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• W2011625775 abstract "The cell fusing agent described earlier (Stollar and Thomas, 1975) has been studied in greater detail. By electron microscopy it is spherical, measures between 45 and 52 nm in diameter and contains a core structure between 23 and 28 nm in diameter. Viral morphogenesis can be detected by 30 hr after infection, generally in association with membranous structures and cytoplasmic vesicles. Conditions were found (low Ca2+ in the medium, or high cell density) which did not depress yields of CFA from infected cells but did inhibit cell fusion. The CFA contains a 40–42 S ssRNA which is infectious under appropriate conditions. In infected cells, a 40–42 S ssRNA and a 22 S dsRNA are the predominant viral RNA species. The CFA particle contains three structural polypeptides, VP-1 (MW 13,000), VP-2 (MW 16,500), and VP-3 (MW 49,000). VP-2 and VP-3 are glycosylated and are envelope-associated, whereas VP-1 is not glycosylated and is associated with the viral RNA. No antigenic cross reaction could be demonstrated between the CFA, and a variety of flavivirus (group B) antigens. The CFA appears to be an ungrouped togavirus." @default.
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• W2011625775 date "1976-10-01" @default.
• W2011625775 modified "2023-10-17" @default.
• W2011625775 title "Morphological, biochemical, and serological studies on a viral agent (CFA) which replicates in and causes fusion of Aedes albopictus (singh) cells" @default.
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• W2011625775 doi "https://doi.org/10.1016/0042-6822(76)90139-2" @default.
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