FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011402079> ?p ?o ?g. }

• W2011402079 endingPage "626" @default.
• W2011402079 startingPage "617" @default.
• W2011402079 abstract "Hepatitis B virus (HBV)-specific cytotoxic T lymphocytes (CTLs) can abolish HBV gene expression and replication through a noncytopathic mechanism mediated by tumor necrosis factor-α (TNF-α). However, the molecular mechanisms of TNF-α antiviral activity are not completely understood. To examine TNF-α-induced cellular responses and identify genes involved in anti-HBV activity, cDNA microarrays dotted with 14, 112 human genes were used to examine the transcriptional changes in HepG2 after treatment with TNF-α for 6 h. The results showed that many genes related to ligands and receptors, signal transduction including the TNF-α signaling pathway, mitochondrial and ribosomal proteins, and transcription regulation were induced by TNF-α. Interestingly, the TNF-α-inducible gene cIAP2 was found to inhibit HBV protein synthesis, viral replication, and transcription. Taken together, our results revealed the global effects of TNF-α treatment on hepatocellular gene expression. The antiviral genes identified by microarray could be developed as potential new anti-HBV drugs or for other novel therapies." @default.
• W2011402079 created "2016-06-24" @default.
• W2011402079 creator A5010804247 @default.
• W2011402079 creator A5013626210 @default.
• W2011402079 creator A5021150777 @default.
• W2011402079 creator A5031528894 @default.
• W2011402079 creator A5036408326 @default.
• W2011402079 creator A5042519138 @default.
• W2011402079 creator A5071232392 @default.
• W2011402079 creator A5071233167 @default.
• W2011402079 creator A5077212820 @default.
• W2011402079 date "2005-10-01" @default.
• W2011402079 modified "2023-09-24" @default.
• W2011402079 title "Cellular cIAP2Gene Expression Associated with Anti-HBV Activity of TNF-α in Hepatoblastoma Cells" @default.
• W2011402079 cites W1806270851 @default.
• W2011402079 cites W1972429613 @default.
• W2011402079 cites W1972987115 @default.
• W2011402079 cites W1985407539 @default.
• W2011402079 cites W1990683719 @default.
• W2011402079 cites W1996464993 @default.
• W2011402079 cites W2004038084 @default.
• W2011402079 cites W2008211081 @default.
• W2011402079 cites W2010552845 @default.
• W2011402079 cites W2016909880 @default.
• W2011402079 cites W2022376508 @default.
• W2011402079 cites W2030958510 @default.
• W2011402079 cites W2043141000 @default.
• W2011402079 cites W2045261504 @default.
• W2011402079 cites W2073108299 @default.
• W2011402079 cites W2105546213 @default.
• W2011402079 cites W2106931436 @default.
• W2011402079 cites W2127121239 @default.
• W2011402079 cites W2129889907 @default.
• W2011402079 cites W2131188831 @default.
• W2011402079 cites W2132728901 @default.
• W2011402079 cites W2136761089 @default.
• W2011402079 cites W2140206005 @default.
• W2011402079 cites W2154760977 @default.
• W2011402079 cites W2157098396 @default.
• W2011402079 cites W2159633595 @default.
• W2011402079 cites W2166504564 @default.
• W2011402079 cites W4238948186 @default.
• W2011402079 doi "https://doi.org/10.1089/jir.2005.25.617" @default.
• W2011402079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16241860" @default.
• W2011402079 hasPublicationYear "2005" @default.
• W2011402079 type Work @default.
• W2011402079 sameAs 2011402079 @default.
• W2011402079 citedByCount "3" @default.
• W2011402079 countsByYear W20114020792019 @default.
• W2011402079 crossrefType "journal-article" @default.
• W2011402079 hasAuthorship W2011402079A5010804247 @default.
• W2011402079 hasAuthorship W2011402079A5013626210 @default.
• W2011402079 hasAuthorship W2011402079A5021150777 @default.
• W2011402079 hasAuthorship W2011402079A5031528894 @default.
• W2011402079 hasAuthorship W2011402079A5036408326 @default.
• W2011402079 hasAuthorship W2011402079A5042519138 @default.
• W2011402079 hasAuthorship W2011402079A5071232392 @default.
• W2011402079 hasAuthorship W2011402079A5071233167 @default.
• W2011402079 hasAuthorship W2011402079A5077212820 @default.
• W2011402079 hasConcept C104317684 @default.
• W2011402079 hasConcept C126838900 @default.
• W2011402079 hasConcept C138885662 @default.
• W2011402079 hasConcept C140704245 @default.
• W2011402079 hasConcept C150194340 @default.
• W2011402079 hasConcept C153911025 @default.
• W2011402079 hasConcept C154317977 @default.
• W2011402079 hasConcept C159047783 @default.
• W2011402079 hasConcept C17991360 @default.
• W2011402079 hasConcept C179926584 @default.
• W2011402079 hasConcept C186836561 @default.
• W2011402079 hasConcept C202751555 @default.
• W2011402079 hasConcept C203014093 @default.
• W2011402079 hasConcept C2522874641 @default.
• W2011402079 hasConcept C2776304256 @default.
• W2011402079 hasConcept C2780593183 @default.
• W2011402079 hasConcept C41895202 @default.
• W2011402079 hasConcept C54355233 @default.
• W2011402079 hasConcept C71924100 @default.
• W2011402079 hasConcept C86803240 @default.
• W2011402079 hasConceptScore W2011402079C104317684 @default.
• W2011402079 hasConceptScore W2011402079C126838900 @default.
• W2011402079 hasConceptScore W2011402079C138885662 @default.
• W2011402079 hasConceptScore W2011402079C140704245 @default.
• W2011402079 hasConceptScore W2011402079C150194340 @default.
• W2011402079 hasConceptScore W2011402079C153911025 @default.
• W2011402079 hasConceptScore W2011402079C154317977 @default.
• W2011402079 hasConceptScore W2011402079C159047783 @default.
• W2011402079 hasConceptScore W2011402079C17991360 @default.
• W2011402079 hasConceptScore W2011402079C179926584 @default.
• W2011402079 hasConceptScore W2011402079C186836561 @default.
• W2011402079 hasConceptScore W2011402079C202751555 @default.
• W2011402079 hasConceptScore W2011402079C203014093 @default.
• W2011402079 hasConceptScore W2011402079C2522874641 @default.
• W2011402079 hasConceptScore W2011402079C2776304256 @default.
• W2011402079 hasConceptScore W2011402079C2780593183 @default.
• W2011402079 hasConceptScore W2011402079C41895202 @default.
• W2011402079 hasConceptScore W2011402079C54355233 @default.
• W2011402079 hasConceptScore W2011402079C71924100 @default.

• next