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- W2011630286 abstract "RNA editing by adenosine deamination is a process used to diversify the proteome. The expression of ADARs, the editing enzymes, is ubiquitous among true metazoans, and so adenosine deamination is thought to be universal. By changing codons at the level of mRNA, protein function can be altered, perhaps in response to physiological demand. Although the number of editing sites identified in recent years has been rising exponentially, their effects on protein function, in general, are less well understood. This review assesses the state of the field and highlights particular cases where the biophysical alterations and functional effects caused by RNA editing have been studied in detail." @default.
- W2011630286 created "2016-06-24" @default.
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- W2011630286 date "2012-05-01" @default.
- W2011630286 modified "2023-10-14" @default.
- W2011630286 title "A-to-I RNA Editing: Effects on Proteins Key to Neural Excitability" @default.
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- W2011630286 doi "https://doi.org/10.1016/j.neuron.2012.04.010" @default.
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