Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011343768> ?p ?o ?g. }
- W2011343768 endingPage "262" @default.
- W2011343768 startingPage "241" @default.
- W2011343768 abstract "1. Competition between two foreign nerves innervating frog skeletal muscle has been studied by using pairs of somatic motor nerves (s.m.n.s) or one s.m.n. and the preganglionic splanchnic nerve (s.p.n.) implanted into a denervated sartorius muscle that has been transplanted to the lymph sac of the back. 2. A single s.m.n. implanted into the muscle succeeded in innervating essentially every fibre within 2--3 months; tetanic stimulation of the nerve elicited 9--100% of the maximal direct tetanus tension. Most of the e.p.p.s were suprathreshold, since a single indirect stimulus evoked a twitch 60--100% as large as that to a direct stimulus. 3. If two s.m.n.s were implanted simultaneously, tetanic stimulation of either elicited 80--100% of the maximal tension to direct stimulation. If one nerve was implanted 2--3 months before the other, the second, although usually less effective than the first, normally innervated 50--100% of the fibres, with approximately the same time course of innervation as a single s.m.n. 4. Mutual synaptic repression was seen on examination of twitch tensions. With either simultaneous or staggered innervation, stimulation of each s.m.n. resulted in a twitch of 30--50% of the total direct twitch tension, with little overlap between the fields driven by the two nerves. Intracellular recordings showed that the distribution of subthreshold and spike-producing e.p.p.s reflected the existence of separate twitch fields. Even if one s.m.n. was implanted several months before the other and had time to establish suprathreshold junctions on most muscle fibres, an s.m.n. implanted later was able to reduce sharply the effectiveness of many junctions from the earlier nerve while itself innervating most muscle fibres. 5. The subthreshold e.p.p.s had low quantal content, typically ten or fewer quanta/e.p.p. The min e.p.p. frequency was very low, while min e.p.p. amplitude appeared to be normal. 6. In the vast majority of muscle fibres, junctions from the two nerves were not within recording distance of each other. Hence, we infer that the competitive interaction was mediated somehow via the muscle fibre. 7. The preganglionic splanchnic nerve, which also successfully reinnervated frog skeletal muscle, competed with a foreign s.m.n. in ways which differ qualitatively from the competition by a second s.m.n. In the presence of a s.m.n., synapses of the s.p.n. were almost universally subthreshold. However, if the s.p.n. was implanted 2--3 months before the s.m.n., the s.m.n. was prevented for several months from innervating fibres driven by the s.p.n. This delay in s.m.n. reinnervation was greater than if the first nerve implanted was also an s.m.n. 8. After 6--8 months of dual innervation by s.m.n. and s.p.n., the s.m.n. became almost totally dominant. However, if the s.m.n. was then sectioned, the s.p.n. became as effective, within approximately 1 week, as it would have been in the absence of the s.m.n." @default.
- W2011343768 created "2016-06-24" @default.
- W2011343768 creator A5035662975 @default.
- W2011343768 creator A5040274049 @default.
- W2011343768 creator A5042351184 @default.
- W2011343768 date "1979-04-01" @default.
- W2011343768 modified "2023-10-18" @default.
- W2011343768 title "Competitive interaction between foreign nerves innervating frog skeletal muscle." @default.
- W2011343768 cites W1967493235 @default.
- W2011343768 cites W1968600175 @default.
- W2011343768 cites W1969958128 @default.
- W2011343768 cites W1974332021 @default.
- W2011343768 cites W1978419856 @default.
- W2011343768 cites W1980418686 @default.
- W2011343768 cites W1981916406 @default.
- W2011343768 cites W1988081699 @default.
- W2011343768 cites W1989119181 @default.
- W2011343768 cites W1989365798 @default.
- W2011343768 cites W2001141245 @default.
- W2011343768 cites W2007860969 @default.
- W2011343768 cites W2027132353 @default.
- W2011343768 cites W2030365382 @default.
- W2011343768 cites W2039467550 @default.
- W2011343768 cites W2039955937 @default.
- W2011343768 cites W2048663426 @default.
- W2011343768 cites W2052135279 @default.
- W2011343768 cites W2056708657 @default.
