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- W2011472703 abstract "Induction of the viral BZLF1 gene has previously been shown to be one of the first steps in the reactivation of Epstein-Barr virus (EBV). Using an EBV oriP episomal vector system, we have reconstituted the regulation of the promoter for BZLF1 on stably transfected episomes, mapped promoter elements required for that regulation, and investigated mechanisms that may control the switch between latency and the lytic cycle. Changes in histone acetylation at the promoter for the BZLF1 gene appear to be a key part of the reactivation mechanism of this herpesvirus." @default.
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- W2011472703 date "2000-01-15" @default.
- W2011472703 modified "2023-09-27" @default.
- W2011472703 title "Histone Acetylation and Reactivation of Epstein-Barr Virus from Latency" @default.
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- W2011472703 doi "https://doi.org/10.1128/jvi.74.2.710-720.2000" @default.
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