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- W2011361213 abstract "In recent years there has been a growing concern regarding potential opioid effects on sleep quality. The following initial study evaluated the sleep of opioid (n = 10) and non-opioid (n = 10) using male veterans who participated in a three-week, multidisciplinary, inpatient chronic pain rehabilitation program. As part of the treatment program, objective data were obtained for daytime and nighttime activity via a watch-sized actigraphy device (Actiwatch) worn on the non-dominant wrist. The Actiwatch has demonstrated reliability and validity as a measure of general activity and sleep quality. Subjects in the opioid group were gradually withdrawn from these medications during the first two weeks of their hospital stay. Comparisons of sleep quantity (minutes) and sleep quality were made between the opioid and non-opioid groups. Statistical analyses revealed that during week one, the opioid group demonstrated poorer sleep quality and fewer minutes of sleep than the non-opioid group. In addition, the opioid group showed an improvement in sleep quality at week three when compared to week one, while the non-opioid group did not. Further analyses revealed that the results were not due to differences in daytime activity level, pain intensity, or other sedating medications. It was concluded that patients on opioid therapy experienced more sleep disturbance than those not on opioid therapy, and that withdrawal of opioid medications improved sleep quality within a short period of time. Additional study is warranted to replicate these findings, as well as expand the research regarding the relationship between opioid use and sleep disturbance. (This study was supported by an RR&D grant from the Veterans Administration.)" @default.
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- W2011361213 date "2009-04-01" @default.
- W2011361213 modified "2023-09-26" @default.
- W2011361213 title "The relationship between opioid usage and sleep quality in veterans with chronic pain syndrome" @default.
- W2011361213 doi "https://doi.org/10.1016/j.jpain.2009.01.201" @default.
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