- W2011343768 cites W2061452716 @default.
- W2011343768 cites W2062478860 @default.
- W2011343768 cites W2064777436 @default.
- W2011343768 cites W2070523081 @default.
- W2011343768 cites W2071169368 @default.
- W2011343768 cites W2072699258 @default.
- W2011343768 cites W2104656701 @default.
- W2011343768 cites W2112229221 @default.
- W2011343768 cites W2120994890 @default.
- W2011343768 cites W2150262991 @default.
- W2011343768 cites W2162432951 @default.
- W2011343768 cites W2329903859 @default.
- W2011343768 cites W2419926592 @default.
- W2011343768 cites W2464601534 @default.
- W2011343768 cites W2472072143 @default.
- W2011343768 cites W67679384 @default.
- W2011343768 doi "https://doi.org/10.1113/jphysiol.1979.sp012735" @default.
- W2011343768 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1281368" @default.
- W2011343768 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/222899" @default.
- W2011343768 hasPublicationYear "1979" @default.
- W2011343768 type Work @default.
- W2011343768 sameAs 2011343768 @default.
- W2011343768 citedByCount "45" @default.
- W2011343768 countsByYear W20113437682019 @default.
- W2011343768 crossrefType "journal-article" @default.
- W2011343768 hasAuthorship W2011343768A5035662975 @default.
- W2011343768 hasAuthorship W2011343768A5040274049 @default.
- W2011343768 hasAuthorship W2011343768A5042351184 @default.
- W2011343768 hasBestOaLocation W20113437682 @default.
- W2011343768 hasConcept C105702510 @default.
- W2011343768 hasConcept C112592302 @default.
- W2011343768 hasConcept C134018914 @default.
- W2011343768 hasConcept C15744967 @default.
- W2011343768 hasConcept C170493617 @default.
- W2011343768 hasConcept C185592680 @default.
- W2011343768 hasConcept C24998067 @default.
- W2011343768 hasConcept C2775912687 @default.
- W2011343768 hasConcept C2776855439 @default.
- W2011343768 hasConcept C2779918689 @default.
- W2011343768 hasConcept C2780661788 @default.
- W2011343768 hasConcept C542102704 @default.
- W2011343768 hasConcept C55493867 @default.
- W2011343768 hasConcept C6742658 @default.
- W2011343768 hasConcept C86803240 @default.
- W2011343768 hasConceptScore W2011343768C105702510 @default.
- W2011343768 hasConceptScore W2011343768C112592302 @default.
- W2011343768 hasConceptScore W2011343768C134018914 @default.
- W2011343768 hasConceptScore W2011343768C15744967 @default.
- W2011343768 hasConceptScore W2011343768C170493617 @default.
- W2011343768 hasConceptScore W2011343768C185592680 @default.
- W2011343768 hasConceptScore W2011343768C24998067 @default.
- W2011343768 hasConceptScore W2011343768C2775912687 @default.
- W2011343768 hasConceptScore W2011343768C2776855439 @default.
- W2011343768 hasConceptScore W2011343768C2779918689 @default.
- W2011343768 hasConceptScore W2011343768C2780661788 @default.
- W2011343768 hasConceptScore W2011343768C542102704 @default.
- W2011343768 hasConceptScore W2011343768C55493867 @default.
- W2011343768 hasConceptScore W2011343768C6742658 @default.
- W2011343768 hasConceptScore W2011343768C86803240 @default.
- W2011343768 hasIssue "1" @default.
- W2011343768 hasLocation W20113437681 @default.
- W2011343768 hasLocation W20113437682 @default.
- W2011343768 hasLocation W20113437683 @default.
- W2011343768 hasOpenAccess W2011343768 @default.
- W2011343768 hasPrimaryLocation W20113437681 @default.
- W2011343768 hasRelatedWork W1521025900 @default.
- W2011343768 hasRelatedWork W1966243184 @default.
- W2011343768 hasRelatedWork W2011343768 @default.
- W2011343768 hasRelatedWork W2043240910 @default.
- W2011343768 hasRelatedWork W2047734439 @default.
- W2011343768 hasRelatedWork W2059813629 @default.