FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011495279> ?p ?o ?g. }

• W2011495279 endingPage "12" @default.
• W2011495279 startingPage "1" @default.
• W2011495279 abstract "Dantrolene was reported to suppress ventricular fibrillation (VF) in failing hearts with acute myocardial infarction, but its antiarrhythmic efficacy in regional ischemia-reperfusion (IR) hearts remains debatable. Heart failure (HF) was induced by right ventricular pacing. The IR rabbit model was created by coronary artery ligation for 30 min, followed by reperfusion for 15 min in vivo in both HF and non-HF groups ( n = 9 in each group). Simultaneous voltage and intracellular Ca 2+ (Ca i ) optical mapping was then performed in isolated Langendorff-perfused hearts. Electrophysiological studies were conducted and VF inducibility was evaluated by dynamic pacing. Dantrolene (10 μ M) was administered after baseline studies. The HF group had a higher VF inducibility than the control group. Dantrolene had both antiarrhythmic (prolonged action potential duration (APD) and effective refractory period) and proarrhythmic effects (slowed conduction velocity, steepened APD restitution slope, and enhanced arrhythmogenic alternans induction) but had no significant effects on ventricular premature beat (VPB) suppression and VF inducibility in both groups. A higher VF conversion rate in the non-HF group was likely due to greater APD prolonging effects in smaller hearts compared to the HF group. The lack of significant effects on VPB suppression by dantrolene suggests that triggered activity might not be the dominant mechanism responsible for VPB induction in the IR model." @default.
• W2011495279 created "2016-06-24" @default.
• W2011495279 creator A5010050673 @default.
• W2011495279 creator A5015614663 @default.
• W2011495279 creator A5016298087 @default.
• W2011495279 creator A5029271999 @default.
• W2011495279 creator A5036251543 @default.
• W2011495279 creator A5054621713 @default.
• W2011495279 date "2015-01-01" @default.
• W2011495279 modified "2023-10-02" @default.
• W2011495279 title "Effects of Dantrolene on Arrhythmogenicity in Isolated Regional Ischemia-Reperfusion Rabbit Hearts with or without Pacing-Induced Heart Failure" @default.
• W2011495279 cites W1520768735 @default.
• W2011495279 cites W159433272 @default.
• W2011495279 cites W1829402653 @default.
• W2011495279 cites W1966781482 @default.
• W2011495279 cites W1984658117 @default.
• W2011495279 cites W1985478524 @default.
• W2011495279 cites W1993137287 @default.
• W2011495279 cites W1997768837 @default.
• W2011495279 cites W1999675270 @default.
• W2011495279 cites W2014140660 @default.
• W2011495279 cites W2030858573 @default.
• W2011495279 cites W2037260153 @default.
• W2011495279 cites W2048652590 @default.
• W2011495279 cites W2049858915 @default.
• W2011495279 cites W2065116293 @default.
• W2011495279 cites W2068560328 @default.
• W2011495279 cites W2073026156 @default.
• W2011495279 cites W2076910520 @default.
• W2011495279 cites W2088020365 @default.
• W2011495279 cites W2089264497 @default.
• W2011495279 cites W2117176106 @default.
• W2011495279 cites W2119277805 @default.
• W2011495279 cites W2119588279 @default.
• W2011495279 cites W2133963004 @default.
• W2011495279 cites W2149461833 @default.
• W2011495279 cites W2155421107 @default.
• W2011495279 cites W2155596109 @default.
• W2011495279 cites W2166375411 @default.
• W2011495279 cites W2170903404 @default.
• W2011495279 cites W2183014949 @default.
• W2011495279 cites W228800717 @default.
• W2011495279 cites W237870959 @default.
• W2011495279 cites W2402328395 @default.
• W2011495279 doi "https://doi.org/10.1155/2015/532820" @default.
• W2011495279 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4350948" @default.
• W2011495279 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25789321" @default.
• W2011495279 hasPublicationYear "2015" @default.
• W2011495279 type Work @default.
• W2011495279 sameAs 2011495279 @default.
• W2011495279 citedByCount "4" @default.
• W2011495279 countsByYear W20114952792018 @default.
• W2011495279 countsByYear W20114952792020 @default.
• W2011495279 countsByYear W20114952792023 @default.
• W2011495279 crossrefType "journal-article" @default.
• W2011495279 hasAuthorship W2011495279A5010050673 @default.
• W2011495279 hasAuthorship W2011495279A5015614663 @default.
• W2011495279 hasAuthorship W2011495279A5016298087 @default.
• W2011495279 hasAuthorship W2011495279A5029271999 @default.
• W2011495279 hasAuthorship W2011495279A5036251543 @default.
• W2011495279 hasAuthorship W2011495279A5054621713 @default.
• W2011495279 hasBestOaLocation W20114952791 @default.
• W2011495279 hasConcept C126322002 @default.
• W2011495279 hasConcept C164705383 @default.
• W2011495279 hasConcept C185263204 @default.
• W2011495279 hasConcept C189327125 @default.
• W2011495279 hasConcept C2778198053 @default.
• W2011495279 hasConcept C2781005686 @default.
• W2011495279 hasConcept C2781460320 @default.
• W2011495279 hasConcept C28289500 @default.
• W2011495279 hasConcept C42219234 @default.
• W2011495279 hasConcept C519063684 @default.
• W2011495279 hasConcept C541997718 @default.
• W2011495279 hasConcept C71924100 @default.
• W2011495279 hasConceptScore W2011495279C126322002 @default.
• W2011495279 hasConceptScore W2011495279C164705383 @default.
• W2011495279 hasConceptScore W2011495279C185263204 @default.
• W2011495279 hasConceptScore W2011495279C189327125 @default.
• W2011495279 hasConceptScore W2011495279C2778198053 @default.
• W2011495279 hasConceptScore W2011495279C2781005686 @default.
• W2011495279 hasConceptScore W2011495279C2781460320 @default.
• W2011495279 hasConceptScore W2011495279C28289500 @default.
• W2011495279 hasConceptScore W2011495279C42219234 @default.
• W2011495279 hasConceptScore W2011495279C519063684 @default.
• W2011495279 hasConceptScore W2011495279C541997718 @default.
• W2011495279 hasConceptScore W2011495279C71924100 @default.
• W2011495279 hasLocation W20114952791 @default.
• W2011495279 hasLocation W20114952792 @default.
• W2011495279 hasLocation W20114952793 @default.
• W2011495279 hasLocation W20114952794 @default.
• W2011495279 hasLocation W20114952795 @default.
• W2011495279 hasOpenAccess W2011495279 @default.
• W2011495279 hasPrimaryLocation W20114952791 @default.
• W2011495279 hasRelatedWork W1568088667 @default.
• W2011495279 hasRelatedWork W2011495279 @default.
• W2011495279 hasRelatedWork W2051199387 @default.
• W2011495279 hasRelatedWork W2071521299 @default.
• W2011495279 hasRelatedWork W2082743754 @default.

• next