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• W2011564579 abstract "We have previously shown that IKKs are aberrantly activated in colon cancer cells leading to SMRT phosphorylation and its release from the chromatin. We now show that IKKalpha phosphorylates the homologous N-CoR corepressor in serines 2345 and 2348 creating a functional 14-3-3 binding domain (RK(p)S(2348)KSP). Moreover, we have analyzed the subcellular localization of N-CoR in 43 colorectal cancer samples and we have found that aberrant cytoplasmic distribution of N-CoR is a general trait of these tumors." @default.
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• W2011564579 date "2007-07-15" @default.
• W2011564579 modified "2023-10-17" @default.
• W2011564579 title "Aberrant Cytoplasmic Localization of N-CoR in Colorectal Tumors" @default.
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• W2011564579 doi "https://doi.org/10.4161/cc.6.14.4429" @default.
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