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- W2011528372 abstract "demonstrated that loco-regional control was associated with decreasing stage (HR 5.6, 95% CI 1.9-16.3, p50.002, for stage III-IVA vs. 0-2) and higher total dose (HR 1.1, 95% CI 1.1-1.2, p50.015). Chemotherapy use and tumor size were associated with improved outcomes on univariate analysis. Crude rates of late toxicity $ grade 3 were: GYN 6.5%, GI 5.5%, and GU 4.6%. Conclusions: This series demonstrates excellent long-term outcomes in primary vaginal cancer patients receiving HDR brachytherapy based treatment. 5-year loco-regional control was 79.5% with higher total dose and lower stage most strongly associated with improved control. Grade 3þ toxicity rates were low at around 5%. We believe that the high locoregional control rates seen in patients including those with advanced disease reflects the high dose that can be safely delivered to the tumor volume with interstitial HDR brachytherapy." @default.
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- W2011528372 date "2014-03-01" @default.
- W2011528372 modified "2023-10-02" @default.
- W2011528372 title "Extended Clinical Outcomes of 3D High-Dose-Rate Intracavitary Brachytherapy with MRI-Based Planning for Treatment of Cervical Cancer" @default.
- W2011528372 doi "https://doi.org/10.1016/j.brachy.2014.02.247" @default.
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