Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011314897> ?p ?o ?g. }
- W2011314897 endingPage "4881" @default.
- W2011314897 startingPage "4865" @default.
- W2011314897 abstract "The neurohypophyseal hormones vasopressin and oxytocin are produced and released within the mammalian brain, where they act via multiple receptor subtypes. The neural distributions of these receptors, for example, V1a and oxytocin receptors, have been well described in many mammals. In birds, the distribution of binding sites for the homologous neuropeptides, vasotocin (VT) and mesotocin, has been studied in several species by using synthetic radioligands designed to bind to mammalian receptors. Such binding studies, however, may not reveal the specific distributions of each receptor subtype. To identify and map the receptors likely to bind VT and mesotocin, we generated partial cDNA sequences for four VT receptor subtypes, VT1, VT2 (V1b), VT3 (oxytocin-like), and VT4 (V1a), in white-throated sparrow (Zonotrichia albicollis) and zebra finch (Taeniopygia guttata). These genes shared high sequence identity with the homologous avian and mammalian neurohypophyseal peptide receptors, and we found evidence for VT1, VT3, and VT4 receptor mRNA expression throughout the brains of both species. As has been described in rodents, there was striking interspecific and intraspecific variation in the densities and distribution of these receptors. For example, whereas the VT1 receptor mRNA was more widespread in zebra finch brain, the VT3 (oxytocin-like) receptor mRNA was more prevalent in the sparrow brain. Although VT2 (V1b) receptor mRNA was abundant in the pituitary, it was not found in the brain. Because of their association with brain regions implicated in social behavior, the VT1, VT3, and VT4 receptors are all likely candidates for mediating the behavioral effects of VT." @default.
- W2011314897 created "2016-06-24" @default.
- W2011314897 creator A5004225641 @default.
- W2011314897 creator A5022046931 @default.
- W2011314897 creator A5026373043 @default.
- W2011314897 creator A5032196773 @default.
- W2011314897 creator A5044839995 @default.
- W2011314897 creator A5046884490 @default.
- W2011314897 creator A5051652362 @default.
- W2011314897 date "2011-11-15" @default.
- W2011314897 modified "2023-10-16" @default.
- W2011314897 title "Neural Distribution of Vasotocin Receptor mRNA in Two Species of Songbird" @default.
- W2011314897 cites W1511351296 @default.
- W2011314897 cites W1538837544 @default.
- W2011314897 cites W1556396873 @default.
- W2011314897 cites W1611946656 @default.
- W2011314897 cites W1866285812 @default.
- W2011314897 cites W1917460858 @default.
- W2011314897 cites W1968660884 @default.
- W2011314897 cites W1968677163 @default.
- W2011314897 cites W1969366595 @default.
- W2011314897 cites W1969375325 @default.
- W2011314897 cites W1969526687 @default.
- W2011314897 cites W1975747775 @default.
- W2011314897 cites W1977151065 @default.
- W2011314897 cites W1978390724 @default.
- W2011314897 cites W1979334943 @default.
- W2011314897 cites W1979933686 @default.
- W2011314897 cites W1983029715 @default.
- W2011314897 cites W1984682174 @default.
- W2011314897 cites W1987523030 @default.
- W2011314897 cites W1987892752 @default.
- W2011314897 cites W1988622462 @default.
- W2011314897 cites W1988686168 @default.
- W2011314897 cites W1991710862 @default.
- W2011314897 cites W1992677935 @default.
- W2011314897 cites W1992729034 @default.
- W2011314897 cites W1997758712 @default.
- W2011314897 cites W1998008498 @default.
- W2011314897 cites W1998069324 @default.
- W2011314897 cites W1998107589 @default.
- W2011314897 cites W2000542029 @default.
- W2011314897 cites W2001653632 @default.
- W2011314897 cites W2002855569 @default.
- W2011314897 cites W2005204981 @default.
- W2011314897 cites W2006671469 @default.
- W2011314897 cites W2007086728 @default.
- W2011314897 cites W2008019502 @default.
- W2011314897 cites W2008384079 @default.
- W2011314897 cites W2010459044 @default.
- W2011314897 cites W2010947855 @default.
- W2011314897 cites W2011415433 @default.
- W2011314897 cites W2013428862 @default.
- W2011314897 cites W2013894378 @default.
- W2011314897 cites W2014628136 @default.
- W2011314897 cites W2015040514 @default.
- W2011314897 cites W2015669676 @default.
- W2011314897 cites W2016693654 @default.
- W2011314897 cites W2018286686 @default.
- W2011314897 cites W2019587164 @default.
- W2011314897 cites W2022927508 @default.
- W2011314897 cites W2023238302 @default.
- W2011314897 cites W2027317959 @default.
- W2011314897 cites W2027394343 @default.
- W2011314897 cites W2028924008 @default.
- W2011314897 cites W2030966943 @default.
- W2011314897 cites W2046883253 @default.
- W2011314897 cites W2047327938 @default.
- W2011314897 cites W2048033620 @default.
- W2011314897 cites W2048066331 @default.
- W2011314897 cites W2049004110 @default.
- W2011314897 cites W2049578724 @default.
- W2011314897 cites W2050620861 @default.
- W2011314897 cites W2051718288 @default.
- W2011314897 cites W2056856182 @default.
- W2011314897 cites W2058351103 @default.
- W2011314897 cites W2058901343 @default.
- W2011314897 cites W2060064765 @default.
- W2011314897 cites W2062583603 @default.
- W2011314897 cites W2068987412 @default.
- W2011314897 cites W2069735085 @default.
- W2011314897 cites W2070945109 @default.
- W2011314897 cites W2076219419 @default.
- W2011314897 cites W2076436342 @default.
- W2011314897 cites W2079222074 @default.
- W2011314897 cites W2080452670 @default.
- W2011314897 cites W2080988206 @default.
- W2011314897 cites W2082918921 @default.
- W2011314897 cites W2083325896 @default.
- W2011314897 cites W2092050340 @default.
- W2011314897 cites W2093002480 @default.
- W2011314897 cites W2093351084 @default.
- W2011314897 cites W2093571660 @default.
- W2011314897 cites W2095009288 @default.
- W2011314897 cites W2095657976 @default.
- W2011314897 cites W2098061972 @default.
- W2011314897 cites W2099487632 @default.
- W2011314897 cites W2101713116 @default.