Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011464031> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2011464031 endingPage "1254" @default.
- W2011464031 startingPage "1249" @default.
- W2011464031 abstract "The interaction of radiation and Adriamycin (ADR) in vivo was studied in 3 different sizes of the EMT6/SF tumor, i.e., 1 cm flank tumors, 2 mm macroscopic lung nodules, and microscopic pulmonary metastases. For the flank tumors the drug was slightly more effective when administered intravenously (IV) than intraperitoneally when survival was assayed in vitro at 24 hours after drug treatment. No significant cell kill or growth delay was observed at doses below 15 mg/kg when the response was assayed with the lung colony assay and regrowth analysis. When ADR was combined with radiation, there was no significant difference in survival with variation of the time interval between drug and radiation administration from −48 hrs. to +48 hrs. When flank tumors were treated with ADR, 15 mg/kg IV, followed in 24 firs. by graded doses of radiation, additive killing effect was seen at low radiation doses but the survival levels were the same as radiation alone at high doses. Adriamycin was slightly more effective against 2 mm artificial macroscopic pulmonary metastases than the flank tumors, but it did not cause significant changes in the radiation dose response curve of these tumors. When the EMT6/SF tumor cells were treated in the lungs 24 hours after transplantation, there was increased cell kill with ADR alone when compared to the 2 mm macroscopic metastases and 1 cm flank tumors. The combined effects of ADR and radiation for the microscopic pulmonary metastases appeared to be strictly additive killing." @default.
- W2011464031 created "2016-06-24" @default.
- W2011464031 creator A5056041583 @default.
- W2011464031 creator A5073984522 @default.
- W2011464031 creator A5079816161 @default.
- W2011464031 creator A5089737672 @default.
- W2011464031 date "1979-08-01" @default.
- W2011464031 modified "2023-10-18" @default.
- W2011464031 title "Interaction of radiation and adriamycin on the EMT6 tumor as a function of tumor size and assay method" @default.
- W2011464031 cites W1522702175 @default.
- W2011464031 cites W1523440827 @default.
- W2011464031 cites W1849539815 @default.
- W2011464031 cites W1968040987 @default.
- W2011464031 cites W1974048463 @default.
- W2011464031 cites W1987179417 @default.
- W2011464031 cites W1988691204 @default.
- W2011464031 cites W2000272679 @default.
- W2011464031 cites W2020893327 @default.
- W2011464031 cites W2023435651 @default.
- W2011464031 cites W2027773551 @default.
- W2011464031 cites W2052073962 @default.
- W2011464031 cites W2067720747 @default.
- W2011464031 cites W2071029954 @default.
- W2011464031 cites W2092949118 @default.
- W2011464031 cites W2127991375 @default.
- W2011464031 cites W2144536651 @default.
- W2011464031 cites W2413802825 @default.
- W2011464031 doi "https://doi.org/10.1016/0360-3016(79)90648-5" @default.
- W2011464031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/528272" @default.
- W2011464031 hasPublicationYear "1979" @default.
- W2011464031 type Work @default.
- W2011464031 sameAs 2011464031 @default.
- W2011464031 citedByCount "23" @default.
- W2011464031 crossrefType "journal-article" @default.
- W2011464031 hasAuthorship W2011464031A5056041583 @default.
- W2011464031 hasAuthorship W2011464031A5073984522 @default.
- W2011464031 hasAuthorship W2011464031A5079816161 @default.
- W2011464031 hasAuthorship W2011464031A5089737672 @default.
- W2011464031 hasConcept C105702510 @default.
- W2011464031 hasConcept C126322002 @default.
- W2011464031 hasConcept C142724271 @default.
- W2011464031 hasConcept C150903083 @default.
- W2011464031 hasConcept C207001950 @default.
- W2011464031 hasConcept C2777714996 @default.
- W2011464031 hasConcept C2780395675 @default.
- W2011464031 hasConcept C2911091166 @default.
- W2011464031 hasConcept C2989005 @default.
- W2011464031 hasConcept C509974204 @default.
- W2011464031 hasConcept C71924100 @default.
- W2011464031 hasConcept C86803240 @default.
- W2011464031 hasConceptScore W2011464031C105702510 @default.
- W2011464031 hasConceptScore W2011464031C126322002 @default.
- W2011464031 hasConceptScore W2011464031C142724271 @default.
- W2011464031 hasConceptScore W2011464031C150903083 @default.
- W2011464031 hasConceptScore W2011464031C207001950 @default.
- W2011464031 hasConceptScore W2011464031C2777714996 @default.
- W2011464031 hasConceptScore W2011464031C2780395675 @default.
- W2011464031 hasConceptScore W2011464031C2911091166 @default.
- W2011464031 hasConceptScore W2011464031C2989005 @default.
- W2011464031 hasConceptScore W2011464031C509974204 @default.
- W2011464031 hasConceptScore W2011464031C71924100 @default.
- W2011464031 hasConceptScore W2011464031C86803240 @default.
- W2011464031 hasIssue "8" @default.
- W2011464031 hasLocation W20114640311 @default.
- W2011464031 hasLocation W20114640312 @default.
- W2011464031 hasOpenAccess W2011464031 @default.
- W2011464031 hasPrimaryLocation W20114640311 @default.
- W2011464031 hasRelatedWork W2021771973 @default.
- W2011464031 hasRelatedWork W2022944059 @default.
- W2011464031 hasRelatedWork W2048191766 @default.
- W2011464031 hasRelatedWork W2168923614 @default.
- W2011464031 hasRelatedWork W2384708512 @default.
- W2011464031 hasRelatedWork W2420746378 @default.
- W2011464031 hasRelatedWork W2428341374 @default.
- W2011464031 hasRelatedWork W2746064660 @default.
- W2011464031 hasRelatedWork W3005652238 @default.
- W2011464031 hasRelatedWork W4253632170 @default.
- W2011464031 hasVolume "5" @default.
- W2011464031 isParatext "false" @default.
- W2011464031 isRetracted "false" @default.
- W2011464031 magId "2011464031" @default.
- W2011464031 workType "article" @default.