• next