FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011302913> ?p ?o ?g. }

• W2011302913 abstract "Abstract Background: Diarrhoeal disease is one of the major causes of morbidity and mortality in under five children. Worldwide, there are about 1.3 million under five children deaths attributable to diarrhea. Health status in Ethiopia is one of the lowest in the world with estimated health service coverage of 60%; and diarrhoeal disease remains one of the major causes of under five morbidity and mortality. Treatment with ORS does not affect the duration and severity of diarrhoea, hence acceptance of ORS is low and diarrhoea still remains the major cause of child morbidity and mortality. Diarrhoea is a commonly associated problem in children with Zinc deficiency and also leads to excess zinc losses. Objective: To assess variations in the usage of antimicrobial and/or antidiarreals in children with acute watery diarrhoea randomized to receive zinc supplementation as compared to those who do not receive it; and assess the adherence to zinc supplementation given with ORS in the management of an episode of acute watery diarrhoea. Methodology: This is part of a multicentre, multi-disciplinary, randomized and open effectiveness trial conducted in out-patient settings in Addis Ababa, Black Lion Hospital at the Department of Paediatrics. The sample size has been calculated for a two-tailed alpha of 0.05 and power of 0.2. Children aged 2-59 months and who presented with acute watery diarrhoea for less than 7 days were recruited. Results: There were 188 children randomized to the Zinc plus ORS arm and 226 children to the ORS arm. There were 193 (46.6%) females and 221 (53.4%) males. Fifty two percent of the cases were between 2-11 months of age and decreasing trend of proportion of older children was observed in the study population (P=0.0001). Zinc adherence rate was 95%. Seventy three (39.3%) patients from Zinc + ORS group and 71 (32.3%) patients from ORS group took ORS when they came for the first follow up visit (P-value=0.115). From the total study subjects 16.1% took antibiotic or antidiarhael tablets before randomization which was significantly higher than the second follow up visit observation with only 1.7% (P=0.0001). Only 3 (1.7%) patients from Zinc arm and 4 (1.8%) patients from ORS arms took antibiotic/anti diarrhoeal on the second follow up visits. Conclusion: Proper counselling of care takers significantly reduces unnecessary use of antibiotic/anti diarrhoea drugs in the treatment of childhood diarrhoea. Zinc supplementation in the treatment of childhood diarrhoea is well tolerated by patients and there is good compliance of care takers. However, we could not observe any significant difference in antibiotic/antidiarheal drug use between ORS and ORS plus Zinc groups. [Ethiop.J.Health Dev. 2008;22(2):187-190]" @default.
• W2011302913 created "2016-06-24" @default.
• W2011302913 creator A5024750771 @default.
• W2011302913 creator A5039988069 @default.
• W2011302913 creator A5070157177 @default.
• W2011302913 date "2009-02-04" @default.
• W2011302913 modified "2023-09-26" @default.
• W2011302913 title "Effect of zinc supplementation in treatment of acute diarrhea among 2-59 months children treated in Black Lion Hospital, Addis Ababa, Ethiopia" @default.
• W2011302913 cites W1513247326 @default.
• W2011302913 cites W158406059 @default.
• W2011302913 cites W1614524975 @default.
• W2011302913 cites W1896984587 @default.
• W2011302913 cites W1967523960 @default.
• W2011302913 cites W1986139763 @default.
• W2011302913 cites W1990667477 @default.
• W2011302913 cites W2028125300 @default.
• W2011302913 cites W2088554402 @default.
• W2011302913 cites W2100235164 @default.
• W2011302913 cites W2128933040 @default.
• W2011302913 doi "https://doi.org/10.4314/ejhd.v22i2.10070" @default.
• W2011302913 hasPublicationYear "2009" @default.
• W2011302913 type Work @default.
• W2011302913 sameAs 2011302913 @default.
• W2011302913 citedByCount "5" @default.
• W2011302913 countsByYear W20113029132013 @default.
• W2011302913 countsByYear W20113029132014 @default.
• W2011302913 countsByYear W20113029132015 @default.
• W2011302913 crossrefType "journal-article" @default.
• W2011302913 hasAuthorship W2011302913A5024750771 @default.
• W2011302913 hasAuthorship W2011302913A5039988069 @default.
• W2011302913 hasAuthorship W2011302913A5070157177 @default.
• W2011302913 hasBestOaLocation W20113029131 @default.
• W2011302913 hasConcept C126322002 @default.
• W2011302913 hasConcept C138816342 @default.
• W2011302913 hasConcept C159110408 @default.
• W2011302913 hasConcept C187212893 @default.
• W2011302913 hasConcept C2779802037 @default.
• W2011302913 hasConcept C3019834005 @default.
• W2011302913 hasConcept C556039675 @default.
• W2011302913 hasConcept C71924100 @default.
• W2011302913 hasConcept C99454951 @default.
• W2011302913 hasConceptScore W2011302913C126322002 @default.
• W2011302913 hasConceptScore W2011302913C138816342 @default.
• W2011302913 hasConceptScore W2011302913C159110408 @default.
• W2011302913 hasConceptScore W2011302913C187212893 @default.
• W2011302913 hasConceptScore W2011302913C2779802037 @default.
• W2011302913 hasConceptScore W2011302913C3019834005 @default.
• W2011302913 hasConceptScore W2011302913C556039675 @default.
• W2011302913 hasConceptScore W2011302913C71924100 @default.
• W2011302913 hasConceptScore W2011302913C99454951 @default.
• W2011302913 hasIssue "2" @default.
• W2011302913 hasLocation W20113029131 @default.
• W2011302913 hasOpenAccess W2011302913 @default.
• W2011302913 hasPrimaryLocation W20113029131 @default.
• W2011302913 hasRelatedWork W1519540955 @default.
• W2011302913 hasRelatedWork W1915195247 @default.
• W2011302913 hasRelatedWork W1985280691 @default.
• W2011302913 hasRelatedWork W2416767700 @default.
• W2011302913 hasRelatedWork W2914242697 @default.
• W2011302913 hasRelatedWork W3125131478 @default.
• W2011302913 hasRelatedWork W3137257752 @default.
• W2011302913 hasRelatedWork W4232113911 @default.
• W2011302913 hasRelatedWork W4241097762 @default.
• W2011302913 hasRelatedWork W4285678566 @default.
• W2011302913 hasVolume "22" @default.
• W2011302913 isParatext "false" @default.
• W2011302913 isRetracted "false" @default.
• W2011302913 magId "2011302913" @default.
• W2011302913 workType "article" @default.