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- W2011381465 abstract "1. Respiratory intrathoracic pressure variations can produce vascular pressure changes by modulating the stroke volume. 2. Rhythmic vascular pressure variations, synchronous with respiration, can also be produced by a central mechanism through changes in vasomotion and/or stroke volume (Traube oscillator). 3. Respiratory pressure variations vary in different segments of the vasculature, depending upon the physical characteristics of the vascular bed. 4. The net effect of these pressure modulations can result in vascular pressure changes exceeding intrathoracic pressure changes. This seems to be the case in patients with pulmonary hypertension. Its effect upon vascular net pressures is discussed. 5. Changes in the relation between vascular and intrathoracic pressure variations allow differentiation between ventilatory and circulatory changes in the lung. 6. During diffusion respiration, “respiratory” pressure variations can be observed both in the peripheral and pulmonary vasculature. These changes may be coupled with sinus arrhythmia, demonstrating the influence of the respiratory center upon cardiac and vasomotor activity. 7. The application of drugs during diffusion respiration demonstrates their effect upon pulmonary circulation in the absence of ventilation, and the influence of circulatory changes upon static intrapleural pressure (lung elasticity) and air exchange due to cardiac activity." @default.
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- W2011381465 date "1957-12-01" @default.
- W2011381465 modified "2023-10-17" @default.
- W2011381465 title "Some interrelations between ventilation and circulation" @default.
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- W2011381465 doi "https://doi.org/10.1016/0002-8703(57)90189-8" @default.
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