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- W2011544460 abstract "We compared the ability of a small radiation detector probe and a gamma camera to detect tumors in a phantom system. We used a collimated NaI probe of 0.8 cm2 area and a Picker 4/15/37 camera. Three 1 cm3 simulated tumors were placed in a 301 tank containing 2 nCi/ml Co-57; tumor activity was 20, 80 and 200 nCi. The camera was positioned with a Tc dynamic collimator in contact with the tank, and 2 min computer images of all 3 tumors were obtained with the tumor at 0, 5, 10 and 15 cm from the tank wall. A region of interest was drawn around each tumor and a background area, and successive images were formed by raising the lower image threshold in 5% increments. Both smoothed and unsmoothed images were evaluated. The true positive and false positive fractions were calculated for each threshold, and a maximum likelihood fit was made for the receiver operating characteristic (ROC) curve. The area under the ROC curve was the figure of merit used; d' values were also calculated. Probe counts were obtained in the tank for 15 sec for each tumor at separations of 0, 1, 2 and 5 cm. Probe data were also subjected to threshold variations to generate ROC curves. Camera performance degraded rapidly with depth of tumors, and was independent of image smoothing. Probe performance was sensitive to separation from tumors, but relatively insensitive to the volume of background activity in the field of view. Probe performance was superior to camera performance for all conditions when the probe to tumor separation was less than 2 cm. We conclude that probes are superior to gamma cameras for detecting small tumors, provided the probe can be positioned close to the tumors, such as during surgery or endoscopy." @default.
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- W2011544460 date "1984-09-01" @default.
- W2011544460 modified "2023-09-28" @default.
- W2011544460 title "COMPARISON OF A SMALL PROBE AND A GAMMA CAMERA FOR TUMOR DETECTION" @default.
- W2011544460 doi "https://doi.org/10.1097/00003072-198409001-00008" @default.
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