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- W2011562062 abstract "Meeting Abstracts1 May 1971Multiple Myeloma—Intermittent, Combination Chemotherapy Compared with Low-Dose Continuous Alkylator Therapy.Ralph P. George Jr., M.D., James L. Poth, M.D., David Gordon, M.D., Stanley L. Schrier, M.D.Ralph P. George Jr., M.D.Search for more papers by this author, James L. Poth, M.D.Search for more papers by this author, David Gordon, M.D.Search for more papers by this author, Stanley L. Schrier, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-74-5-836_5 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptControversy exists regarding the efficacy of various treatment schedules and drug combinations for patients with multiple myeloma. This study compared results of long-term, continuous alkylator therapy with those of intermittent, high-dose pulse therapy using melphalan and prednisone in combination. During the past 2 years 31 patients with multiple myeloma were treated with high-dose, combination pulse therapy using melphalan, 0.25 mg/kg body weight/day, and prednisone, 2.0 mg/kg body weight/day. Both drugs were given orally for 4 days at 6-week intervals. The results were compared with previous experience at the Stanford University Hospital using continuous, low-dose alkylator therapy in 22 patients with... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Stanford, Calif. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1971Volume 74, Issue 5Page: 836-837KeywordsCombination chemotherapyDrugsHeart rateMultiple myeloma Issue Published: 1 May 1971 PDF DownloadLoading ..." @default.
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- W2011562062 title "Multiple Myeloma—Intermittent, Combination Chemotherapy Compared with Low-Dose Continuous Alkylator Therapy." @default.
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