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• W2011643177 abstract "<h2>Abstract</h2> Adjuvant induced arthritis (AIA) is accompanied by marked changes in the levels of lysosomal enzymes, glycoproteins and metabolic turnover of collagen. The role of a pentacyclic triterpene and eicosapentaenoic acid (EPA) derivative – Lupeol-EPA (50 mg/kg body weight – orally) was tested in vivo in rats. The increased activities of lysosomal enzymes and glycoproteins associated with decreased collagen in arthritic animals were significantly altered to nearly that of controls. Indomethacin (3 mg/kg body weight) was used as a reference compound. The therapeutic usefulness of Lupeol-EPA derivative in inflammatory conditions is attractive and deserves further work in this direction." @default.
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• W2011643177 date "2001-02-01" @default.
• W2011643177 modified "2023-09-26" @default.
• W2011643177 title "A novel derivative pentacyclic triterpene and ω 3 fatty acid [Lupeol-EPA] in relation to lysosomal enzymes glycoproteins and collagen in adjuvant induced arthritis in rats" @default.
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• W2011643177 doi "https://doi.org/10.1054/plef.2001.0245" @default.
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