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• W2011330202 abstract "The present data indicate that status epilepticus (SE) induced in adult rats is associated with cognitive dysfunctions and cerebral oxidative stress (OS). This has been demonstrated using lithium-pilocarpine (Li-Pc) model of SE. OS occurring in hippocampus and striatum of mature brain following SE is apparently due to both the increased free radicals production and the limited antioxidant defense. Pronounced alterations were noticed in the enzymatic, glutathione-S transferase (GST), catalase (CAT), and superoxide dismutase (SOD), as well as in the nonenzymatic; thiobarbituric acid (TBARS) and reduced glutathione (GST), indices of OS in the hippocampus and striatum of SE induced animals. Quinacrine (Qcn), proglumide (Pgm), and pentoxifylline (Ptx) administered to animals before inducing SE, were significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral OS. The findings suggest that all the drugs were effective in the order of Ptx < Pgm < Qcn indicating that these drugs are potentially antiepileptic as well as antioxidant; however, further studies are needed to establish this fact. It can be assumed that these antiepileptic substances with antioxidant properties combined with conventional therapies might provide a beneficial effect in treatment of epilepsy through ameliorating the cerebral OS." @default.
• W2011330202 created "2016-06-24" @default.
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• W2011330202 date "2014-01-01" @default.
• W2011330202 modified "2023-09-27" @default.
• W2011330202 title "The Effects of Quinacrine, Proglumide, and Pentoxifylline on Seizure Activity, Cognitive Deficit, and Oxidative Stress in Rat Lithium-Pilocarpine Model of Status Epilepticus" @default.
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• W2011330202 cites W1581414347 @default.
• W2011330202 cites W1750690213 @default.
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• W2011330202 cites W1904415054 @default.
• W2011330202 cites W1951602267 @default.
• W2011330202 cites W195697071 @default.
• W2011330202 cites W1964004644 @default.
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• W2011330202 cites W2014430418 @default.
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• W2011330202 doi "https://doi.org/10.1155/2014/630509" @default.
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