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• W2011473924 abstract "A peculiar non-hypertrophic myocardiopathy is described which occurred in three and possibly five generations of a single family. Clinical features included systolic murmurs, electrocardiographic abnormalities, and sudden cardiac death with a paucity of symptoms of cardiac dysfunction. Pathological studies in three generations showed a striking similarity of cardiac findings including globular and dilated ventricles, endocardial fibroelastosis, and mitral valve thickening. Myocardium in two showed basophilic degeneration and fibrosis. A retrospective genealogic analysis and a prospective clinical evaluation of living family members suggested an autosomal dominant mode of inheritance with variable penetrance. The cause of this heritable myocardiopathy is presumably a mutant gene; the biochemical defect to which the mutant gene gives rise remains unknown." @default.
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• W2011473924 date "1978-08-01" @default.
• W2011473924 modified "2023-10-17" @default.
• W2011473924 title "Idiopathic familial myocardiopathy in three generations: A clinical and pathologic study" @default.
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• W2011473924 doi "https://doi.org/10.1016/0002-8703(78)90082-0" @default.
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