FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011362480> ?p ?o ?g. }

• W2011362480 endingPage "1146" @default.
• W2011362480 startingPage "1137" @default.
• W2011362480 abstract "Background Continuous assessment of tissue perfusion and oxygen utilization may allow for early recognition and correction of hemorrhagic shock. We hypothesized that continuously monitoring skeletal muscle (SM) Po2, Pco2, and pH during shock would provide an easily accessible method for assessing the severity of blood loss and the efficacy of resuscitation. Methods Thirteen anesthetized pigs (25–35 kg) underwent laparotomy and femoral vessel cannulation. Multiparameter fiberoptic sensors were placed in the deltoid (SM) and femoral artery. Ventilation was maintained at a Paco2 of 40–45 mm Hg. Total blood volume (TBV) was measured using an Evans blue dye technique. Animals were bled for 15 minutes, maintained at a mean arterial pressure (MAP) of 40 mm Hg for 1 hour, resuscitated (shed blood + 2 times shed volume in normal saline) and observed for 1 hour. Four animals served as controls (sham hemorrhage). Blood and tissue samples were taken at each time point. Results Blood loss ranged from 28.5–56% of TBV. SM pH and SM Po2 levels fell rapidly with shock. SM Po2 returned to normal with resuscitation; however, SM pH did not return to baseline. SM Pco2 significantly rose with shock, but returned to baseline promptly with resuscitation. There was a significant correlation between SM pH and blood volume loss at end shock (r2 = 0.73, p < 0.001) and recovery (r2 = 0.84, p < 0.001). Animals (n = 2) whose SM pH did not recover to 7.2 were found to have ongoing blood loss from biopsy sites and persistent tissue hypercarbia despite normal MAP. Conclusion Continuous multiparameter monitoring of SM provides a minimally invasive method for assessing severity of shock and efficacy of resuscitation. Both Pco2 and Po2 levels change rapidly with shock and resuscitation. SM pH is directly proportional to lost blood volume. Persistent SM acidosis (pH < 7.2) and elevated Pco2 levels suggest incomplete resuscitation despite normalized hemodynamics." @default.
• W2011362480 created "2016-06-24" @default.
• W2011362480 creator A5025836991 @default.
• W2011362480 creator A5032509360 @default.
• W2011362480 creator A5034070362 @default.
• W2011362480 creator A5056347357 @default.
• W2011362480 creator A5056497705 @default.
• W2011362480 creator A5076653113 @default.
• W2011362480 creator A5080966900 @default.
• W2011362480 date "2001-12-01" @default.
• W2011362480 modified "2023-09-27" @default.
• W2011362480 title "Skeletal Muscle Acidosis Correlates with the Severity of Blood Volume Loss during Shock and Resuscitation" @default.
• W2011362480 cites W174568812 @default.
• W2011362480 cites W1809491479 @default.
• W2011362480 cites W1910663300 @default.
• W2011362480 cites W1969344160 @default.
• W2011362480 cites W1977597053 @default.
• W2011362480 cites W1977647194 @default.
• W2011362480 cites W1987825285 @default.
• W2011362480 cites W1987869756 @default.
• W2011362480 cites W1988793653 @default.
• W2011362480 cites W1990199366 @default.
• W2011362480 cites W2015121142 @default.
• W2011362480 cites W2015283962 @default.
• W2011362480 cites W2027790935 @default.
• W2011362480 cites W2040277963 @default.
• W2011362480 cites W2042339594 @default.
• W2011362480 cites W2043965505 @default.
• W2011362480 cites W2050259204 @default.
• W2011362480 cites W2052034425 @default.
• W2011362480 cites W2056860891 @default.
• W2011362480 cites W2068650580 @default.
• W2011362480 cites W2078148287 @default.
• W2011362480 cites W2085698477 @default.
• W2011362480 cites W2091571217 @default.
• W2011362480 cites W2093808610 @default.
• W2011362480 cites W2095135692 @default.
• W2011362480 cites W2109840536 @default.
• W2011362480 cites W2152063232 @default.
• W2011362480 cites W2156967952 @default.
• W2011362480 cites W2193732351 @default.
• W2011362480 cites W2404106741 @default.
• W2011362480 cites W2411547231 @default.
• W2011362480 cites W2413971748 @default.
• W2011362480 cites W80233590 @default.
• W2011362480 doi "https://doi.org/10.1097/00005373-200112000-00020" @default.
• W2011362480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11740266" @default.
• W2011362480 hasPublicationYear "2001" @default.
• W2011362480 type Work @default.
• W2011362480 sameAs 2011362480 @default.
• W2011362480 citedByCount "30" @default.
• W2011362480 countsByYear W20113624802012 @default.
• W2011362480 countsByYear W20113624802013 @default.
• W2011362480 countsByYear W20113624802014 @default.
• W2011362480 countsByYear W20113624802015 @default.
• W2011362480 countsByYear W20113624802017 @default.
• W2011362480 countsByYear W20113624802018 @default.
• W2011362480 countsByYear W20113624802019 @default.
• W2011362480 countsByYear W20113624802020 @default.
• W2011362480 countsByYear W20113624802022 @default.
• W2011362480 countsByYear W20113624802023 @default.
• W2011362480 crossrefType "journal-article" @default.
• W2011362480 hasAuthorship W2011362480A5025836991 @default.
• W2011362480 hasAuthorship W2011362480A5032509360 @default.
• W2011362480 hasAuthorship W2011362480A5034070362 @default.
• W2011362480 hasAuthorship W2011362480A5056347357 @default.
• W2011362480 hasAuthorship W2011362480A5056497705 @default.
• W2011362480 hasAuthorship W2011362480A5076653113 @default.
• W2011362480 hasAuthorship W2011362480A5080966900 @default.
• W2011362480 hasConcept C126322002 @default.
• W2011362480 hasConcept C141071460 @default.
• W2011362480 hasConcept C146957229 @default.
• W2011362480 hasConcept C164705383 @default.
• W2011362480 hasConcept C2777140959 @default.
• W2011362480 hasConcept C2777397205 @default.
• W2011362480 hasConcept C2778165595 @default.
• W2011362480 hasConcept C2778553927 @default.
• W2011362480 hasConcept C2779537118 @default.
• W2011362480 hasConcept C2779723990 @default.
• W2011362480 hasConcept C2781300812 @default.
• W2011362480 hasConcept C37557685 @default.
• W2011362480 hasConcept C42219234 @default.
• W2011362480 hasConcept C71924100 @default.
• W2011362480 hasConceptScore W2011362480C126322002 @default.
• W2011362480 hasConceptScore W2011362480C141071460 @default.
• W2011362480 hasConceptScore W2011362480C146957229 @default.
• W2011362480 hasConceptScore W2011362480C164705383 @default.
• W2011362480 hasConceptScore W2011362480C2777140959 @default.
• W2011362480 hasConceptScore W2011362480C2777397205 @default.
• W2011362480 hasConceptScore W2011362480C2778165595 @default.
• W2011362480 hasConceptScore W2011362480C2778553927 @default.
• W2011362480 hasConceptScore W2011362480C2779537118 @default.
• W2011362480 hasConceptScore W2011362480C2779723990 @default.
• W2011362480 hasConceptScore W2011362480C2781300812 @default.
• W2011362480 hasConceptScore W2011362480C37557685 @default.
• W2011362480 hasConceptScore W2011362480C42219234 @default.
• W2011362480 hasConceptScore W2011362480C71924100 @default.
• W2011362480 hasIssue "6" @default.

• next