Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011393310> ?p ?o ?g. }
- W2011393310 endingPage "269" @default.
- W2011393310 startingPage "261" @default.
- W2011393310 abstract "Background: As an important mediator by which the brain receives information about the body's energy state, leptin may be associated with subjectively perceived health. Objective: The main aim of the present study was to investigate concurrent and prospective associations between leptin and self-rated health (SRH), a strong predictor of morbidity and mortality, in a random population sample. An additional aim was to examine whether sick leave was associated with leptin and poor SRH. Methods: In a prospective, population-based cohort study in Sweden, men and women underwent a medical examination in 1998, at which time blood was drawn and participants were asked to respond to a questionnaire concerning demographics, health behavior, and psychosocial factors. In 2000, the participants responded to a second questionnaire sent by postal mail. Spearman rank correlations were used to investigate the relationships between leptin, SRH, sick leave, and background variables. Partial Spearman coefficients were then calculated to investigate the patterns of association between leptin, SRH, and sick leave independent of age, body mass index (BMI), presence of diagnosis, and testosterone or estradiol. Results: A total of 98 men and 104 women, aged 23 to 76 years, and 91 men and 96 women at follow-up, participated in the study. In men, relatively higher levels of leptin were prospectively associated with relatively worse SRH (ρ = 0.20; P = 0.05), but the relationship was not significant in the cross-sectional analysis (ρ = 0.18; P = 0.07). This association was not found in women. When controlling for age, BMI, presence of diagnosis, and testosterone, higher levels of leptin were associated with poor SRH in men in cross-sectional analysis (ρ = 0.27; P < 0.01) but not prospectively. In women, leptin was not associated with SRH in cross-sectional analysis, but relatively higher levels were prospectively associated with better SRH when adjusted for background factors and estradiol (ρ = −0.26; P < 0.05). SRH was independently associated with future sick leave in both men (ρ = 0.34; P < 0.01) and women (ρ = 0.30; P < 0.05), whereas no association between leptin and future sick leave was found. Conclusions: Contrasting associations were found between men and women in the relationship between leptin and SRH. Based on the finding that higher leptin levels were associated with better SRH in women than in men, along with corroboration from recent studies, we propose that leptin may serve different psychobiological functions in men than in women." @default.
- W2011393310 created "2016-06-24" @default.
- W2011393310 creator A5009857199 @default.
- W2011393310 creator A5025808995 @default.
- W2011393310 creator A5029552599 @default.
- W2011393310 creator A5049604935 @default.
- W2011393310 creator A5051153446 @default.
- W2011393310 creator A5073745780 @default.
- W2011393310 date "2010-06-01" @default.
- W2011393310 modified "2023-09-30" @default.
- W2011393310 title "Associations between leptin and self-rated health in men and women" @default.
- W2011393310 cites W1548001373 @default.
- W2011393310 cites W1968243249 @default.
- W2011393310 cites W1968293808 @default.
- W2011393310 cites W1971389425 @default.
- W2011393310 cites W1972062612 @default.
- W2011393310 cites W1978077965 @default.
- W2011393310 cites W1994638700 @default.
- W2011393310 cites W2001585610 @default.
- W2011393310 cites W2009388360 @default.
- W2011393310 cites W2010610426 @default.
- W2011393310 cites W2015491565 @default.
- W2011393310 cites W2024568573 @default.
- W2011393310 cites W2025550733 @default.
- W2011393310 cites W2028717323 @default.
- W2011393310 cites W2041367413 @default.
- W2011393310 cites W2058073773 @default.
- W2011393310 cites W2084942467 @default.
- W2011393310 cites W2099380913 @default.
- W2011393310 cites W2099590875 @default.
- W2011393310 cites W2099974911 @default.
- W2011393310 cites W2104997591 @default.
- W2011393310 cites W2115193180 @default.
- W2011393310 cites W2121614675 @default.
- W2011393310 cites W2126960159 @default.
- W2011393310 cites W2127205066 @default.
- W2011393310 cites W2130069961 @default.
- W2011393310 cites W2142213531 @default.
- W2011393310 cites W2142823391 @default.
- W2011393310 cites W2149814390 @default.
- W2011393310 cites W4232250723 @default.
- W2011393310 cites W4235526172 @default.
- W2011393310 cites W4312243406 @default.
- W2011393310 doi "https://doi.org/10.1016/j.genm.2010.05.001" @default.
- W2011393310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20638631" @default.
- W2011393310 hasPublicationYear "2010" @default.
- W2011393310 type Work @default.
- W2011393310 sameAs 2011393310 @default.
- W2011393310 citedByCount "7" @default.
- W2011393310 countsByYear W20113933102012 @default.
- W2011393310 countsByYear W20113933102013 @default.
- W2011393310 countsByYear W20113933102018 @default.
- W2011393310 countsByYear W20113933102019 @default.
- W2011393310 countsByYear W20113933102021 @default.
- W2011393310 crossrefType "journal-article" @default.
- W2011393310 hasAuthorship W2011393310A5009857199 @default.
- W2011393310 hasAuthorship W2011393310A5025808995 @default.
- W2011393310 hasAuthorship W2011393310A5029552599 @default.
- W2011393310 hasAuthorship W2011393310A5049604935 @default.
- W2011393310 hasAuthorship W2011393310A5051153446 @default.
- W2011393310 hasAuthorship W2011393310A5073745780 @default.
- W2011393310 hasConcept C118552586 @default.
- W2011393310 hasConcept C126322002 @default.
- W2011393310 hasConcept C144024400 @default.
- W2011393310 hasConcept C149923435 @default.
- W2011393310 hasConcept C150966472 @default.
- W2011393310 hasConcept C188816634 @default.
- W2011393310 hasConcept C201903717 @default.
- W2011393310 hasConcept C2780221984 @default.
- W2011393310 hasConcept C2780613262 @default.
- W2011393310 hasConcept C2908647359 @default.
- W2011393310 hasConcept C511355011 @default.
- W2011393310 hasConcept C61470247 @default.
- W2011393310 hasConcept C71924100 @default.
- W2011393310 hasConcept C72563966 @default.
- W2011393310 hasConcept C99454951 @default.
- W2011393310 hasConceptScore W2011393310C118552586 @default.
- W2011393310 hasConceptScore W2011393310C126322002 @default.
- W2011393310 hasConceptScore W2011393310C144024400 @default.
- W2011393310 hasConceptScore W2011393310C149923435 @default.
- W2011393310 hasConceptScore W2011393310C150966472 @default.
- W2011393310 hasConceptScore W2011393310C188816634 @default.
- W2011393310 hasConceptScore W2011393310C201903717 @default.
- W2011393310 hasConceptScore W2011393310C2780221984 @default.
- W2011393310 hasConceptScore W2011393310C2780613262 @default.
- W2011393310 hasConceptScore W2011393310C2908647359 @default.
- W2011393310 hasConceptScore W2011393310C511355011 @default.
- W2011393310 hasConceptScore W2011393310C61470247 @default.
- W2011393310 hasConceptScore W2011393310C71924100 @default.
- W2011393310 hasConceptScore W2011393310C72563966 @default.
- W2011393310 hasConceptScore W2011393310C99454951 @default.
- W2011393310 hasIssue "3" @default.
- W2011393310 hasLocation W20113933101 @default.
- W2011393310 hasLocation W20113933102 @default.
- W2011393310 hasOpenAccess W2011393310 @default.
- W2011393310 hasPrimaryLocation W20113933101 @default.
- W2011393310 hasRelatedWork W2013490181 @default.
- W2011393310 hasRelatedWork W2050001240 @default.