Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011509970> ?p ?o ?g. }
- W2011509970 endingPage "151" @default.
- W2011509970 startingPage "143" @default.
- W2011509970 abstract "Enrichment of low density lipoprotein (LDL) with long-chain fatty acids, such as eicosapentaenoic acid (EPA; 20:5 n-3) and docosahexaenoic acid (DHA; 22:6 n-3) found in fish oil, is thought to increase its oxidative susceptibility although such an increase has not been clearly demonstrated. The purpose of this study was to determine the composition and fatty acid concentration of LDL obtained from postmenopausal women given a supplement of fish oil and relate these values to its oxidative susceptibility. Fish oil supplementation significantly increased LDL concentration of EPA (P = 0.0001) and DHA (P = 0.0001) and decreased that of linoleic acid P = 0.006). The concentration of free cholesterol, cholesterol ester, phospholipids and protein was unchanged while triglyceride concentration increased 8% (P = 0.02). Cu2+-mediated oxidation resulted in a shorter lag time, slower oxidation rate and similar concentrations of conjugated dienes of EPA/DHA-enriched LDL than EPA/DHA-unenriched LDL. Stepwise multiple regression indicated that the primary predictor of oxidative susceptibility of LDL was linoleic acid, even after enrichment with EPA and DHA. The oxidation rate of EPA/DHA-unenriched LDL correlated with the cholesteryl ester concentration (P = 0.003) while that of EPA/DHA-enriched correlated with the concentration of phospholipids (P = 0.03). These data suggest that EPA/DHA-enriched LDL have decreased oxidative susceptibility and that surface lipids may mediate its rate of oxidation." @default.
- W2011509970 created "2016-06-24" @default.
- W2011509970 creator A5008811509 @default.
- W2011509970 creator A5016536177 @default.
- W2011509970 creator A5026130611 @default.
- W2011509970 date "1998-08-01" @default.
- W2011509970 modified "2023-10-16" @default.
- W2011509970 title "Influence of long-chain polyunsaturated fatty acids on oxidation of low density lipoprotein" @default.
- W2011509970 cites W1536008717 @default.
- W2011509970 cites W1775749144 @default.
- W2011509970 cites W1822877682 @default.
- W2011509970 cites W1886616685 @default.
- W2011509970 cites W1890797122 @default.
- W2011509970 cites W1892253401 @default.
- W2011509970 cites W1925530450 @default.
- W2011509970 cites W1938228961 @default.
- W2011509970 cites W1946263363 @default.
- W2011509970 cites W1967765835 @default.
- W2011509970 cites W1970705834 @default.
- W2011509970 cites W1987657041 @default.
- W2011509970 cites W1997745709 @default.
- W2011509970 cites W2010948272 @default.
- W2011509970 cites W2028695216 @default.
- W2011509970 cites W2030971565 @default.
- W2011509970 cites W2032508526 @default.
- W2011509970 cites W2049267063 @default.
- W2011509970 cites W2049432724 @default.
- W2011509970 cites W2050215832 @default.
- W2011509970 cites W2051121049 @default.
- W2011509970 cites W2055074148 @default.
- W2011509970 cites W2055111376 @default.
- W2011509970 cites W2055457129 @default.
- W2011509970 cites W2057726272 @default.
- W2011509970 cites W2064487219 @default.
- W2011509970 cites W2066100276 @default.
- W2011509970 cites W2088550457 @default.
- W2011509970 cites W2099903211 @default.
- W2011509970 cites W2104573407 @default.
- W2011509970 cites W2159506419 @default.
- W2011509970 cites W2159689725 @default.
- W2011509970 cites W2161188230 @default.
- W2011509970 cites W2161201457 @default.
- W2011509970 cites W2212323528 @default.
- W2011509970 cites W2291149304 @default.
- W2011509970 cites W2325815717 @default.
- W2011509970 doi "https://doi.org/10.1016/s0952-3278(98)90093-x" @default.
- W2011509970 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9774178" @default.
- W2011509970 hasPublicationYear "1998" @default.
- W2011509970 type Work @default.
- W2011509970 sameAs 2011509970 @default.
- W2011509970 citedByCount "29" @default.
- W2011509970 countsByYear W20115099702013 @default.
- W2011509970 countsByYear W20115099702014 @default.
- W2011509970 countsByYear W20115099702020 @default.
- W2011509970 crossrefType "journal-article" @default.
- W2011509970 hasAuthorship W2011509970A5008811509 @default.
- W2011509970 hasAuthorship W2011509970A5016536177 @default.
- W2011509970 hasAuthorship W2011509970A5026130611 @default.
- W2011509970 hasConcept C126322002 @default.
- W2011509970 hasConcept C134018914 @default.
- W2011509970 hasConcept C185592680 @default.
- W2011509970 hasConcept C19038510 @default.
- W2011509970 hasConcept C2776091944 @default.
- W2011509970 hasConcept C2776448209 @default.
- W2011509970 hasConcept C2777171753 @default.
- W2011509970 hasConcept C2778163477 @default.
- W2011509970 hasConcept C2778913445 @default.
- W2011509970 hasConcept C2779620165 @default.
- W2011509970 hasConcept C2779780233 @default.
- W2011509970 hasConcept C2779946292 @default.
- W2011509970 hasConcept C2780072125 @default.
- W2011509970 hasConcept C2780809830 @default.
- W2011509970 hasConcept C2909208804 @default.
- W2011509970 hasConcept C31903555 @default.
- W2011509970 hasConcept C505870484 @default.
- W2011509970 hasConcept C543025807 @default.
- W2011509970 hasConcept C55493867 @default.
- W2011509970 hasConcept C57600042 @default.
- W2011509970 hasConcept C71924100 @default.
- W2011509970 hasConcept C86803240 @default.
- W2011509970 hasConceptScore W2011509970C126322002 @default.
- W2011509970 hasConceptScore W2011509970C134018914 @default.
- W2011509970 hasConceptScore W2011509970C185592680 @default.
- W2011509970 hasConceptScore W2011509970C19038510 @default.
- W2011509970 hasConceptScore W2011509970C2776091944 @default.
- W2011509970 hasConceptScore W2011509970C2776448209 @default.
- W2011509970 hasConceptScore W2011509970C2777171753 @default.
- W2011509970 hasConceptScore W2011509970C2778163477 @default.
- W2011509970 hasConceptScore W2011509970C2778913445 @default.
- W2011509970 hasConceptScore W2011509970C2779620165 @default.
- W2011509970 hasConceptScore W2011509970C2779780233 @default.
- W2011509970 hasConceptScore W2011509970C2779946292 @default.
- W2011509970 hasConceptScore W2011509970C2780072125 @default.
- W2011509970 hasConceptScore W2011509970C2780809830 @default.
- W2011509970 hasConceptScore W2011509970C2909208804 @default.
- W2011509970 hasConceptScore W2011509970C31903555 @default.
- W2011509970 hasConceptScore W2011509970C505870484 @default.
- W2011509970 hasConceptScore W2011509970C543025807 @default.