FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011611726> ?p ?o ?g. }

• W2011611726 endingPage "965" @default.
• W2011611726 startingPage "957" @default.
• W2011611726 abstract "Vertebrate centrioles lose their geometric scaffold, the cartwheel, during mitosis, concurrently with gaining the ability to recruit the pericentriolar material (PCM) and thereby function as the centrosome. Cartwheel removal has recently been implicated in centriole duplication, but whether “cartwheel-less” centrioles are intrinsically stable or must be maintained through other modifications remains unclear. Here, we identify a newborn centriole-enriched protein, KIAA1731/CEP295, specifically mediating centriole-to-centrosome conversion but dispensable for cartwheel removal. In the absence of CEP295, centrioles form in the S/G2 phase and lose their associated cartwheel in mitosis but cannot be converted to centrosomes, uncoupling the two events. Strikingly, centrioles devoid of both the PCM and the cartwheel progressively lose centriolar components, whereas centrioles associating with either the cartwheel or PCM alone can exist stably. Thus, cartwheel removal can have grave repercussions to centriole stability, and centriole-to-centrosome conversion mediated by CEP295 must occur in parallel to maintain cartwheel-less centrioles for duplication." @default.
• W2011611726 created "2016-06-24" @default.
• W2011611726 creator A5002979482 @default.
• W2011611726 creator A5015641908 @default.
• W2011611726 creator A5077227628 @default.
• W2011611726 creator A5081678565 @default.
• W2011611726 date "2014-08-01" @default.
• W2011611726 modified "2023-09-30" @default.
• W2011611726 title "Stabilization of Cartwheel-less Centrioles for Duplication Requires CEP295-Mediated Centriole-to-Centrosome Conversion" @default.
• W2011611726 cites W1947936721 @default.
• W2011611726 cites W1988941690 @default.
• W2011611726 cites W2003171404 @default.
• W2011611726 cites W2004165748 @default.
• W2011611726 cites W2019013949 @default.
• W2011611726 cites W2035895891 @default.
• W2011611726 cites W2040825881 @default.
• W2011611726 cites W2042298827 @default.
• W2011611726 cites W2049460100 @default.
• W2011611726 cites W2058537133 @default.
• W2011611726 cites W2071544384 @default.
• W2011611726 cites W2072567708 @default.
• W2011611726 cites W2078873544 @default.
• W2011611726 cites W2086857229 @default.
• W2011611726 cites W2110042532 @default.
• W2011611726 cites W2110337318 @default.
• W2011611726 cites W2111005916 @default.
• W2011611726 cites W2128508997 @default.
• W2011611726 cites W2143259378 @default.
• W2011611726 cites W2144833749 @default.
• W2011611726 cites W2152864434 @default.
• W2011611726 cites W2153441154 @default.
• W2011611726 cites W2160708012 @default.
• W2011611726 doi "https://doi.org/10.1016/j.celrep.2014.07.022" @default.
• W2011611726 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4152953" @default.
• W2011611726 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25131205" @default.
• W2011611726 hasPublicationYear "2014" @default.
• W2011611726 type Work @default.
• W2011611726 sameAs 2011611726 @default.
• W2011611726 citedByCount "87" @default.
• W2011611726 countsByYear W20116117262015 @default.
• W2011611726 countsByYear W20116117262016 @default.
• W2011611726 countsByYear W20116117262017 @default.
• W2011611726 countsByYear W20116117262018 @default.
• W2011611726 countsByYear W20116117262019 @default.
• W2011611726 countsByYear W20116117262020 @default.
• W2011611726 countsByYear W20116117262021 @default.
• W2011611726 countsByYear W20116117262022 @default.
• W2011611726 countsByYear W20116117262023 @default.
• W2011611726 crossrefType "journal-article" @default.
• W2011611726 hasAuthorship W2011611726A5002979482 @default.
• W2011611726 hasAuthorship W2011611726A5015641908 @default.
• W2011611726 hasAuthorship W2011611726A5077227628 @default.
• W2011611726 hasAuthorship W2011611726A5081678565 @default.
• W2011611726 hasBestOaLocation W20116117261 @default.
• W2011611726 hasConcept C104317684 @default.
• W2011611726 hasConcept C10447061 @default.
• W2011611726 hasConcept C115811362 @default.
• W2011611726 hasConcept C131151476 @default.
• W2011611726 hasConcept C1491633281 @default.
• W2011611726 hasConcept C20418707 @default.
• W2011611726 hasConcept C29537977 @default.
• W2011611726 hasConcept C44064316 @default.
• W2011611726 hasConcept C48342290 @default.
• W2011611726 hasConcept C54355233 @default.
• W2011611726 hasConcept C86803240 @default.
• W2011611726 hasConcept C93304396 @default.
• W2011611726 hasConcept C95444343 @default.
• W2011611726 hasConceptScore W2011611726C104317684 @default.
• W2011611726 hasConceptScore W2011611726C10447061 @default.
• W2011611726 hasConceptScore W2011611726C115811362 @default.
• W2011611726 hasConceptScore W2011611726C131151476 @default.
• W2011611726 hasConceptScore W2011611726C1491633281 @default.
• W2011611726 hasConceptScore W2011611726C20418707 @default.
• W2011611726 hasConceptScore W2011611726C29537977 @default.
• W2011611726 hasConceptScore W2011611726C44064316 @default.
• W2011611726 hasConceptScore W2011611726C48342290 @default.
• W2011611726 hasConceptScore W2011611726C54355233 @default.
• W2011611726 hasConceptScore W2011611726C86803240 @default.
• W2011611726 hasConceptScore W2011611726C93304396 @default.
• W2011611726 hasConceptScore W2011611726C95444343 @default.
• W2011611726 hasIssue "4" @default.
• W2011611726 hasLocation W20116117261 @default.
• W2011611726 hasLocation W20116117262 @default.
• W2011611726 hasLocation W20116117263 @default.
• W2011611726 hasLocation W20116117264 @default.
• W2011611726 hasLocation W20116117265 @default.
• W2011611726 hasOpenAccess W2011611726 @default.
• W2011611726 hasPrimaryLocation W20116117261 @default.
• W2011611726 hasRelatedWork W1981002092 @default.
• W2011611726 hasRelatedWork W1995931074 @default.
• W2011611726 hasRelatedWork W1998406437 @default.
• W2011611726 hasRelatedWork W2001853356 @default.
• W2011611726 hasRelatedWork W2003979653 @default.
• W2011611726 hasRelatedWork W2011621188 @default.
• W2011611726 hasRelatedWork W2065076032 @default.
• W2011611726 hasRelatedWork W2123587496 @default.
• W2011611726 hasRelatedWork W2317042293 @default.
• W2011611726 hasRelatedWork W2482160054 @default.

• next